Results 31 to 40 of about 493,059 (305)

Common and Distinct Functional Brain Networks for Intuitive and Deliberate Decision Making [PDF]

, 2019
Reinforcement learning studies in rodents and primates demonstrate that goal-directed and habitual choice behaviors are mediated through different fronto-striatal systems, but the evidence is less clear in humans.
Balleine, Bodenhausen, Brighton, Bush, Dickinson, Fitts, Hélie, Kastner, Ostlund, Rangel   +9 more
core   +2 more sources

Amphetamine and pseudoephedrine cross-tolerance measured by c-Fos protein expression in brains of chronically treated rats [PDF]

, 2008
Background Pseudoephedrine is a drug commonly prescribed as a nasal decongestant and bronchodilator and is also freely available in cold remedies and medications.
Casalotti, Stefano O., Govitrapong, P., Ruksee, N., Tongjaroenbuangam, W.   +3 more
core   +3 more sources

Region-specific astrogliosis: differential vessel formation contributes to different patterns of astrogliosis in the cortex and striatum

Molecular Brain, 2020
Brain injury causes astrocytes to become reactive (astrogliosis). In this study, we compared astrogliosis in acutely injured cortex and striatum of adult FVB/N mice induced by stereotaxic injection of ATP, a component of danger-associated molecular ...
Haijie Yang, Jiawei An, Insup Choi, Kihwang Lee, Sang-Myun Park, Ilo Jou, Eun-Hye Joe   +6 more
doaj   +1 more source

Novel oligodendroglial alpha synuclein viral vector models of multiple system atrophy: studies in rodents and nonhuman primates

Acta Neuropathologica Communications, 2017
Multiple system atrophy (MSA) is a horrible and unrelenting neurodegenerative disorder with an uncertain etiology and pathophysiology. MSA is a unique proteinopathy in which alpha-synuclein (α-syn) accumulates preferentially in oligodendroglia rather ...
Ronald J. Mandel, David J. Marmion, Deniz Kirik, Yaping Chu, Clifford Heindel, Thomas McCown, Steven J. Gray, Jeffrey H. Kordower   +7 more
doaj   +1 more source

Glutamate delta-1 receptor regulates oligodendrocyte progenitor cell differentiation and myelination in normal and demyelinating conditions.

PLoS ONE, 2023
In this study, we investigated the role of glutamate delta 1 receptor (GluD1) in oligodendrocyte progenitor cell (OPC)-mediated myelination during basal (development) and pathophysiological (cuprizone-induced demyelination) conditions.
Sukanya G Gakare, Jay M Bhatt, Kishore Kumar S Narasimhan, Shashank M Dravid   +3 more
doaj   +1 more source

The Influence of Striatal Astrocyte Dysfunction on Locomotor Activity in Dopamine-depleted Rats

Basic and Clinical Neuroscience, 2021
Introduction: Astrocyte dysfunction is the common pathology failing astrocyte-neuron interaction in neurological diseases, including Parkinson’s Disease (PD).
Dmitry Voronkov, Alla Stavrovskaya, Artyom Olshanskiy, Anastasia Guschina, Rudolf Khudoerkov, Sergey Illarioshkin   +5 more
doaj  

Semi-automatic parcellation of the corpus striatum [PDF]

SPIE Proceedings, 2007
The striatum is the input component of the basal ganglia from the cerebral cortex. It includes the caudate, putamen, and nucleus accumbens. Thus, the striatum is an important component in limbic frontal-subcortical circuitry and is believed to be relevant both for reward-guided behaviors and for the expression of psychosis.
Ramsey, Al-Hakim, Delphine, Nain, James, Levitt, Martha, Shenton, Allen, Tannenbaum   +4 more
openaire   +2 more sources

Pathogenetical significance of porencephalic lesions associated with intracerebral inoculation of sheep with the bovine spongiform encephalopathy (BSE) agent [PDF]

, 2009
Decreased rates of transmission of transmissible spongiform encephalopathies (TSEs) to sheep have been attributed to some polymorphisms of the prion protein (PrP) and to a ‘species barrier’ on interspecies experiments.
Card, Cotran, Detwiler, Foster, Foster, Fraser, Goldmann, González, González, Hamir, Hamir, Hamir, Houston, Houston, Houston, Hunter, Jeffrey, McLennan, Nakaoke, Outram, Weller, Zakharov   +21 more
core   +1 more source

Signaling Overlap between the Golgi Stress Response and Cysteine Metabolism in Huntington’s Disease

Antioxidants, 2021
Huntington’s disease (HD) is caused by expansion of polyglutamine repeats in the protein huntingtin, which affects the corpus striatum of the brain. The polyglutamine repeats in mutant huntingtin cause its aggregation and elicit toxicity by affecting ...
Bindu D. Paul
doaj   +1 more source

Averaging Transformations of Synaptic Potentials on Networks [PDF]

, 2009
The problem of the transformation of microscopic information to the macroscopic level is an intriguing challenge in computational neuroscience, but also of general mathematical importance.
Hamid Reza Noori
core   +3 more sources