Results 111 to 120 of about 720,485 (294)

Almost Periodically Correlated Time Series in Business Fluctuations Analysis

open access: yes, 2012
We propose a non-standard subsampling procedure to make formal statistical inference about the business cycle, one of the most important unobserved feature characterising fluctuations of economic growth.
Lenart, Lukasz, Pipien, Mateusz
core  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Microwave-induced excess quasiparticles in superconducting resonators measured through correlated conductivity fluctuations

open access: yes, 2012
We have measured the number of quasiparticles and their lifetime in aluminium superconducting microwave resonators. The number of excess quasiparticles below 160 mK decreases from 72 to 17 $\mu$m$^{-3}$ with a 6 dB decrease of the microwave power.
Baselmans, J. J. A.   +5 more
core   +2 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Pupil fluctuations track rapid changes in adrenergic and cholinergic activity in cortex

open access: yesNature Communications, 2016
In addition to light intensity, changes in pupil diameter are correlated with mental effort, attention and levels of arousal. Reimer et al. report that across behavioural states, fluctuations in pupil diameter are highly correlated with activity of ...
Jacob Reimer   +6 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The Effects of Glucose Fluctuation on the Severity of Coronary Artery Disease in Type 2 Diabetes Mellitus

open access: yesJournal of Diabetes Research, 2013
Objectives. To explore the difference of glucose fluctuations between the normal subjects and diabetes mellitus (DM) patients and explore their impact on the development of CAD in type 2 DM patients. Methods.
Xingguang Zhang   +5 more
doaj   +1 more source

Bounds and Estimates for the Response to Correlated Fluctuations in Asymmetric Complex Networks

open access: yes, 2021
We study the spreading of correlated fluctuations through networks with asymmetric and weighted coupling. This can be found in many real systems such as renewable power grids. These systems have so far only been studied numerically.
Auer, Sabine   +3 more
core  

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

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