Results 21 to 30 of about 773,776 (201)

Model of the early development of thalamo-cortical connections and area patterning via signaling molecules

, 2004
The mammalian cortex is divided into architectonic and functionally distinct areas. There is growing experimental evidence that their emergence and development is controlled by both epigenetic and genetic factors.
Ermentrout, G. B., Karbowski, Jan
core   +3 more sources

A Model for the Development of the Rhizobial and Arbuscular Mycorrhizal Symbioses in Legumes and Its Use to Understand the Roles of Ethylene in the Establishment of these two Symbioses [PDF]

, 2002
We propose a model depicting the development of nodulation and arbuscular mycorrhizae. Both processes are dissected into many steps, using Pisum sativum L. nodulation mutants as a guideline. For nodulation, we distinguish two main developmental programs,
Albrecht C., Albrecht C., Ardourel M., Azcon-Aguilar C., Balaji B., Balestrini R., Barker D.G., Barker S.J., Barker S.J., Barnes D.K., Bauer P., Besmer Y.L., Blancaflor E.B., Blilou I., Bonfante P., Bonfante P., Boogerd F.C., Borisov A.Y., Borisov A.Y., Borisov A.Y., Brewin N.J., Buée M., Caetano-Anolles G., Cao X.F., Cardenas L., Carroll B.J., Catoira R., Catoira R., Cavagnaro T.R., Chang C., Charon C., Ciardi J., Cohn J., Cook D., Cruz A.F., Davidson A.L., Davidson A.L., de Faria S.M., Dehio C., Drennan D.S.H., Duc G., Duc G., Dugassa G.D., Duodu S., Ehrhardt D.W., Ekdahl I., El Ghachtouli N., Engvild K.C., F C Guinel, Fang Y., Fearn J.C., Felle H.H., Felle H.H., Fernández-López M., Fuchs Y., Fukuda H., Gallaud I., Garriock M.L., Geil R.D., Geil R.D., Geitmann A., Genre A., Genre A., Geurts R., Gianinazzi-Pearson V., Giovannetti M., Giovannetti M., Glick B.R., Gollotte A., Goodlass G., Gremaud M.F., Guinel F.C., Guinel F.C., Guinel F.C., Hall M.A., Hamilton A.J., Harrison M.J., Heidstra R., Hirayama T., Hirsch A.M., Hirsch A.M., Hirsch A.M., Hirsch A.M., Hirsch A.M., Hua J., Hunter W.J., Ishii T., John P., Johnson P.R., Joshi P.A., Kneen B.E., Kneen B.E., Kneen B.E., Kobayashi I., Kolchinsky A., Kombrink E., Le Gal M.F., Lee K.H., Lee K.H., Lee K.H., Lhuissier F.G.P., Ligero F., Ligero F., Lorteau M.-A., Luschnig C., Lynch J., Markwei C.M., Markwei C.M., Marsh J.F., Martínez-Abarca F., Mateos P.F., Mathesius U., Mathesius U., Matsubara Y., Matthysse A.G., Mattoo A.K., McArthur D.A.J., Morandi D., Mort A.J., Morzhina E.V., Mylona P., Nadian H., Nagahashi G., Niebel A., Nukui N., Oldroyd G.E.D., Osborne D.J., Park S.J., Parniske M., Paruvangada V.G., Pawlowski K., Peters N.K., Peterson R.L., Postma J.G., Provorov N.A., R D Geil, Rae A.L., Reddy A.S.N., Resendes C.M., Roberts I.N., Sagan M., Sagan M., Salzer P., Santos R., Santos R., Schauser L., Schmidt J.S., Schneider A., Schultze M., Sen D., Senoo K., Smalle J., Smith F.A., Solano R., Sprent J.I., Sprent J.I., Steen D.A., Stougaard J., Stougaard J., Subba-Rao N.S., Suganuma N., Sugimoto K., Szczyglowski K., Theologis A., Timmers A.C.J., Timmers A.C.J., Todaka I., Tsyganov V.E., Tsyganov V.E., Tsyganov V.E., van Rhijn P., van Spronsen P.C., van Spronsen P.C., van Spronsen P.C., van Workum W.A.T., Vasse J., Vasse J., Vega-Hernandez M.C., Vernoud V., Vierheilig H., Vogel J.P., Voroshilova V.A., Wais R.J., Walker S.A., Wegel E., Wisniewski J.-P., Yang W.-C., Yang W.-C., Yasuta T., Young J.P.W., Yuhashi K.-I., Zaat S.A.J., Zhou L.   +192 more
core   +2 more sources

Whole egg consumption and cortical bone in healthy children [PDF]

, 2018
Eggs contain bioactive compounds thought to benefit pediatric bone. This cross-sectional study shows a positive link between childhood egg intake and radius cortical bone.
Coheley, L.M., Hill Gallant, K.M., Kindler, J.M., Laing, E.M., Lewis, R.D., Oshri, A., Peacock, M., Warden, S.J., Weaver, C.M.   +8 more
core   +1 more source

Does the motor system need intermittent control? [PDF]

, 2014
Explanation of motor control is dominated by continuous neurophysiological pathways (e.g. trans-cortical, spinal) and the continuous control paradigm.
Brembs, Cisek, Cohen, Cornelis van de Kamp, Diedrichsen, Dux, Frank, Gawthrop, Gawthrop, Gawthrop, Gawthrop, Gollee, Haber, Hardwick, Henrik Gollee, Houk, Ian David Loram, Kleinman, Lakie, Levison, Loram, Loram, Loram, Loram, Loram, Loram, Marsden, Martin Lakie, Peter J. Gawthrop, Pruszynski, Redgrave, Redgrave, Ronco, Todorov, Van De Kamp, Van de Kamp, Vince, Yin   +37 more
core   +2 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Exaggerated CpH methylation in the autism-affected brain. [PDF]

, 2017
BackgroundThe etiology of autism, a complex, heritable, neurodevelopmental disorder, remains largely unexplained. Given the unexplained risk and recent evidence supporting a role for epigenetic mechanisms in the development of autism, we explored the ...
Arking, Dan E, Ellis, Shannon E, Gupta, Simone, Moes, Anna, West, Andrew B   +4 more
core   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Linking Visual Cortical Development to Visual Perception [PDF]

, 2000
Defense Advanced Research Projects Agency and the Office of Naval Research (N00014-95-1-0409); National Science Foundation (IRI-97-20333); Office of Naval Research (N00014-95-1 ...
Grossberg, Stephen
core   +1 more source