Results 51 to 60 of about 310,882 (171)

Neonatal valproic acid exposure produces altered gyrification related to increased parvalbumin-immunopositive neuron density with thickened sulcal floors.

PLoS ONE, 2021
Valproic acid (VPA) treatment is associated with autism spectrum disorder in humans, and ferrets can be used as a model to test this; so far, it is not known whether ferrets react to developmental VPA exposure with gyrencephalic abnormalities.
Kazuhiko Sawada, Shiori Kamiya, Ichio Aoki   +2 more
doaj   +1 more source

Lifespan Gyrification Trajectories of Human Brain in Healthy Individuals and Patients with Major Psychiatric Disorders

Scientific Reports, 2017
Cortical gyrification of the brain represents the folding characteristic of the cerebral cortex. How the brain cortical gyrification changes from childhood to old age in healthy human subjects is still unclear.
Bo Cao, Benson Mwangi, Ives Cavalcante Passos, Mon-Ju Wu, Zafer Keser, Giovana B. Zunta-Soares, Dianping Xu, Khader M. Hasan, Jair C. Soares   +8 more
doaj   +1 more source

Altered cortical gyrification patterns in panic disorder: Deficits andpotential compensation

, 2018
Abnormal gyrification patterns may reflect aberrant cortical connectivity during an early period of brain maturation. We here investigated anatomical distribution of cortical gyrification deficits underlying panic disorder and the relationships of these ...
류인균, 임수미, 전찬수
core   +1 more source

Surface-based correlates of cognition along the Alzheimer's continuum in a memory clinic population

Frontiers in Neurology, 2023
Composite cognitive measures in large-scale studies with biomarker data for amyloid and tau have been widely used to characterize Alzheimer's disease (AD).
Michelle M. Coleman, Cierra M. Keith, Cierra M. Keith, Kirk Wilhelmsen, Kirk Wilhelmsen, Rashi I. Mehta, Rashi I. Mehta, Camila Vieira Ligo Teixeira, Mark Miller, Mark Miller, Melanie Ward, Melanie Ward, Ramiro Osvaldo Navia, Ramiro Osvaldo Navia, William T. McCuddy, Pierre-François D'Haese, Pierre-François D'Haese, Marc W. Haut, Marc W. Haut, Marc W. Haut   +19 more
doaj   +1 more source

Genetic Influence on Gyral Peaks

NeuroImage, 2023
Genetic mechanisms have been hypothesized to be a major determinant in the formation of cortical folding. Although there is an increasing number of studies examining the heritability of cortical folding, most of them focus on sulcal pits rather than ...
Ying Huang, Tuo Zhang, Songyao Zhang, Weihan Zhang, Li Yang, Dajiang Zhu, Tianming Liu, Xi Jiang, Junwei Han, Lei Guo   +9 more
doaj   +1 more source

Cortical Plate Gene Expression During Gyrification in Sheep

, 2019
During the process of folding of the cerebral cortex during development –called gyrification due to the presence of gyri (outward folds) and sulci (inward folds)– the cortical plate appears to play a fundamental role.
SEBASTIAN ALONSO QUEZADA (6730538)
core   +1 more source

Cortical gyrification and its relationships with cortical volume, cortical thickness, and cognitive performance in healthy mid-life adults

, 2016
Across species, greater cortical gyrification, or folding of the cortex, has been shown to be associated with higher cognitive abilities and is thought to reflect an evolutionary process aimed at maximizing the number of cerebral computational units ...
Cherbuin, Nicolas, Anstey, Kaarin, Gautam, Prapti, Wen, Wei, Sachdev, Perminder Singh   +4 more
core   +1 more source

Morphometry and gyrification in bipolar disorder and schizophrenia: A comparative MRI study

NeuroImage: Clinical, 2020
Schizophrenia is believed to be a neurodevelopmental disease with high heritability. Differential diagnosis is often challenging, especially in early phases, namely with other psychotic disorders or even mood disorders.
Nuno Madeira, João Valente Duarte, Ricardo Martins, Gabriel Nascimento Costa, António Macedo, Miguel Castelo-Branco   +5 more
doaj   +1 more source

PRNP expression predicts imaging findings in sporadic Creutzfeldt‐Jakob disease

Annals of Clinical and Translational Neurology, 2023
Objective We explored the relationship between regional PRNP expression from healthy brain tissue and patterns of increased and decreased diffusion and regional brain atrophy in patients with sporadic Creutzfeldt‐Jakob disease (sCJD).
Iris J. Broce, Eduardo Caverzasi, Simone Sacco, Ryan Michael Nillo, Matteo Paoletti, Rahul S. Desikan, Michael Geschwind, Leo P. Sugrue   +7 more
doaj   +1 more source

Association between Cortical Gyrification and Major Depression: Clinical Correlates.

Psychopathology
Introduction: Major depressive disorder (MDD) is one of the most frequent psychiatric diseases worldwide. Growing evidence suggests that cortical gyrification measures may present an early risk marker for depression. Medial views of cortical surface reconstructions provide the basis for a simple, expert-rated measure of cortical gyrification.
Buchmann A, Hase A, Ritter CJ, Müller ST, Haynes M, Ghisleni C, O Apos Gorman Tuura R, Kohler CS, Hasler G.   +8 more
europepmc   +4 more sources