Results 71 to 80 of about 310,882 (171)

Early dorsomedial tissue interactions regulate gyrification of distal neocortex

Nature Communications, 2019
The contribution of long-range signaling to cortical gyrification remains poorly understood. In this study, authors demonstrate that the combined genetic loss of transcription factors Lmx1a and Lmx1b, expressed in the telencephalic dorsal midline ...
Victor V. Chizhikov, Igor Y. Iskusnykh, Ekaterina Y. Steshina, Nikolai Fattakhov, Anne G. Lindgren, Ashwin S. Shetty, Achira Roy, Shubha Tole, Kathleen J. Millen   +8 more
doaj   +1 more source

The MacBrain Resource Center (MBRC) rhesus macaque embryonic brain histology datasets

Journal of Anatomy, EarlyView.
We introduce the MacBrain Resource Center (MBRC) Collections of rhesus macaque embryonic brain tissue. Here, we illustrate histo‐ and immunohistology from our dynamically growing Collection 6, which currently contains >10,000 zoomable and downloadable images from n = 14 male and female embryos from early to late in gestation.
Valeria Mendoza‐Silva, Emma Burke, Lucy Greene, Mikhail Rodov, Janja Kopić, Phil Barello, Yury M. Morozov, Keiko Moriya‐Ito, Chiaki Ohtaka‐Maruyama, Zeljka Krsnik, Pasko Rakic, Alvaro Duque   +11 more
wiley   +1 more source

Characterization of postnatal brain injury and behavioural deficits in a rat model of placental insufficiency‐induced fetal growth restriction

The Journal of Physiology, EarlyView.
Abstract figure legend Fetal growth restriction (FGR) is a common pregnancy complication associated with long‐term neurodevelopmental impairments. Using the reduced uterine perfusion pressure (RUPP) rat model of placental insufficiency‐induced FGR, this study demonstrates that FGR leads to persistent anatomical, histological and behavioural ...
Judit Alhama‐Riba, Caroline G. M. de Theije, Valentina Salvi, Dominique Viveen, Sebastiaan W. T. Corstjens, Marijke. E. J. Achterberg, Yohan van de Looij, Freek E. Hoebeek, Cora H. A. Nijboer   +8 more
wiley   +1 more source

Unraveling the Relationship Between Nr4a2 and Fezf1 Expression in the Developing Feline Telencephalon Within the Genoarchitectonic Context of Claustral and Amygdalar Development

Journal of Comparative Neurology, Volume 534, Issue 11, November 2026.
To define the emergence of the claustral complex in relation to the expression patterns of Nr4a2 and Fezf1 in the domestic cat, a species with more protracted prenatal development than the mouse, we performed a genoarchitectonic analysis. Nr4a2 marked differentiating claustral neurons within the LPall mantle, whereas Fezf1 was broadly expressed in the ...
Nikistratos Siskos, Andreas‐Rafail Vasileiou, Evangelia Archontoulaki, Alexandra Tsakalidou‐Rafailidou, Charalampos Ververidis, George Skavdis, Maria E. Grigoriou   +6 more
wiley   +1 more source

Cortical thickness and gyrification index measuring cognition in Parkinson’s disease

International Journal of Neuroscience, 2020
Objective: Cortical dynamics is driven by cortico-cortical connectivity and it characterizes cortical morphological features. These brain surface features complement volumetric changes and may offer improved understanding of disease pathophysiology.
Shefali Chaudhary, S. Senthil Kumaran, Vinay Goyal, G. S. Kaloiya, M. Kalaivani, N. R. Jagannathan, Rajesh Sagar, Nalin Mehta, A. K. Srivastava   +8 more
openaire   +2 more sources

Structural compression and entorhinal vulnerability: Linking tentorial adjacency to tau burden and dementia progression

Alzheimer's &Dementia, Volume 22, Issue 10, October 2026.
Abstract INTRODUCTION Early neurofibrillary tau degeneration in the entorhinal cortex (EC) is a hallmark of Alzheimer's disease (AD) and aging. We propose a biomechanical cascade hypothesis, suggesting proximity to the tentorial incisura (TI) may render the EC susceptible to chronic mechanical stress, potentially contributing to tau pathology.
Luyue Zhang, Ana M. Franceschi, John F. Crary, Frank A. Provenzano, for the Alzheimer's Disease Neuroimaging Initiative   +4 more
wiley   +1 more source

High serum high-density lipoprotein-cholesterol is associated with memory function and gyrification of insular and frontal opercular cortex in an elderly memory-clinic population

NeuroImage: Clinical, 2019
The issue of whether serum lipid marker values are cognitively and neurologically significant for elderly individuals attending a memory clinic has been controversial.
Ryuta Kinno, Yukiko Mori, Satomi Kubota, Shohei Nomoto, Akinori Futamura, Azusa Shiromaru, Takeshi Kuroda, Satoshi Yano, Seiichiro Ishigaki, Hidetomo Murakami, Yasuhiko Baba, Kenjiro Ono   +11 more
doaj   +1 more source

Orbitofrontal and Medial Frontal Gray Matter Volumes Are Associated With Hyperactivity Traits in 2548 Nonclinical Adults

Human Brain Mapping, Volume 47, Issue 14, October 1, 2026.
In 2548 nonclinical adults, smaller orbitofrontal and medial frontal cortex gray matter volumes were associated with higher hyperactivity traits (r = −0.07 to −0.08). These small, robust effects, consistent with ENIGMA ADHD findings, suggest frontal structure–trait mapping extends to the nonclinical ADHD continuum.
Handityo Aulia Putra, Kaechang Park
wiley   +1 more source

The sexually dimorphic impact of maltreatment on cortical thickness, surface area and gyrification [PDF]

, 2016
An extensive literature has detailed how maltreatment experience impacts brain structure in children and adolescents. However, there is a dearth of studies on the influence of maltreatment on surface based indices, and to date no study has investigated ...
Amy L. Palmer, Vanessa B. Puetz, Palmer, AL, McCrory, Eamon J., Philip A. Kelly, Kelly, PA, Puetz, Vanessa, Sophie Samuel, Viding, Essi, Viding, E, Kelly, Philip A., Samuel, S, McCrory, EJ, Essi Viding, Puetz, VB, Eamon J. McCrory, Samuel, Sophie, Palmer, Amy L.   +17 more
core   +2 more sources

Association of altered cortical gyrification and working memory in male early abstinent alcohol-dependent individuals

Brain Research Bulletin
Background: Alcohol dependence (AD) is an addictive disorder with multifaceted neurobiological features. Recent research on the pathophysiological mechanisms of AD has emphasized the important role of dysconnectivity. Cortical gyrification is known to be
Hai-ling Cao, Wei Wei, Ya-jing Meng, Yu-jie Tao, Xia Yang, Tao Li, Wan-jun Guo   +6 more
doaj   +1 more source