Cortical folding alterations in fetuses with isolated non-severe ventriculomegaly [PDF]
NeuroImage: Clinical, 2018 Neuroimaging of brain diseases plays a crucial role in understanding brain abnormalities and early diagnosis. Of great importance is the study of brain abnormalities in utero and the assessment of deviations in case of maldevelopment. In this work, brain
Oualid M. Benkarim +6 more
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Biophysical modeling of anatomically realistic prenatal cortical folding development [PDF]
Nature CommunicationsCortical folds encode the architecture of human cognition, yet the mechanisms that transform the smooth fetal cortex into its convoluted geometry remain elusive.
Jixin Hou +11 more
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Regulatory and coding sequences of TRNP1 co-evolve with brain size and cortical folding in mammals [PDF]
eLife, 2023 Brain size and cortical folding have increased and decreased recurrently during mammalian evolution. Identifying genetic elements whose sequence or functional properties co-evolve with these traits can provide unique information on evolutionary and ...
Zane Kliesmete +11 more
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Motifs of brain cortical folding from birth to adulthood [PDF]
Nature CommunicationsCortical folding of the brain is widely regarded as an interplay between genetic programming and biomechanical forces, closely linked to cytoarchitectonic regionalisation. Abnormal folding patterns are frequently observed in neurodevelopmental conditions
Yourong Guo +10 more
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Exploring the role of the outer subventricular zone during cortical folding through a physics-based model [PDF]
eLife, 2023 The human brain has a highly complex structure both on the microscopic and on the macroscopic scales. Increasing evidence has suggested the role of mechanical forces for cortical folding – a classical hallmark of the human brain.
Mohammad Saeed Zarzor +2 more
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The influence of biophysical parameters in a biomechanical model of cortical folding patterns [PDF]
Scientific Reports, 2021 Abnormal cortical folding patterns, such as lissencephaly, pachygyria and polymicrogyria malformations, may be related to neurodevelopmental disorders.
Xiaoyu Wang +5 more
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Establishing a Baseline for Human Cortical Folding Morphological Variables: A Multisite Study [PDF]
Frontiers in Neuroscience, 2022 Differences in the way human cerebral cortices fold have been correlated to health, disease, development, and aging. However, to obtain a deeper understanding of the mechanisms that generate such differences, it is useful to derive one's morphometric ...
Fernanda H. P. de Moraes +3 more
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A discrete subtype of neural progenitor crucial for cortical folding in the gyrencephalic mammalian brain [PDF]
eLife, 2020 An increase in the diversity of neural progenitor subtypes and folding of the cerebral cortex are characteristic features which appeared during the evolution of the mammalian brain.
Naoyuki Matsumoto +4 more
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Cortical folding pattern of asymptomatic HIV-associated neurocognitive disorders [PDF]
BMC Medical ImagingBackground Subtle alterations in cortical morphology among people living with HIV (PLWH) who exhibit milder or no cognitive impairment remain poorly understood.
Ruili Li +6 more
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Longitudinal Assessment of Abnormal Cortical Folding in Fetuses and Neonates With Isolated Non‐Severe Ventriculomegaly [PDF]
Brain and BehaviorPurpose The impact of ventriculomegaly (VM) on cortical development and brain functionality has been extensively explored in existing literature. VM has been associated with higher risks of attention‐deficit and hyperactivity disorders, as well as ...
Andrea Urru +6 more
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