Results 11 to 20 of about 462,073 (262)
Growth in a Turing Model of Cortical Folding [PDF]
Biomath, 2012 The brain's cerebral cortex is folded into many gyri (hills) and sulci (valleys). Little is known about how the cortex folds or why the folds are located where they are.
Gregory Toole, Monica K. Hurdal
doaj +6 more sources
The genetic architecture of human cortical folding. [PDF]
Sci Adv, 2021 The folding of the human cerebral cortex is a highly genetically regulated process that allows for a much larger surface area to fit into the cranial vault and optimizes functional organization.
van der Meer D +16 more
europepmc +9 more sources
Imaging Local Genetic Influences on Cortical Folding [PDF]
Proceedings of the National Academy of Sciences of the United States of America, 2020 Significance Major gaps remain in our understanding of mechanisms that underlie the folding of the human cerebral cortex. Stereotyped folding in specific cortical locations could be explained by a corresponding anatomical pattern of genetic influences on cortical development, but no direct evidence supports this explanation.
John Blangero +2 more
exaly +5 more sources
Folding drives cortical thickness variations [PDF]
The European Physical Journal Special Topics, 2020 The cortical thickness is a characteristic biomarker for a wide variety of neurological disorders. While the structural organization of the cerebral cortex is tightly regulated and evolutionarily preserved, its thickness varies widely between 1.5 and 4.5
Goriely, Alain +11 more
core +6 more sources
Automatically learning cortical folding patterns [PDF]
2009 IEEE International Symposium on Biomedical Imaging: From Nano to Macro, 2009 A data-driven technique is presented for automatically learn-ing cortical folding patterns from MR brain images of dif-ferent subjects. Cortical patterns are represented in terms of generic scale-invariant image features.
D. Louis Collins +2 more
core +2 more sources
Cortical folding and the potential for prognostic neuroimaging in schizophrenia [PDF]
British Journal of Psychiatry, 2015 In 41 patients with schizophrenia, we used neuroanatomical information derived from structural imaging to identify patients with more severe illness, characterised by high symptom burden, low processing speed, high degree of illness persistence and lower
Iwabuchi, Sarina J. +2 more
core +4 more sources
Reduced Cortical Folding in Mental Retardation [PDF]
American Journal of Neuroradiology, 2010 BACKGROUND AND PURPOSE: MR is a developmental disorder associated with impaired cognitive functioning and deficits in adaptive behavior. With a 2D region of interest-based GI, a preliminary study reported significantly reduced gyrification in the ...
Li, C. +6 more
core +8 more sources
The role of thickness inhomogeneities in hierarchical cortical folding
NeuroImage, 2021 The mammalian brain cortex is highly folded, with several developmental disorders affecting folding. On the extremes, lissencephaly, a lack of folds in humans, and polymicrogyria, an overly folded brain, can lead to severe mental retardation, short life ...
Lucas da Costa Campos +4 more
doaj +6 more sources
International audienceCortical folding has been the focus of intense research over the last 10 years, including animal experimentation, physical modeling and computer simulations. In this chapter we will focus on the folding of the cerebrum.
Toro, Roberto, Heuer, Katja
core +2 more sources
How the cortex gets its folds: an inside-out, connectivity-driven model for the scaling of mammalian cortical folding [PDF]
Frontiers in Neuroanatomy, 2012 Larger mammalian cerebral cortices tend to have increasingly folded surfaces, often considered to result from the lateral expansion of the grey matter (GM), which, in a volume constrained by the cranium, causes mechanical compression that is relieved by ...
Bruno eMota +3 more
doaj +2 more sources