Results 101 to 110 of about 369,799 (284)

A New Case With Cortical Malformation Caused by Biallelic Variants in LAMC3. [PDF]

Neurol Genet, 2022
Abe K, Ando K, Kato M, Saitsu H, Nakashima M, Aoki S, Kimura T.   +6 more
europepmc   +1 more source

Functional Disorder at the Neural Interface: How Disordered Nanostructures Promote Proper Growth and Differentiation in In Vitro Neural Cultures

Advanced Science, EarlyView.
This work provides a practical guide for neuroengineers to design advanced neural interfaces, embracing and tailoring the concept of functional disorder. By bridging 2D and 3D in vitro models, this work highlights how non‐periodic, spatially heterogeneous, multiscale nanotopography can enable more physiologically relevant platforms for studying neural ...
F. Maita, E. Palmieri, I. Lucarini, L. Montaina, L. Maiolo   +4 more
wiley   +1 more source

The relevance of hippocampal malformation with epilepsy and other structural brain abnormalities

, 2018
Objectives:The goal of this study was to investigate the frequency of hippocampal shape, position, and orientation anomalies in epilepsy patients and healthy controls.
Kader KARLI OĞUZ, Karli Oguz, Kader, Gocmen, RAHŞAN, Rahşan Göçmen   +3 more
core   +1 more source

Advances and Perspectives in Graphene‐Based Quantum Dots Enabled Neuromorphic Devices

Advanced Science, EarlyView.
Graphene‐based QDs are zero‐dimensional carbon nanomaterials with pronounced quantum confinement and tunable electronic structures. Herein, we summarize their synthesis strategies and functionalization methods, and highlight their functional roles and operating mechanisms in devices, as well as recent advances in neuromorphic electronics. We anticipate
Yulin Zhen, Wei Zeng, Zherui Zhao, JiYu Zhao, Ziyan Huang, Zhuo Chen, Kui Zhou, Guanglong Ding, Su‐Ting Han, Ye Zhou   +9 more
wiley   +1 more source

Monitoring of cortical somatosensory evoked potentials to determine the safety of sacrificing the anterior cerebral artery

, 1982
Cortical somatosensory evoked potentials (SSEPs) reflect the functional integrity of somatosensory pathways from the site of stimulation to the primary somatosensory cortex.
Grundy, B L, Lina, A, Heros, R C, Nelson, P B   +3 more
core   +1 more source

Remote Magnetomechanical Neuromodulation Uncovers Therapeutic Mechanisms for Alleviating Parkinsonian Symptoms in Freely Moving Mice

Advanced Science, EarlyView.
Magnetomechanical neuromodulation using magnetic nanodiscs enables remote activation of neurons. In a hemiparkinsonian mouse model, alternating magnetic fields actuate the nanodiscs to generate torque that opens mechanosensitive ion channels within the subthalamic nucleus, thereby modulating basal ganglia motor circuitry.
Anouk Wolters, Lorenzo Signorelli, Christian Herff, Sophia Gimple, Renzo Riemens, Gunter Kenis, Kim Rijkers, Hamed Shabani, Jyh‐Jang Sun, Yasin Temel, Hans Clusmann, Danijela Gregurec, Sarah‐Anna Hescham   +12 more
wiley   +1 more source

Human cerebral organoids reveal progenitor pathology in EML1-linked cortical malformation. [PDF]

EMBO Rep, 2022
Jabali A, Hoffrichter A, Uzquiano A, Marsoner F, Wilkens R, Siekmann M, Bohl B, Rossetti AC, Horschitz S, Koch P, Francis F, Ladewig J.   +11 more
europepmc   +1 more source

Changes in vascular density in resected tissue of 97 patients with mild malformation of cortical development, focal cortical dysplasia or TSC-related cortical tubers

, 2019
Recent studies suggested a possible association between malformations of cortical development and microvascular density. In this study we aimed to further elucidate the relation between microvascular density and cortical developmental abnormalities in a ...
Kees P.J. Braun, Pieter van Eijsden, Wim G.M. Spliet, van Rijen, Peter C., Aronica, Eleonora, de Neef, Andrew, Gosselaar, Peter H., Peter H. Gosselaar, Veersema, Tim J., van Eijsden, Pieter, Angelika Mühlebner, Jackelien van Scheppingen, Peter C. van Rijen, Braun, Kees P.J., Tim J. Veersema, Cyrille H. Ferrier, Mühlebner, Angelika, van Scheppingen, Jackelien, Andrew de Neef, Eleonora Aronica, Ferrier, Cyrille H., Spliet, Wim G.M., Brain, Zorglijn FNE Medisch, Pathologie, Pathologie Opleiding, Pathologie Moleculair, Pathologie Pathologen staf, ZL Kinder Ner en Nec Medisch, Cancer   +29 more
core   +1 more source

Organoid Brain‐Machine‐Interface Devices for Central Nervous System Repair

Advanced Science, EarlyView.
We envision organoid brain‐machine‐interface (Organoid‐BMI) devices as new biohybrid bidirectional communication pathways to connect the human CNS and the external world for personalized CNS repair and regeneration. ABSTRACT Central nervous system (CNS) repair and regeneration suffer from tremendous clinical challenges due to current limitations in ...
Yantao Xing, Yang Yang, Zichen Hong, Chunhui Tian, Huiyu Chu, Susanne Clara Prokop, Hongwei Cai, Mingxia Gu, Jason Tchieu, Ken Mackie, Feng Guo   +10 more
wiley   +1 more source

Thyroid hypogenesis is associated with a novel AKT3 germline variant that causes megalencephaly and cortical malformation. [PDF]

Hum Genome Var, 2022
Mori J, Hasegawa T, Miyamoto Y, Kitamura K, Morimoto H, Tozawa T, Pooh RK, Chiyonobu T.   +7 more
europepmc   +1 more source