Results 131 to 140 of about 369,799 (284)

Case Report: Prenatal imaging and genetic integrated diagnosis of SCN2A encephalopathy—a case of cryptical cortical dysplasia caused by a loss-of-function frameshift genetic variant

Frontiers in Neuroscience
ObjectiveSCN2A mutations are linked to postnatal epileptic encephalopathies, but prenatal features are poorly defined. We describe a novel SCN2A frameshift mutations prenatal phenotype and genotype–phenotype correlations.Case reportA fetus with ...
Linyan Zhu, Linyan Zhu, Mei Chen, Huiqing Ding, Minyue Dong, Minyue Dong   +5 more
doaj   +1 more source

A CASE OF BONNEAU SYNDROME ASSOCIATED WITH MULTIPLE RENAL CORTICAL CYSTS

, 2009
A case of Bonneau syndrome associated with multiple renal cortical cysts: We describe a 2-month-old girl with congenital anomalies including facial anomalies.
SEPETCİGİL, OĞUZHAN, OLGUN, Haşim, TATAR, Abdulgani, ORBAK, Zerrin   +3 more
core  

A Multi‐Scale Computational Framework for Evaluating Wireless Neuromodulation Feasibility via Magnetoelectric Nanoparticles

Advanced Science, EarlyView.
A multiscale computational framework links single‐nanoparticle magnetoelectric behavior to tissue‐level electric field distributions, integrating experimental data from nanoparticle characterization and in vitro stimulation setups. Applied to a cortical slice configuration, the framework predicts optimal MENP concentrations and stimulation parameters ...
Marta Bonato, Elric Zhang, Emma Chiaramello, Serena Fiocchi, Giulia Suarato, Valentin Gantenbein, Nathalia Cancino‐Fuentes, Alejandro Suarez‐Perez, Maria V. Sanchez‐Vives, Salvador Pané, Marta Parazzini   +10 more
wiley   +1 more source

TNAP and PHOSPHO1 Function Synergistically to Afford Critical Control Over the Mineralization of the Postnatal Murine Skeleton

Advanced Science, EarlyView.
Biomineralization underpins skeletal development, yet its molecular control remains incompletely understood. Using a novel murine knockout model, this study reveals the essential and complementary roles of PHOSPHO1 and TNAP in postnatal skeletal development.
Lucie E. Bourne, Aikta Sharma, Scott Dillon, Jacob Keen, Soher N. Jayash, Natalie Crump, Lucinda A.E. Evans, Maya Karmali, Worachet Promruk, Claire E. Clarkin, Sonoko Narisawa, Louise Stephen, Brian L. Foster, José Luis Millán, Colin Farquharson, Katherine A. Staines   +15 more
wiley   +1 more source

Self‐Sustaining Sensing Systems: Integration Strategies and Signal–Power Matching in Energy‐Harvesting Electronics

Advanced Science, EarlyView.
Energy‐harvesting‐integrated sensors couple ambient energy conversion with sensing, processing, and wireless communication. This review organizes recent progress through integration architectures and operating principles, revisiting co‐packaged, monolithic, and co‐functional designs together with always‐on, event‐driven, and multi‐modal sensing modes ...
Taehyun Park, Ki‐Yoon Park, Yeonho Choi, Dong‐Myeong Shin, Hong‐Joon Yoon, Hocheon Yoo   +5 more
wiley   +1 more source

Architecture and cellular composition of focal cortical dysplasia type II: qualitative review of histological studies

Frontiers in Cellular Neuroscience
Focal cortical dysplasia (FCD) is a malformation of cortical development strongly associated with drug-resistant epilepsy, particularly in children but also observed in adults. FCD type II is specifically characterised by cortical disorganisation and the
Reyes Castaño-Martín, Alice Metais, Alice Metais, Sorana Ciura, Thomas Blauwblomme, Thomas Blauwblomme, Thomas Blauwblomme   +6 more
doaj   +1 more source

Plant Metabolites Screening Identifies 7‐epi‐10‐Deacetyltaxol Inhibiting Cell Division by Interfering With the Cell Cycle and Microtubule Organization

Advanced Science, EarlyView.
In this study, an efficient screening system is developed for plant metabolites to find a compound, 7‐epi‐10‐deacetyltaxol, inhibits tissue elongation. It suppresses plant growth through brassinosteroid and microtubule pathways. It is later applied to animal cells and human tumor organoids, resulting in similar cell division suppression. These findings
Yan‐Jie Zhang, Yu‐Xuan Bai, Geng G. Tian, Bin Zhang, Ding‐Yi Lu, Qing‐Ping Yao, Wen‐Hao Tian, Xiao‐Na Wei, Jing‐Ting Yang, Ze‐Yu Xiong, Yi Lu, Yu‐Tong Jiang, Chun‐Hui Cai, Yu‐Ming Lu, Xian‐Qing Jia, Li‐Li Jing, Bao‐Jun Yang, Ying‐Xin Qi, Xin‐Xin Han, Ji Wu, Wen‐Hui Lin   +20 more
wiley   +1 more source

A Complex Cortical Malformation Caused by a Mutation in the Tubulin-Encoding TUBB3 Gene. [PDF]

Taehan Yongsang Uihakhoe Chi, 2020
Lee YH, Park NH.
europepmc   +1 more source

STING/Type I Interferon Pathway Activation Confers Multimodal Therapeutic Benefits in Osteomyelitis

Advanced Science, EarlyView.
STING/type I interferon signaling counteracts osteomyelitis through coordinated control of pain, bone destruction, and abscess formation. It inhibits pathogen‐induced nociceptor activation, restrains osteoclast‐mediated bone resorption, and suppresses IL‐1β‐driven neutrophil recruitment.
Yang Chen, Jianhua Lv, Yuanqing Cai, Xuhui Yuan, Hongxin Hu, Jiayu Li, Yiming Lin, Hongyan Li, Lan Lin, Huangfeng Lin, Chaofan Zhang, Qijin Wang, Ying Huang, Zida Huang, Wenbo Li, Susheng Niu, Jianhua Lin, Bin Yang, Xinyu Fang, Wenming Zhang   +19 more
wiley   +1 more source

Delayed Functional Networks Development and Altered Fast Oscillation Dynamics in a Rat Model of Cortical Malformation. [PDF]

Front Neurosci, 2020
Kim MJ, Yum MS, Jo Y, Lee M, Kim EJ, Shim WH, Ko TS.   +6 more
europepmc   +1 more source