Results 31 to 40 of about 575,401 (181)
Calcitonin gene-related peptide causes migraine aura
The Journal of Headache and Pain, 2023 Background Although the involvement of calcitonin gene-related peptide (CGRP) in migraines is well-established, its specific role in investigating the aura phase, which often precedes the headache, remains largely unexplored. This study aims to instigate
Haidar M. Al-Khazali +8 more
doaj +1 more source
Advances on the correlation between epilepsy and cortical spreading depression
Chinese Journal of Contemporary Neurology and Neurosurgery, 2023 Cortical spreading depression (CSD) is a pathological depolarization wave caused by the collective depolarization of neurons that propagates slowly along the cerebral cortex and can transiently inhibit brain electrical activity, which is related to a ...
ZHANG Xu, WANG Xiang⁃qing
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Nitric oxide formation during cortical spreading depression is critical for rapid subsequent recovery of ionic homeostasis [PDF]
, 2003 NoCortical spreading depression (CSD) is a temporary disruption of local ionic homeostasis that propagates slowly across the cerebral cortex. Cortical spreading depression promotes lesion progression in experimental stroke, and may contribute to the ...
Urenjak, Jutta A. +5 more
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Molecular Brain, 2023 Familial hemiplegic migraine type-1 (FHM-1) is a form of migraine with aura caused by mutations in the P/Q-type (Cav2.1) voltage-gated calcium channel. Pregabalin, used clinically in the treatment of chronic pain and epilepsy, inhibits P/Q-type calcium ...
Stuart M. Cain +10 more
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An astro-neural-field model with application to cortical spreading depolarization
We present a novel astro-neural-field population model with application to migraine-related cortical spreading depolarization. The model is composed of four spatio-temporal state variables: excitatory and inhibitory membrane potentials, astrocytic ...
Mantegazza, M +5 more
core +5 more sources
Migraine and neuroinflammation: the inflammasome perspective
The Journal of Headache and Pain, 2021 Background Neuroinflammation has an important role in the pathophysiology of migraine, which is a complex neuro-glio-vascular disorder. The main aim of this review is to highlight findings of cortical spreading depolarization (CSD)-induced ...
Oguzhan Kursun +3 more
doaj +1 more source
Neuromodulation: Technology at the Neural Interface, EarlyView., 2021 Abstract Objectives Acute cerebral ischemia is characterized by several pathological processes evolving during time, which contribute to the final tissue damage. Secondary processes, such as prolonged inflammatory response, impaired mitochondrial function and oxidative stress, are responsible for the progression of brain injury to the peri‐infarct area,
Fioravante Capone +8 more
wiley +1 more source
Precapillary sphincters maintain perfusion in the cerebral cortex
Nature Communications, 2020 Precapillary sphincters are mural cells encircling an indentation of blood vessels where capillaries branch off from penetrating arterioles (PAs), but their existence and role in the brain is not fully understood.
Søren Grubb +8 more
doaj +1 more source
, 2021 Galanin modulates in hippocampal neurons the release of neurotransmitters, and thereby it influences neuronal excitability. To test its actions on neurons in cerebral cortex, we recorded ongoing brain activity and induced cortical spreading ...
Gimeno-Ferrer, F, +5 more
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Frontiers in Human Neuroscience, 2020 Transient global amnesia (TGA) is a benign memory disorder with etiologies that have been debated for a long time. The prevalence of stressful events before a TGA attack makes it hard to overlook these precipitating factors, given that stress has the ...
Xuejiao Ding, Xuejiao Ding, Dantao Peng
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