Results 101 to 110 of about 522,558 (297)

Topical corticosteroids in dermatology

Indian Journal of Dermatology, Venereology and Leprology, 2016
Since their introduction, topical corticosteroids have become indispensable in the treatment of various dermatoses. Hydrocortisone was the first compound. Modifications in the basic structure generated in vivo activity and thus different topically active
A. Mehta, N. Nadkarni, Sharmila P Patil, K. Godse, M. Gautam, Shweta Agarwal   +5 more
semanticscholar   +1 more source

NNMT Orchestrates Metabolic‐Epigenetic Reprogramming to Drive Macrophage‐Myofibroblast Transition in Hypertrophic Scarring

Advanced Science, EarlyView.
In macrophage‐myofibroblast transition, upregulated NNMT depletes S‐Adenosylmethionine‌ (SAM) and nicotinamide adenine dinucleotide(NAD+), thereby triggering epigenetic reprogramming via Histone H3 Lysine 27 acetylation (H3K27ac) accumulation at the promoter region of master transcription factor Prrx1.
Xiwen Dong, Weinan Guo, Yuxuan Qian, Wenyan Jin, Xiaozhen Li, Jingyuan Yang, Qingrong Ni, Shuang Wu, Fanni Li, Hua Wang, Chunying Li, Hong Cai   +11 more
wiley   +1 more source

Anti-CD20 Treatment of Autoimmune Hemolytic Anemia Refractory to Corticosteroids and Azathioprine: A Pediatric Case Report and Mini Review [PDF]

, 2018
Alexandros Makis, Zoi Kanta, Dimitrios Kalogeropoulos, Nikoloaos Chaliasos   +3 more
openalex   +1 more source

On the use of corticosteroids for 2019-nCoV pneumonia

The Lancet, 2020
L. Shang, Jianping Zhao, Y. Hu, R. Du, B. Cao   +4 more
semanticscholar   +1 more source

Tackling Allergic Airway Inflammation with Organic Sheet‐Like Nanoplatforms by Targeted Elimination of Epithelial Small Extracellular Vesicles

Advanced Science, EarlyView.
In this work, “inorganic‐free” nanosheets, named PNSE are developed using template‐based synthesis technology. The functionalized organic nanosheets exhibit low cytotoxicity, mild protein adsorption, and potent binding efficacy to epithelial sEVs.
Zhaoxu Tu, Junyan Lin, Zhixin Li, Yuefei Zhu, Changyi Xu, Zihan Qiu, Qiumin Wang, Yang Ye, Yihui Wen, Jian Li, Kam W. Leong, Weiping Wen   +11 more
wiley   +1 more source

The road ahead: emerging therapies for primary IgA nephropathy

Frontiers in Nephrology
Primary IgA nephropathy (IgAN) is the most common form of primary glomerulopathy. A slowly progressive disease presenting in the young to middle-aged, most patients with reduced eGFR or proteinuria will progress to end-stage kidney disease (ESKD) in ...
Edward J. Filippone, Rakesh Gulati, John L. Farber   +2 more
doaj   +1 more source

Adrenocortical corticosteroids and megaloblastic anemia responsible ischemic stroke: A case report

, 2023
Hassan Aden Neima, H Boualam, S RAFI, G El MGHARI, N El ANSARI   +4 more
openalex   +2 more sources

Corticosteroid Use and Periodontal Disease: A Systematic Review [PDF]

, 2020
Rebeca Brasil-Oliveira, Álvaro A. Cruz, Viviane Almeida Sarmento, Adelmir Souza‐Machado, Liliane Lins-Kusterer   +4 more
openalex   +1 more source

Decoding Dental Stem Cell Aging: Mechanisms, Therapeutic Strategies, and Beyond

Advanced Science, EarlyView.
Dental stem cell (DSC) aging involves genomic instability, mitochondrial dysfunction, telomere attrition, and epigenetic alterations, leading to impaired proliferation, reduced differentiation potential, and pro‐inflammatory secretory activity. These processes drive cellular senescence and compromise regenerative and immunomodulatory functions, thereby
Xinyuan Zhao, Yunfan Lin, Pei Lin, Ye Lu, Jiarong Zheng, Xu Chen, Zihao Zhou, Li Cui   +7 more
wiley   +1 more source

Prescribing practices of corticosteroids in outpatient dermatology department of Injibara General Hospital, north-West Ethiopia, 2024

Frontiers in Medicine
BackgroundCorticosteroids are among the most frequently prescribed drugs in the world because they are extremely effective for the relief of symptoms of many inflammatory and immune disorders and other conditions.
Alemu Bezabih Tegegnie, Tamiru Alene, Workineh Tamir, Meaza Molla Sineshaw   +3 more
doaj   +1 more source