Synthetic biology tools for engineering Corynebacterium glutamicum
Computational and Structural Biotechnology Journal, 2023 Corynebacterium glutamicum is a promising organism for the industrial production of amino acids, fuels, and various value-added chemicals. From the whole genome sequence release, C. glutamicum has been valuable in the field of industrial microbiology and
Gi Yeon Kim +5 more
doaj +3 more sources
Carotenoid biosynthesis and overproduction in Corynebacterium glutamicum [PDF]
BMC Microbiology, 2012 Heider S, Peters-Wendisch P, Wendisch VF. Carotenoid biosynthesis and overproduction in Corynebacterium glutamicum. BMC Microbiology. 2012;12(1): 198.Background Corynebacterium glutamicum contains the glycosylated C50 carotenoid decaprenoxanthin as ...
Heider, Sabine +2 more
core +6 more sources
Production of the Antimicrobial Roseoflavin With Genetically Engineered Corynebacterium glutamicum [PDF]
Microbial BiotechnologyThe global rise of drug‐resistant bacterial infections underscores an urgent demand for novel antimicrobial agents. Roseoflavin, a naturally occurring riboflavin analog, has emerged as a promising candidate for drug development.
Luciana Fernandes Brito +4 more
doaj +2 more sources
Engineering Dual-Input Glucose- and Temperature-Sensitive Lysis Circuits in Corynebacterium glutamicum for Efficient Intracellular Product Recovery [PDF]
MicroorganismsCorynebacterium glutamicum is a versatile microbial cell factory, but efficient recovery of intracellular macromolecules remains a major challenge. In this study, we engineered environmentally controllable lysis systems to enable programmable product ...
Ziyu Ye +5 more
doaj +2 more sources
Systems metabolic engineering of Corynebacterium glutamicum for efficient l-tryptophan production [PDF]
Synthetic and Systems BiotechnologyCorynebacterium glutamicum is a versatile industrial microorganism for producing various amino acids. However, there have been no reports of well-defined C. glutamicum strains capable of hyperproducing l-tryptophan.
Yufei Dong, Zhen Chen
doaj +2 more sources
Optimizing recombineering in Corynebacterium glutamicum [PDF]
Biotechnology and Bioengineering, 2021 AbstractOwing to the increasing demand for amino acids and valuable commodities that can be produced by Corynebacterium glutamicum, there is a pressing need for new rapid genome engineering tools that improve the speed and efficiency of genomic insertions, deletions, and mutations.
Cheng Li +3 more
openaire +4 more sources
Nature Communications, 2022 Corynebacterium glutamicum is a major workhorse in industrial biomanufacturing of amino acids. Here, the authors employ CRISPR-assisted rational flux-tuning and CRISPRi screening of a L-proline exporter to covert a wild-type C.
Jiao Liu +15 more
doaj +1 more source
Iron Delivery through Membrane Vesicles in Corynebacterium glutamicum
Microbiology Spectrum, 2023 Bacterial cells form and release membrane vesicles (MVs) originating from cellular membranes. In recent years, many biological functions of bacterial MVs have been identified.
Kayuki Kawashima +3 more
doaj +1 more source
Chromosome segregation impacts on cell growth and division site selection in Corynebacterium glutamicum. [PDF]
, 2013 Spatial and temporal regulation of bacterial cell division is imperative for the production of viable offspring. In many rod-shaped bacteria, regulatory systems such as the Min system and nucleoid occlusion ensure the high fidelity of midcell divisome ...
Bramkamp, Marc +3 more
core +8 more sources
Evolutionary engineering of Corynebacterium glutamicum [PDF]
Biotechnology Journal, 2019 A unique feature of biotechnology is that we can harness the power of evolution to improve process performance. Rational engineering of microbial strains has led to the establishment of a variety of successful bioprocesses, but it is hampered by the overwhelming complexity of biological systems.
Stella, Roberto G. +3 more
openaire +3 more sources