The Actinobacterium Corynebacterium glutamicum, an Industrial Workhorse
Journal of Microbiology and Biotechnology, 2016 Starting as a glutamate producer, Corynebacterium glutamicum has played a variety of roles in the industrial production of amino acids, one of the most important areas of white biotechnology. From shortly after its genome information became available, C.
Pil Kim +4 more
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Cloning vector system for Corynebacterium glutamicum [PDF]
Journal of Bacteriology, 1985 A protoplast transformation system has been developed for Corynebacterium glutamicum by using a C. glutamicum-Bacillus subtilis chimeric vector. The chimera was constructed by joining a 3.0-kilobase cryptic C. glutamicum plasmid and the B. subtilis plasmid pBD10. The neomycin resistance gene on the chimera, pHY416, was expressed in C.
Anthony J. Sinskey +7 more
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Ciprofloxacin triggered glutamate production by Corynebacterium glutamicum [PDF]
BMC Microbiology, 2016 Corynebacterium glutamicum is a well-studied bacterium which naturally overproduces glutamate when induced by an elicitor. Glutamate production is accompanied by decreased 2-oxoglutatate dehydrogenase activity. Elicitors of glutamate production by C.
Eberhardt, Dorit, Wendisch, Volker F.
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An improved multi-parametric programming algorithm for flux balance analysis of metabolic networks [PDF]
arXiv, 2018 Flux balance analysis has proven an effective tool for analyzing metabolic networks. In flux balance analysis, reaction rates and optimal pathways are ascertained by solving a linear program, in which the growth rate is maximized subject to mass-balance constraints.
arxiv
Network analysis reveals a potentially 'evil' alliance of opportunistic pathogens inhibited by a cooperative network in human milk bacterial communities [PDF]
arXiv, 2014 The critical importance of human milk to infants and even human civilization has been well established. Although the human milk microbiome has received increasing attention with the expansion of research on the human microbiome, our understanding of the milk microbiome has been limited to cataloguing OTUs and computation of community diversity indexes.
arxiv
Corynebacterium glutamicum possesses β-N-acetylglucosaminidase
BMC Microbiology, 2016 In Gram-positive Corynebacterium glutamicum and other members of the suborder Corynebacterianeae, which includes mycobacteria, cell elongation and peptidoglycan biosynthesis is mainly due to polar growth. C. glutamicum lacks an uptake system for the peptidoglycan constituent N-acetylglucosamine (GlcNAc), but is able to catabolize GlcNAc-6-phosphate ...
Matano, Christian +5 more
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Robust Approximate Characterization of Single-Cell Heterogeneity in Microbial Growth [PDF]
arXivLive-cell microscopy allows to go beyond measuring average features of cellular populations to observe, quantify and explain biological heterogeneity. Deep Learning-based instance segmentation and cell tracking form the gold standard analysis tools to process the microscopy data collected, but tracking in particular suffers severely from low temporal ...
arxiv
Biosynthesis of L-lysine from paper hydrolysate with Corynebacterium glutamicum and Brevibacterium sp.. [PDF]
, 1983 J. Pelechová +2 more
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Electrotransformation of Brevibacterium lactofermentum and Corynebacterium glutamicum: growth in tween 80 increases transformation frequencies [PDF]
, 1989 J Haynes
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Deep-Ace: LSTM-based Prokaryotic Lysine Acetylation Site Predictor [PDF]
arXivAcetylation of lysine residues (K-Ace) is a post-translation modification occurring in both prokaryotes and eukaryotes. It plays a crucial role in disease pathology and cell biology hence it is important to identify these K-Ace sites. In the past, many machine learning-based models using hand-crafted features and encodings have been used to find and ...
arxiv