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Reduction of protein volume and compressibility by macromolecular cosolvents: dependence on the cosolvent molecular weight

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 1998
The partial specific volume (V) and adiabatic compressibility (beta) of myoglobin have been shown to be reduced by small cosolvents such as glycerol (A. Priev, A. Almagor, S. Yedgar, B. Gavish, Biochemistry 35 (1996) 2061-2066). To elucidate the effect of the cosolvent size on these protein properties, in the present study we determined V and beta of ...
A, Almagor   +4 more
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Enhanced Contact of Cosolvent and DNAPL in Porous Media by Concurrent Injection of Cosolvent and Air

Environmental Science & Technology, 2002
Dense nonaqueous phase liquid (DNAPL) contamination is a major environmental problem. Cosolvent flooding is proposed as a remedial alternative to water flooding. The efficacy of cosolvent flooding is a function of the degree of contact between the injected remedial fluid and the resident DNAPL Poor contact may result from remedial fluids traveling in ...
Seung-Woo, Jeong   +2 more
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Solubility of hydrophobic compounds in water–cosolvent mixtures: Relation of solubility with water–cosolvent interactions

Journal of Pharmaceutical Sciences, 2010
The solubility of organic compounds in mixtures of water and an organic cosolvent can be reasonably estimated from the solubility values in the neat solvents and the composition of the solvent mixture, by means of the log-linear solubilization model. However, deviations from the model are frequently observed in different degree.
Yasuhiro, Miyako   +5 more
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Cosolvent effects on the growth of amyloid fibrils

Current Opinion in Structural Biology, 2020
Cells are equipped with cosolvents that modulate protein folding and aggregation to withstand water stress. The effect of cosolvents on the aggregation rates depends on whether the polypeptide sequence is an intrinsically disordered protein (IDP) or can fold into a specific native structure.
Govardhan, Reddy   +2 more
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Polymer cosolvent system

Polymer Bulletin, 1984
Etude de polymethacrylate de phenyle polymethacrylate de (tetramethyl-1,1,3,3 butyl) phenyle et de poly-t-butyl-4 styrene dans le melange THF ...
GARGALLO, L, RIOS, H, RADIC, D
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Surfactant And Cosolvent Flushing

2014
When properly implemented, surfactant and cosolvent flushing technologies can recover substantial quantities of contaminant mass from chlorinated solvent source zones in relatively short time periods. As with most in situ remediation technologies, surfactant and cosolvent flushing are most effective in relatively homogeneous subsurface systems with ...
Kurt D. Pennell   +2 more
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Solubility in Amide–Water Cosolvent Systems II: Cosolvent Excess at Solute Surface

Journal of Pharmaceutical Sciences, 1979
The solubility of methylparaben was determined at 25 degrees in a series of amide-water cosolvent systems. The data were used to demonstrate the possibility of an amide excess at or near the ester solute over that in the bulk solvent. The analysis, stemming from an interfacial tension-solute area solubility model proposed by earlier workers, involved ...
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Cosolvency of Dimethyl Isosorbide for Steroid Solubility

Pharmaceutical Research, 1991
Dimethyl isosorbide (DMI), which is currently under investigation for its potential use as a pharmaceutical vehicle and drug permeation enhancer, is a water-miscible liquid with relatively low viscosity. The solubilization behavior of DMI as a cosolvent for nonpolar drugs was characterized via dielectric constant measurements of binary solvent systems ...
H, Zia   +3 more
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Simplifying the Electrolyte Systems with the Functional Cosolvent

ACS Applied Materials & Interfaces, 2019
The state-of-the-art electrolytes utilized in lithium-ion batteries are based on liquid carbonates combining a number of additives to fulfill the practical requirements including safety and low temperature. The plenty of components result in the quadruple times of probable radical groups involved into the interfacial reactions, rendering it too ...
Yinping Qin   +7 more
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Effects of Cosolvents on the Hydration of Carbon Nanotubes

Journal of the American Chemical Society, 2009
Molecular dynamics simulations of a nonpolar single-walled carbon nanotube (SWNT) solvated in aqueous solutions of urea, methanol, and trimethylamine N-oxide (TMAO) show clearly the effects of cosolvents on the hydration of the interior of the SWNT.
Lijiang, Yang, Yi Qin, Gao
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