Results 171 to 180 of about 486 (202)
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Solubilization of Fluasterone in cosolvent/cyclodextrin combinations
International Journal of Pharmaceutics, 2003The combined effect of cosolvent (methanol (MeOH), ethanol (EtOH), or n-propanol (n-PrOH)) and complexant hydroxypropyl-beta-cyclodextrin (HP beta CD) on the solubility of Fluasterone is evaluated and explained with a simple equation. The calculated constants in the equation not only quantitatively describe the dependence of drug solubility on ...
Yan, He, Ping, Li, Samuel H, Yalkowsky
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Solubilization of Biphenyl Dimethyl Dicarboxylate by Cosolvency
Drug Development and Industrial Pharmacy, 1999Biphenyl dimethyl dicarboxylate (BDD) is a synthetic analogue of schizandrin C, one of the components isolated from Fructus schizandrae, and has been widely prescribed for improvement of liver functions and symptoms of patients with liver disease. However, its oral preparations have been known to have limited bioavailability due to its extremely low ...
S K, Han, G Y, Kim, Y H, Park
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Effect of cosolvents on the solubility of hydrocarbons in water
Environmental Science & Technology, 1988Cas de la solubilite du n-hexane en solution aqueuse en presence de cosolvant methanol ou methyl-ter-butyl ether et du benzene, en presence de methyl-ter-butyl ...
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Cosolvent effects on sorption isotherm linearity
Journal of Contaminant Hydrology, 2002Sorption-desorption hysteresis, slow desorption kinetics, and other nonideal phenomena have been attributed to the differing sorptive characteristics of the natural organic polymers associated with soils and sediments. In this study, aqueous and mixed solvent systems were used to investigate the effects of a cosolvent, methanol, on sorption isotherm ...
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Protein volume changes on cosolvent denaturation
Biophysical Chemistry, 2005A thermodynamic relationship is obtained which links the effect of a cosolvent on the denaturation equilibrium of a protein to the effect of the cosolvent on the change in partial molar volume (pmv) of a protein on denaturation. The relationship uses the concept of preferential interactions and is exact for an infinitely dilute protein. Analysis of the
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Cosolvent Effects on Diuron Solubility
Journal of Pharmaceutical Sciences, 1991L A, Hardaway, S H, Yalkowsky
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In-Situ Solubilization by Cosolvent and Surfactant—Cosolvent Mixtures
1999Michael D. Annable +3 more
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LCST/UCST transition of acrylate copolymer with cosolvency behaviors in alcohol aqueous solutions
Journal of Molecular Liquids, 2023Xinyu Ma, Ben Niu, Xianru He
exaly