Results 151 to 160 of about 563 (201)
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Cosolvent control of substrate inhibition in cosolvent stimulation of β-glucuronidase activity
Biochemical and Biophysical Research Communications, 1977Abstract Bacterial β-glucuronidase exhibits a considerable increase in specific activity, upon addition of suitable organic cosolvents to aqueous systems. The effect is especially marked with three to five carbon alcohols; a nine fold increase was observed in this study using t-butanol in the range of 10% by volume of t-butanol in water.
P S, Pesheck, R E, Lovrien
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International Journal of Pharmaceutics, 1999
Previously published cosolvency models are critically evaluated in terms of their ability to mathematically correlate solute solubility in binary solvent mixtures as a function of solvent composition. Computational results show that the accuracy of the models is improved by increasing the number of curve-fit parameters.
B J Clark +2 more
exaly +2 more sources
Previously published cosolvency models are critically evaluated in terms of their ability to mathematically correlate solute solubility in binary solvent mixtures as a function of solvent composition. Computational results show that the accuracy of the models is improved by increasing the number of curve-fit parameters.
B J Clark +2 more
exaly +2 more sources
Cosolvent Assisted Protein Refolding
Nature Biotechnology, 1990The use of cosolvents in aqueous systems has been shown to enhance protein refolding and decrease aggregation. In this study, we have used polyethylene glycol (PEG) in the molecular weight range of 1000 to 8000 Daltons to effectively increase the rate of refolding and prevent aggregation of the model protein, bovine carbonic anhydrase B (CAB).
J L, Cleland, D I, Wang
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Cosolvent Effects on Protein Stability
Annual Review of Physical Chemistry, 2013Proteins are marginally stable, and the folding/unfolding equilibrium of proteins in aqueous solution can easily be altered by the addition of small organic molecules known as cosolvents. Cosolvents that shift the equilibrium toward the unfolded ensemble are termed denaturants, whereas those that favor the folded ensemble are known as protecting ...
Deepak R, Canchi, Angel E, García
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Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 1998
The partial specific volume (V) and adiabatic compressibility (beta) of myoglobin have been shown to be reduced by small cosolvents such as glycerol (A. Priev, A. Almagor, S. Yedgar, B. Gavish, Biochemistry 35 (1996) 2061-2066). To elucidate the effect of the cosolvent size on these protein properties, in the present study we determined V and beta of ...
A, Almagor +4 more
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The partial specific volume (V) and adiabatic compressibility (beta) of myoglobin have been shown to be reduced by small cosolvents such as glycerol (A. Priev, A. Almagor, S. Yedgar, B. Gavish, Biochemistry 35 (1996) 2061-2066). To elucidate the effect of the cosolvent size on these protein properties, in the present study we determined V and beta of ...
A, Almagor +4 more
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Enhanced Contact of Cosolvent and DNAPL in Porous Media by Concurrent Injection of Cosolvent and Air
Environmental Science & Technology, 2002Dense nonaqueous phase liquid (DNAPL) contamination is a major environmental problem. Cosolvent flooding is proposed as a remedial alternative to water flooding. The efficacy of cosolvent flooding is a function of the degree of contact between the injected remedial fluid and the resident DNAPL Poor contact may result from remedial fluids traveling in ...
Seung-Woo, Jeong +2 more
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Journal of Pharmaceutical Sciences, 2010
The solubility of organic compounds in mixtures of water and an organic cosolvent can be reasonably estimated from the solubility values in the neat solvents and the composition of the solvent mixture, by means of the log-linear solubilization model. However, deviations from the model are frequently observed in different degree.
Yasuhiro, Miyako +5 more
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The solubility of organic compounds in mixtures of water and an organic cosolvent can be reasonably estimated from the solubility values in the neat solvents and the composition of the solvent mixture, by means of the log-linear solubilization model. However, deviations from the model are frequently observed in different degree.
Yasuhiro, Miyako +5 more
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Cosolvent effects on the growth of amyloid fibrils
Current Opinion in Structural Biology, 2020Cells are equipped with cosolvents that modulate protein folding and aggregation to withstand water stress. The effect of cosolvents on the aggregation rates depends on whether the polypeptide sequence is an intrinsically disordered protein (IDP) or can fold into a specific native structure.
Govardhan, Reddy +2 more
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Polymer Bulletin, 1984
Etude de polymethacrylate de phenyle polymethacrylate de (tetramethyl-1,1,3,3 butyl) phenyle et de poly-t-butyl-4 styrene dans le melange THF ...
GARGALLO, L, RIOS, H, RADIC, D
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Etude de polymethacrylate de phenyle polymethacrylate de (tetramethyl-1,1,3,3 butyl) phenyle et de poly-t-butyl-4 styrene dans le melange THF ...
GARGALLO, L, RIOS, H, RADIC, D
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Surfactant And Cosolvent Flushing
2014When properly implemented, surfactant and cosolvent flushing technologies can recover substantial quantities of contaminant mass from chlorinated solvent source zones in relatively short time periods. As with most in situ remediation technologies, surfactant and cosolvent flushing are most effective in relatively homogeneous subsurface systems with ...
Kurt D. Pennell +2 more
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