Results 11 to 20 of about 155,291 (181)

Cough Hypersensitivity and Chronic Cough [PDF]

Nature Reviews Disease Primers, 2022
Chronic cough is globally prevalent across all age groups. This disorder is challenging to treat because many pulmonary and extrapulmonary conditions can present with chronic cough, and cough can also be present without any identifiable underlying cause or be refractory to therapies that improve associated conditions.
Stuart Mazzone, Kian Fan Chung, Kefang Lai   +2 more
exaly   +13 more sources

Brainstem processing of cough sensory inputs in chronic cough hypersensitivityResearch in context [PDF]

EBioMedicine
Summary: Background: Chronic cough is a prevalent and difficult to treat condition often accompanied by cough hypersensitivity, characterised by cough triggered from exposure to low level sensory stimuli. The mechanisms underlying cough hypersensitivity
Aung Aung Kywe Moe, Nabita Singh, Matthew Dimmock, Katherine Cox, Lorcan McGarvey, Kian Fan Chung, Alice E. McGovern, Marcus McMahon, Amanda L. Richards, Michael J. Farrell, Stuart B. Mazzone   +10 more
doaj   +8 more sources

Chronic cough. Cough reflex hypersensitivity syndrome

Revista Alergia México, 2019
The cough reflex is a protective mechanism of the airway; it avoids bronchoaspiration and its complications and, when it is altered, it can appear as a hypersensitivity syndrome; cough per se is the most common symptom for which medical consultation is ...
José Antonio Sacre-Hazouri, Lauralicia Sacre   +1 more
doaj   +4 more sources

Cough Hypersensitivity Syndrome: Why Its Use Is Inappropriate in Children [PDF]

Journal of Clinical Medicine, 2023
In children and adults, chronic cough is a common symptom presenting to health professionals worldwide. It is internationally accepted that children with chronic cough should be managed with pediatric specific management guidelines.
Anne B Chang, Ahmad Kantar, Hannah E O'Farrell   +2 more
exaly   +4 more sources

Peripheral and central mechanisms of cough hypersensitivity. [PDF]

J Thorac Dis, 2020
Chronic cough is a difficult to treat symptom of many respiratory and some non-respiratory diseases, indicating that varied pathologies can underpin the development of chronic cough. However, clinically and experimentally it has been useful to collate these different pathological processes into the single unifying concept of cough hypersensitivity ...
Singh N, Driessen AK, McGovern AE, Moe AAK, Farrell MJ, Mazzone SB.   +5 more
europepmc   +8 more sources

Cough Hypersensitivity as a Neuro-Immune Interaction [PDF]

Clinical and Translational Allergy, 2015
AbstractCough is an intrinsic protective reflex. However, chronic cough affects a considerable proportion of general population and has a major impact on quality of life. A recent paradigm shift to ‘cough hypersensitivity syndrome’ suggests that chronic cough arises from hypersensitivity of the airway sensory nerves.
Woo-Jung Song, Yoon-Seok Chang
exaly   +5 more sources

Cough hypersensitivity and suppression in COPD

European Respiratory Journal, 2020
Cough reflex hypersensitivity and impaired cough suppression are features of chronic refractory cough (CRC). Little is known about cough suppression and cough reflex hypersensitivity in cough associated with chronic obstructive pulmonary disease (COPD). This study investigated the ability of patients with COPD to suppress cough during a cough challenge
Peter S.P. Cho, Hannah V. Fletcher, Irem S. Patel, Richard D. Turner, Caroline J. Jolley, Surinder S. Birring   +5 more
openaire   +4 more sources

Chronic cough hypersensitivity syndrome. [PDF]

Cough, 2013
Chronic cough has been suggested to be due to three conditions, asthma, post nasal drip, and reflux disease. A different paradigm has evolved in which cough is viewed as the primary condition characterised by afferent neuronal hypersensitivity and different aspects of this syndrome are manifest in the different phenotypes of cough.
Morice AH.
europepmc   +7 more sources

Unnerving Cough in CANVAS: Cough Hypersensitivity Despite Airway Nerve Depletion. [PDF]

Lung
Abstract Introduction Cerebellar ataxia with neuropathy and vestibular areflexia syndrome (CANVAS) is a genetic neurodegenerative condition associated with chronic cough and cough hypersensitivity. The neuropathic mechanisms underlying cough in CANVAS are unknown.
Hirons B, Rhatigan K, McNulty W, Turner RD, Hull JH, Jolley CJ, Hadden RD, Ribeiro A, Cortese A, Cho PSP, Al-Sarraj S, Serra J, Bannister P, Smith CB, Drake MG, Birring SS.   +15 more
europepmc   +6 more sources

Is laryngeal hypersensitivity the basis of unexplained or refractory chronic cough? [PDF]

ERJ Open Research, 2021
Refractory chronic cough (RCC) and unexplained chronic cough (UCC) are common problems seen in primary care and subspecialty clinics. The role of cough hypersensitivity and laryngeal dysfunction in contributing to the persistence of cough in RCC/UCC is ...
Krishna M. Sundar, Amanda Carole Stark, Nan Hu, Julie Barkmeier-Kraemer   +3 more
doaj   +2 more sources