Postoperative exacerbated cough hypersensitivity syndrome induces dramatic respiratory alkalosis, lactatemia, and electrolyte imbalance [PDF]
BMC AnesthesiologyBackground The perioperative management of patients with chronic cough or cough hypersensitivity syndrome and its sometimes severe effects is currently under-researched and under-reported.
Sascha Jan Baettig +4 more
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Unraveling the neuro-immune axis in cough hypersensitivity: from pathogenesis to synergistic management [PDF]
Frontiers in MedicineCough Hypersensitivity Syndrome (CHS) stands as the definitive pathological phenotype of refractory chronic cough, characterized by a sensory nervous system that over-reacts to even trivial, low-threshold stimuli.
Dingyi Shi +12 more
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Clarifying Terminology in Chronic Cough: The Evolving Role of Cough Hypersensitivity Syndrome [PDF]
The Clinical Respiratory JournalChronic cough is defined as a cough lasting no less than 8 weeks, and 10%–42% of patients with chronic cough retain their cough after comprehensive examination and treatment.
Zihang Wang +8 more
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The Genetic Architecture of Chronic Cough: From Sensory Hypersensitivity to Treatable Trait [PDF]
Pulmonary TherapyChronic cough is a prevalent global clinical disorder with substantial quality-of-life impairment, and refractory cases remain a major unmet medical need.
Ran Dong, Mengru Zhang, Alyn H. Morice
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Physiological mechanisms and therapeutic targets in chronic cough [PDF]
Physiological ReportsCough is a vital defensive reflex that safeguards the airways; however, it can become maladaptive and pathological. Chronic cough (>8 weeks in duration) affects up to 10% of the global adult population and is associated with considerable health status ...
James C. Brown +3 more
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Chronic ‘cough hypersensitivity syndrome’: A more precise label for chronic cough [PDF]
Pulmonary Pharmacology & Therapeutics, 2011 Chronic cough remains a challenge to many clinicians because there is often no diagnostic link to causation, and because indirect antitussives are largely ineffective. Chronic cough can also be a predominant symptom associated with many chronic respiratory diseases such as COPD, asthma and pulmonary fibrosis.
K.F. Chung, Chung, K F
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Treatable traits in chronic cough: a prospective evaluation for predicting cough persistence
ERJ Open ResearchBackground The concept of treatable traits has been proposed for managing chronic cough; however, evidence supporting its clinical utility remains limited.
Yeonhee Kim +22 more
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Parainfluenza 3-Induced Cough Hypersensitivity in the Guinea Pig Airways. [PDF]
PLoS ONE, 2016 The effect of respiratory tract viral infection on evoked cough in guinea pigs was evaluated. Guinea pigs were inoculated intranasally with either parainfluenza type 3 (PIV3) and cough was quantified in conscious animals.
Eric J Zaccone +8 more
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Eosinophilic tracheobronchitis with cough hypersensitivity caused by Streptomyces albus antigen
Allergology International, 2000 A 52-year-old woman is reported with atopic cough, in whom bronchoprovocation with Streptomyces albus antigen induced cough and bronchoscopic biopsy revealed eosinophilic tracheobronchitis.
Haruhiko Ogawa +4 more
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Efficacy of Gefapixant, a P2X3 Antagonist, for Refractory Atopic Cough
International Medical Case Reports Journal, 2023 Yoshihisa Ishiura, Shosaku Nomura, Yuka Ishii, Kai Imai, Yusuke Sawai, Takeshi Tamaki, Toshiki Shimizu, Naoyuki Miyashita, Tomoki Ito First Department of Internal Medicine, Kansai Medical University, Osaka, JapanCorrespondence: Yoshihisa Ishiura, First ...
Ishiura Y +8 more
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