Results 161 to 170 of about 43,230 (246)

Structure‐Guided Engineering of a Promiscuous O‐Methyltransferase for a SAM Regeneration Biocatalysis Platform of Methylated Pharmaceuticals

open access: yesAdvanced Science, Volume 13, Issue 13, 3 March 2026.
A substrate promiscuous and regioselective O‐methyltransferase, SmOMT, is functionally and structurally characterized. A double mutant, SmOMTE152A/I306A, exhibited enhanced catalytic activity. By coupling this mutant with a mutant halide methyltransferase, AtHMTV140T, for SAM regeneration, a superior artificial fusion enzyme, AtHMTV140T‐L95‐SmOMTE152A ...
Xiran Xiong   +11 more
wiley   +1 more source

Parasitic Plant–Host Interactions: Molecular Mechanisms and Agricultural Resistance Strategies

open access: yesAdvanced Science, Volume 13, Issue 16, 18 March 2026.
Parasitic plants devastate global agriculture through sophisticated molecular interactions with host crops. This review synthesizes current understanding of parasitic plant‐host interactions, from strigolactone‐mediated germination and haustorium formation to host defense mechanisms.
Jiayang Shi, Qi Xie, Feifei Yu
wiley   +1 more source

Coumarin Derivatives as Anticancer Agents: Mechanistic Landscape with an Emphasis on Breast Cancer. [PDF]

open access: yesMolecules
Hacholli VB   +7 more
europepmc   +1 more source

ROS‐Responsive Wedelolactone Hydrogel Promotes Intervertebral Disc Repair by Disrupting the NF‐κB–LCN2 Inflammatory Feedback Loop

open access: yesAdvanced Science, Volume 13, Issue 14, 9 March 2026.
A mechanically robust, ROS‐responsive hydrogel is engineered to treat intervertebral disc degeneration by targeting the NF‐κB–LCN2 inflammatory feedback loop. By delivering wedelolactone specifically within oxidative niches, this system disrupts macrophage–disc cell crosstalk.
Zimei Wu   +10 more
wiley   +1 more source

Coumarin-1,2,4-Triazole hybrids as potential agents against Brassicogethes aeneus (Fabricius 1775). [PDF]

open access: yesSci Rep
Šubarić D   +7 more
europepmc   +1 more source

Intramolecular Synergy of CO2 Activation and H Spillover on Heteronuclear Dual‐Metal Phthalocyanine Assemblies for Selective CO2 Photoreduction

open access: yesAdvanced Science, Volume 13, Issue 14, 9 March 2026.
The CuNiPc/BiVO4 heterojunction is designed and synthesized for selective CO2 photoreduction. The cascade interfacial Z‐scheme charge transfer and the intramolecular synergy of Cu–Ni dual sites on CO2 activation and H spillover contribute to the high photocatalytic performance and selectivity. ABSTRACT Solar‐driven CO2 conversion holds great promise in
Ye Liu   +10 more
wiley   +1 more source

Evaluation of the Antimicrobial, Cyto-Genotoxic, and Antigenotoxic Activity of Dipteryx odorata Seed Extracts. [PDF]

open access: yesInt J Mol Sci
Dormousoglou M   +10 more
europepmc   +1 more source

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