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Coumarins in the tumor-immune application: from molecular mechanisms to therapeutic innovations [PDF]
Frontiers in ImmunologyCoumarin compounds represent a class of natural or synthetic molecules characterized by a benzo-α-pyrone skeleton. Their diverse substituents and extensive biological activities have garnered significant attention in the fields of anti-tumor therapy and ...
Yufan Zhao +4 more
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Coumarins in Anticancer Therapy: Mechanisms of Action, Potential Applications and Research Perspectives [PDF]
PharmaceuticsCoumarins are natural organic compounds widely found in plants that show promising anticancer properties. This article reviews the current research on the mechanisms of action of coumarins in cancer therapy, including the induction of apoptosis ...
Tomasz Piotr Kubrak +2 more
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Coumarins as Fungal Metabolites with Potential Medicinal Properties
Antibiotics, 2022 Coumarins are a structurally varied set of 2H-chromen-2-one compounds categorized also as members of the benzopyrone group of secondary metabolites. Coumarin derivatives attract interest owing to their wide practical application and the unique reactivity
Olga M. Tsivileva +2 more
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Coumarins of genus Ferula L. (Apiaceae Lindl.)
Eurasian Chemico-Technological Journal, 2023 The biologically active coumarins from Ferula L. species of the family Apiaceae Lindl. for the period 1970 to 2022 have been reviewed. The phytochemical investigation of different parts of Ferula L., including gum resin, leaves, fruits, seeds, roots ...
T.S. Khosnutdinova +3 more
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Coumarin derivatives as antifungal agents - A review
Czech Journal of Food Sciences, 2023 Coumarins and pyridines are a promising class of naturally occurring bioactive heterocycles with unique physical and chemical properties. Compounds containing the coumarin framework possess a wide range of pharmacological, biological, and physiological ...
Mirjana Lončar +2 more
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Molecules, 2020 In this study, eight coumarins (coumarins 1–8) are proposed as near-UV and blue light sensitive photoinitiators/photosensitizers for the cationic polymerization (CP) of epoxysilicones when combined with 4-isopropyl-4’-methyldiphenyliodonium tetrakis ...
Mira Abdallah +3 more
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Journal of Enzyme Inhibition and Medicinal Chemistry, 2022 Different 2,4-thiazolidinedione-tethered coumarins 5a–b, 10a–n and 11a–d were synthesised and evaluated for their inhibitory action against the cancer-associated hCAs IX and XII, as well as the physiologically dominant hCAs I and II to explore their ...
Wagdy M. Eldehna +12 more
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Detection of coumarin derivatives of Viola odorata cultivated in Iraq
Journal of Pharmacy and Bioallied Sciences, 2023 Like other members of the viola family, Viola odorata may be found naturally occurring in Europe and Asia. This little plant is tough and perennially herbaceous. It's also known as sweet violet and English violet.
Zainab Aziz Ali +2 more
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A Review on Anti-Tumor Mechanisms of Coumarins
Frontiers in Oncology, 2020 Coumarins are a class of compound with benzopyrone as their basic structure. Due to abundant sources, easy synthesis, and various pharmacological activities, coumarins have attracted extensive attention from researchers.
Yi Wu +4 more
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Natural coumarins: Preclinical evidence-based potential candidates to alleviate diabetic nephropathy
Phytomedicine Plus, 2022 Background: Cis-o-hydroxycinnamic acid lactones, referred to as natural coumarin, have a basic skeleton of benzopyranone in their structure. The natural coumarins are typically found abundantly in roots, rhizomes, bark, and leaves of the plant belonging ...
Sitara Ghosh +6 more
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