Results 71 to 80 of about 12,078 (273)
Viruses, 2020 The global emergence of zoonotic viruses, including poxviruses, poses one of the greatest threats to human and animal health. Forty years after the eradication of smallpox, emerging zoonotic orthopoxviruses, such as monkeypox, cowpox, and vaccinia ...
Natalia Ingrid Oliveira Silva +4 more
doaj +1 more source
Creative activities and skills for bright and gifted children to supplement the Scott, Foresman and Company new basic readers for grade two [PDF]
, 1958 Thesis (Ed.M.)--Boston ...
Murphy, Clara J, Steinberg, Priscilla S
core +1 more source
Vaccinia virus immune evasion: mechanisms, virulence and immunogenicity [PDF]
, 2013 Virus infection of mammalian cells is sensed by pattern recognition receptors and leads to an innate immune response that restricts virus replication and induces adaptive immunity.
Benfield, C T O +6 more
core +1 more source
Human Cyclophilins—An Emerging Class of Drug Targets
Medicinal Research Reviews, EarlyView.ABSTRACT Cyclophilins are a family of enzymes with peptidyl‐prolyl isomerase activity found in all cells of all organisms. To date, 17 cyclophilin isoforms have been identified in the human body, participating in diverse biological processes. Consequently, cyclophilins have emerged as promising targets for drug development to address a wide array of ...
Katarina Jurkova +3 more
wiley +1 more source
CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 572-582, March 2025.ABSTRACT The antitumor efficacy of an intratumoral injection of a genetically engineered oncolytic vaccinia virus carrying human IL‐7 and murine IL‐12 genes (hIL‐7/mIL‐12‐VV) was demonstrated in CT26.WT‐bearing mice. In the CT26.WT‐bearing mouse model, the efficacy of the combination of hIL‐7/mIL‐12‐VV plus the anti‐programmed cell death protein (PD)‐1
Akihiro Yamada +13 more
wiley +1 more source
Non-Human Primate Models of Orthopoxvirus Infections
Veterinary Sciences, 2014 Smallpox, one of the most destructive diseases, has been successfully eradicated through a worldwide vaccination campaign. Since immunization programs have been stopped, the number of people with vaccinia virus induced immunity is declining.
Anne Schmitt +2 more
doaj +1 more source
Genome signatures, self-organizing maps and higher order phylogenies: a parametric analysis [PDF]
, 2007 Genome signatures are data vectors derived from the compositional statistics of DNA. The self-organizing map (SOM) is a neural network method for the conceptualisation of relationships within complex data, such as genome signatures.
Gatherer, Derek
core +4 more sources
Small Methods, EarlyView.A new method to identify proteins involved in the uptake and intracellular trafficking of nanoparticles is presented. After nanoparticle uptake, cells are lysed and the organelles with nanoparticles are purified using fluorescence assisted cell sorting. Next, their composition is determined by proteomic analysis.
Hector Garcia Romeu, Anna Salvati
wiley +1 more source
Dairy production practices and associated risks for bovine vaccinia exposure in cattle, Brazil
New Microbes and New Infections, 2017 A cross-sectional serosurvey was performed to identify environmental features or practices of dairy farms associated with risk for exposure to vaccinia-like viruses in dairy cattle in Brazil.
I.A. Borges +10 more
doaj +1 more source
The Paediatric BCG Vaccine Century: From Historical Success to Future Innovations
Acta Paediatrica, EarlyView.ABSTRACT Aim The tuberculosis (TB) vaccine, Bacille‐Calmette‐Guérin (BCG), protects infants against severe forms of primary TB. Yet, it does not protect against pulmonary reactivation TB in adults. Methods A literature review was conducted between 1st January and 28th February 2025 using PubMed, Google Scholar and reports of the World Health ...
Stefan H. E. Kaufmann
wiley +1 more source