Results 21 to 30 of about 26,709,678 (285)

Cox-2 Inhibitors [PDF]

, 2000
Cyclooxygenase-2 (COX-2) inhibitors constitute a new group of non-steroidal anti-inflammatory drugs (NSAIDs) which, at recommended doses, block prostaglandin production by cyclooxygenase-2, but not by cyclooxygenase-1.
Brooks, P. M., Day, R. O.
core   +2 more sources

The Fall of Titans: The Need to Reassess COX-2 Inhibitors

McGill Journal of Medicine, 2020
N ...
Steven Lin
doaj   +1 more source

Chondroprotective Actions of Selective COX-2 Inhibitors In Vivo: A Systematic Review [PDF]

International Journal of Molecular Sciences, 2020
Marjolein M J Caron, Tim Welting, Peter J Emans   +2 more
exaly   +2 more sources

Combined chemotherapy with cyclooxygenase-2 (COX-2) inhibitors in treating human cancers: Recent advancement.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2020
Chemotherapy with a single chemotherapeutic agent or a combined chemotherapeutic regimen is the clinically standardized treatment for almost all human cancers.
Shuangshuang Li, Min Jiang, Lu Wang, Shu-Wen Yu   +3 more
semanticscholar   +1 more source

Selective COX-2 inhibitors and risk of myocardial infarction [PDF]

, 2005
Selective inhibitors of cyclooxygenase- 2 ( COX- 2, ` coxibs') are highly effective anti-inflammatory and analgesic drugs that exert their action by preventing the formation of prostanoids.
Sohn, Hae-Young, Klauss, V., Schiele, T. M., Krotz, F.   +3 more
core   +1 more source

New horizons in the roles and associations of COX-2 and novel natural inhibitors in cardiovascular diseases

Molecular Medicine, 2021
Age-related cardiovascular disease is the leading cause of death in elderly populations. Coxibs, including celecoxib, valdecoxib, etoricoxib, parecoxib, lumiracoxib, and rofecoxib, are selective cyclooxygenase-2 (COX-2) inhibitors used to treat ...
Wujun Chen, Yingjie Zhong, Nuan Feng, Zhu Guo, Shuai Wang, Dongming Xing   +5 more
doaj   +1 more source

Cyclooxygenase 2 (COX-2) inhibitors

, 2022
Ciklooksigenaza-2 (engl. Cyclooxygenase-2, COX-2) je enzim koji se pojavljuje u bolnim i upaljenim tkivima, dok je u zdravim tkivima uglavnom neaktivan.
Magić, Dina
core   +2 more sources

Biology of cyclooxygenase-2: An application in depression therapeutics

Frontiers in Psychiatry, 2022
Depressive Disorder is a common mood disorder or affective disorder that is dominated by depressed mood. It is characterized by a high incidence and recurrence. The onset of depression is related to genetic, biological and psychosocial factors.
Ying He, Yuanshan Han, Xiaolin Liao, Manshu Zou, Yuhong Wang, Yuhong Wang, Yuhong Wang   +6 more
doaj   +1 more source

Cyclic AMP increases COX-2 expression via mitogen-activated kinase in human myometrial cells [PDF]

, 2011
Cyclic AMP (cAMP) is the archetypal smooth muscle relaxant, mediating the effects of many hormones and drugs. However, recently PGI2, acting via cAMP/PKA, was found to increase contraction-associated protein expression in myometrial cells and to promote ...
Mandeep Kandola, Mark R. Johnson, Kandola, Mandeep, Zhiqing Liang, Johnson, Mark R., Chen, Li, Lei, Kaiyu, Sooranna, Suren R, Phillip R. Bennett, Dimitri Grammatopoulos, Grammatopoulos, Dimitris, Bennett, Phillip, Johnson, Mark R, Suren R. Sooranna, Chen, Li I., Li Chen, Kaiyu Lei, Sooranna, Suren R., Grammatopoulos, Dimitri, Liang, Zhiqing, Bennett, Phillip R   +20 more
core   +1 more source

Identification of MFGE8 and KLK5/7 as mediators of breast tumorigenesis and resistance to COX-2 inhibition

Breast Cancer Research, 2021
Background Cyclooxygenase 2 (COX-2) promotes stemness in triple negative breast cancer (TNBC), highlighting COX-2 as a promising therapeutic target in these tumors.
Jun Tian, Vivian Wang, Ni Wang, Baharak Khadang, Julien Boudreault, Khldoun Bakdounes, Suhad Ali, Jean-Jacques Lebrun   +7 more
doaj   +1 more source