Results 31 to 40 of about 1,351 (168)
The thymus gland is a primary lymphoid organ for T-cell development. Various viral infections can result in disturbance of thymic functions. Medullary thymic epithelial cells (mTECs) are important for the negative selection of self-reactive T-cells to ...
Abdulaziz Alhazmi +10 more
doaj +1 more source
We describe a case of meningo-encephalitis caused by Coxsackievirus group B type 2. Diagnosis was suggested by isolation of virus from faeces and high titres of serum antibody in which Coxsackie virus B2 specific IgM antibody was detected.
Bailey, A. S. +4 more
core +1 more source
Coxsackievirus B exits the host cell in shed microvesicles displaying autophagosomal markers. [PDF]
Coxsackievirus B3 (CVB3), a member of the picornavirus family and enterovirus genus, causes viral myocarditis, aseptic meningitis, and pancreatitis in humans.
Scott M Robinson +19 more
doaj +1 more source
Antiviral and immunoregulatory effects of curcumin on coxsackievirus B3-infected hepatitis
Fulminant hepatitis is a life-threatening complication of coxsackievirus B (CVB) 3 infections. The condition may deteriorate to disseminated intravascular coagulopathy with markedly increased liver enzymes, inflammatory cytokines, and chemokines, which ...
Yu-Jheng Lin +6 more
doaj +1 more source
Combined approaches to flexible fitting and assessment in virus capsids undergoing conformational change [PDF]
Fitting of atomic components into electron cryo-microscopy (cryoEM) density maps is routinely used to understand the structure and function of macromolecular machines.
Shakeel, S. +10 more
core +1 more source
Aspects of Enterovirus Infection Molecular Epidemiology in Sakhalin Region (during years 2016–2018)
Relevance. Annual elevation of enterovirus infection (EVI) incidence in the Russian Federation as well as in the Sakhalin region determine a necessity of continuous surveillance involving molecular-genetic methods and phylogenetic analysis ...
E. Yu. Sapega +4 more
doaj +1 more source
Therapeutics for fulminant hepatitis caused by enteroviruses in neonates
Neonatal infection with nonpolio enteroviruses (EVs) causes nonspecific febrile illnesses and even life-threatening multiorgan failure. Hepatitis, which often results in hepatic necrosis followed by disseminated intravascular coagulopathy, is one of the ...
Li-Chiu Wang +6 more
doaj +1 more source
A novel microRNA promotes coxsackievirus B4 infection of pancreatic β cells
The epidemiological association of coxsackievirus B infection with type 1 diabetes suggests that therapeutic strategies that reduce viral load could delay or prevent disease onset.
Salima Lalani +7 more
doaj +1 more source
The role of inducible nitric oxide synthase in the host response to Coxsackievirus myocarditis
The host response to Coxsackievirus infection is complex, including T lymphocytes, B lymphocytes, natural killer cells, and macrophages. Although Coxsackievirus infection induces expression of inducible nitric oxide synthase (NOS2; EC 1.14.13.39) in ...
Moncada, Salvador +17 more
core +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source

