Results 31 to 40 of about 12,288,625 (151)

Coxsackievirus B exits the host cell in shed microvesicles displaying autophagosomal markers. [PDF]

PLoS Pathogens, 2014
Coxsackievirus B3 (CVB3), a member of the picornavirus family and enterovirus genus, causes viral myocarditis, aseptic meningitis, and pancreatitis in humans.
Scott M Robinson, Ginger Tsueng, Jon Sin, Vrushali Mangale, Shahad Rahawi, Laura L McIntyre, Wesley Williams, Nelson Kha, Casey Cruz, Bryan M Hancock, David P Nguyen, M Richard Sayen, Brett J Hilton, Kelly S Doran, Anca M Segall, Roland Wolkowicz, Christopher T Cornell, J Lindsay Whitton, Roberta A Gottlieb, Ralph Feuer   +19 more
doaj   +1 more source

Effect of Coxsackievirus B4 Infection on the Thymus: Elucidating Its Role in the Pathogenesis of Type 1 Diabetes

Microorganisms, 2021
The thymus gland is a primary lymphoid organ for T-cell development. Various viral infections can result in disturbance of thymic functions. Medullary thymic epithelial cells (mTECs) are important for the negative selection of self-reactive T-cells to ...
Abdulaziz Alhazmi, Magloire Pandoua Nekoua, Hélène Michaux, Famara Sane, Aymen Halouani, Ilka Engelmann, Enagnon Kazali Alidjinou, Henri Martens, Hela Jaidane, Vincent Geenen, Didier Hober   +10 more
doaj   +1 more source

Meningo-encephalitis caused by Coxsackievirus group B type 2. Diagnosis confirmed by measuring intrathecal antibody

, 1984
We describe a case of meningo-encephalitis caused by Coxsackievirus group B type 2. Diagnosis was suggested by isolation of virus from faeces and high titres of serum antibody in which Coxsackie virus B2 specific IgM antibody was detected.
Bailey, A. S., Klapper, P. E., Longson, M., Davies-Jones, G. A.B., Barton, B. W.   +4 more
core   +1 more source

Increased gelatinase B/matrix metalloproteinase 9 (MMP-9) activity in a murine model of acute coxsackievirus B4-induced pancreatitis [PDF]

, 2008
Infection of mice with coxsackievirus B4 results within days in a severe acute necrotizing pancreatitis, which resolves completely within weeks. Gelatinase B or matrix metalloproteinase 9 (MMP-9) has previously been shown to be involved in several models
Armando M. De Palma, Philippe E. Van den Steen, Ghislain Opdenakker, De Palma, Armando M., Opdenakker, Ghislain, Neyts, Johan, Van den Steen, Philippe E., Ilse Van Aelst, Johan Neyts, Aelst, Ilse Van, Verbeken, Erik, Erik Verbeken   +11 more
core   +1 more source

Aspects of Enterovirus Infection Molecular Epidemiology in Sakhalin Region (during years 2016–2018)

Эпидемиология и вакцинопрофилактика, 2019
Relevance.  Annual elevation of enterovirus infection (EVI) incidence in the Russian Federation  as well as in the Sakhalin region determine  a necessity  of continuous  surveillance  involving molecular-genetic  methods  and  phylogenetic  analysis ...
E. Yu. Sapega, L. V. Butakova, O. E. Trotsenko, O. A. Funtusova, G. P. Kovtoniuk   +4 more
doaj   +1 more source

Antiviral and immunoregulatory effects of curcumin on coxsackievirus B3-infected hepatitis

Virus Research, 2023
Fulminant hepatitis is a life-threatening complication of coxsackievirus B (CVB) 3 infections. The condition may deteriorate to disseminated intravascular coagulopathy with markedly increased liver enzymes, inflammatory cytokines, and chemokines, which ...
Yu-Jheng Lin, Li-Chiu Wang, Huey-Pin Tsai, Chia-Yu Chi, Chih-Peng Chang, Shun-Hua Chen, Shih-Min Wang   +6 more
doaj   +1 more source

A novel microRNA promotes coxsackievirus B4 infection of pancreatic β cells

Frontiers in Immunology
The epidemiological association of coxsackievirus B infection with type 1 diabetes suggests that therapeutic strategies that reduce viral load could delay or prevent disease onset.
Salima Lalani, Joseph Knudsen, James Kenney, Didier Hober, C. Michael DiPersio, C. Michael DiPersio, Allen Gerber, Allen Gerber   +7 more
doaj   +1 more source

Cryo‐EM Analysis of Adenovirus Vector Reveals Purification Conditions Leading to Loss of Viral Fiber Proteins and Reduced Infectivity

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Vaccines and gene therapies require efficient delivery of genetic material to host cells. Viral vectors leverage viruses' ability to enter host cells to achieve this. Following the SARS‐CoV‐2 vaccine and novel gene therapies that utilize adenovirus vectors, there has been an increase in the demand for large‐scale production of vectors.
Betsy Widdicombe, Joseph D. Barritt, Nichakorn Pipatpadungsin, Braulio Carrillo Sanchez, Dale Stibbs, Lisa Cooper, Sarah L. Rouse, Daniel G. Bracewell   +7 more
wiley   +1 more source

In type 1 diabetes a subset of anti-coxsackievirus B4 antibodies recognize autoantigens and induce apoptosis of pancreatic beta cells.

PLoS ONE, 2013
Type 1 diabetes is characterized by autoimmune destruction of pancreatic beta cells. The role played by autoantibodies directed against beta cells antigens in the pathogenesis of the disease is still unclear. Coxsackievirus B infection has been linked to
Caterina Bason, Renata Lorini, Claudio Lunardi, Marzia Dolcino, Alessandro Giannattasio, Giuseppe d'Annunzio, Antonella Rigo, Nicoletta Pedemonte, Roberto Corrocher, Antonio Puccetti   +9 more
doaj   +1 more source

Old disease, new twist

Journal of Hospital Medicine, EarlyView.
Abstract An 81‐year‐old man with a history of high‐grade urothelial carcinoma of the bladder and ureter on treatment with atezolizumab and tiragolumab presented to the emergency department with 5 months of malaise, generalized weakness, and fatigue and 2 weeks of subjective fevers. One month prior to presentation, he received an empiric 9‐day course of
Hadi Roudsari, Gurpreet Dhaliwal, Anand D. Jagannath, Alan H. Baik, Sam Brondfield   +4 more
wiley   +1 more source