Results 51 to 60 of about 12,093 (219)

An RNA replication-center assay for high content image-based quantifications of human rhinovirus and coxsackievirus infections [PDF]

, 2010
Background: Picornaviruses are common human and animal pathogens, including polio and rhinoviruses of the enterovirus family, and hepatits A or food-and-mouth disease viruses.
Andreas Jurgeit, Stefan Moese, Pascal Roulin, Alexander Dorsch, Mark Lötzerich, Wai-Ming Lee, Urs F Greber   +6 more
core   +2 more sources

Cardiomyopathy Caused by Coxsackievirus Strain A9 in Previously Healthy Child, Northeastern France, 2024

Emerging Infectious Diseases
We characterized a recombinant mosaic coxsackievirus A9 strain responsible for severe inflammatory cardiomyopathy in a previously healthy child in northeastern France in 2024 by using whole-genome sequencing.
Anne-Laure Lebreil, Maxime Bisseux, Audrey Mirand, Marie Glenet, Yohan N’Guyen, Norhan Taha, Pierre Mauran, Cecile Henquell, Laurent Andreoletti   +8 more
doaj   +1 more source

Coxsackie-adenovirus receptor expression is enhanced in pancreas from patients with type 1 diabetes [PDF]

, 2016
Objectives: One of the theories connecting enterovirus (EV) infection of human islets with type 1 diabetes (T1D) is the development of a fertile field in the islets.
Alhazmi, A, Anagandula, M, Anagandula, M, Anquetil-Besnard, F, Atkinson, M, Breuer, J, Burch, T, Campbell-Thompson, M, Chapman, N, Clare-Salzler, M, Dahl-Jørgensen, K, Depledge, D, Domsgen, E, Dotta, F, Dyahal, S, Eizirik, D, Flodström Tullberg, M, Frisk, G, Frisk, G, Fuxe, J, Gerling, I, Gianani, R, Giepmans, B, Hodik, M, Homann, D, Horwitz, M, Hyöty, H, Hyöty, H, Jelmer, W, Kaddis, J, Kakoola, D, Kalicharan, R, Kent, S, Krogvold, L, Kuipers, J, Kusmartseva, I, Laiho, J, Larsson, P, Leete, P, Lenchik, N, Lloyd, R, Mancarella, F, Marjomaki, V, Morgan, N, Morris, M, Nadler, J, Nigi, L, Nyalwidhe, J, Oikarnen, M, OpDeBeeck, A, Patti, A, Petrosino, J, Piemonti, L, Plagnol, V, Pugliese, A, Richardson, S, Rodriguez-Calvo, T, Russell, M, Sabouri, S, Sarimiento, L, Sarkar, S, Sarmiento, L, Sebastiani, G, Smithee, S, Toniolo, A, Tracy, S, Ventriglia, G, von Herrath, M, Wolters, A, Yang, M   +69 more
core   +1 more source

Development of antiviral therapeutics combating coxsackievirus type B3 infection

Инфекция и иммунитет, 2021
Enteroviruses comprise highly diverse group of single-stranded positive RNA viruses belonging to Enterovirus genus, Picornaviridae family. They are the most prevalent viruses worldwide highlighted by high resistance to environmental cues.
A. S. Volobueva, V. V. Zarubaev, K. S. Lantseva   +2 more
doaj   +1 more source

Isoform-specific expression of the Coxsackie and adenovirus receptor (CAR) in neuromuscular junction and cardiac intercalated discs [PDF]

, 2004
Background The Coxsackie and adenovirus receptor (CAR) has a restricted expression pattern in the adult. In skeletal muscle, although CAR is expressed in immature fibers, its transcript levels are barely detectable in mature muscle.
Karpati George, Sollerbrant Kerstin, Allen Carol, Sinnreich Michael, Holland Paul C, Shaw Christian A, Nalbantoglu Josephine   +6 more
core   +2 more sources

Enhanced genomic stability of new miRNA-regulated oncolytic coxsackievirus B3

Molecular Therapy: Oncolytics, 2022
Genetic modification of coxsackievirus B3 (CVB3) by inserting target sequences (TS) of tumor-suppressive and/or organ-selective microRNAs (miRs) into viral genome can efficiently eliminate viral pathogenesis without significant impacts on its oncolytic ...
Huitao Liu, Amirhossein Bahreyni, Yasir Mohamud, Yuan Chao Xue, William W.G. Jia, Honglin Luo   +5 more
doaj   +1 more source

Coxsackie B2 Virus Infection Causing Multiorgan Failure and Cardiogenic Shock in a 42-Year-Old Man [PDF]

, 2019
Infections from coxsackie B2 viruses often cause viral myocarditis and, only rarely, multisystem organ impairment. We present the unusual case of a 42-year-old man in whom coxsackie B2 virus infection caused multiorgan infection, necessitating distal ...
Abdou, Mahmoud H., Hadi, M. Azam, Hopkins, Kali A.   +2 more
core   +1 more source

Seroprevalence of Coxsackievirus B3 in Yantai, China

Japanese Journal of Infectious Diseases, 2013
Coxsackievirus B3 (CVB3) is an important human pathogen, which is frequently associated with aseptic meningitis and encephalitis in many parts of the world. However, the seroprevalence of this viral infection in China is not well understood; therefore, in the present study, we conducted a serological survey in which 373 serum samples obtained from ...
Zexin, Tao, Bo, Li, Aiqiang, Xu, Yao, Liu, Lizhi, Song, Suting, Wang, Ping, Xiong, Xiaojuan, Lin, Yanyan, Song   +8 more
openaire   +3 more sources

Role of CD1d in Coxsackievirus B3-Induced Myocarditis [PDF]

The Journal of Immunology, 2003
Abstract The myocarditic (H3) variant of Coxsackievirus B3 (CVB3) causes severe myocarditis in BALB/c mice and BALB/c mice lacking the invariant Jα281 gene, but minimal disease in BALB/c CD1d−/− animals. This indicates that CD1d expression is important in this disease but does not involve the invariant NKT cell often associated with CD1d-
Huber, Sally, Sartini, Danielle, Exley, Mark   +2 more
openaire   +3 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source