Results 41 to 50 of about 12,093 (219)

Induction of cytopathic effect and cytokines in coxsackievirus B3-infected murine astrocytes [PDF]

, 2013
BACKGROUND: Coxsackievirus commonly infects children and occasionally causes severe meningitis and/or encephalitis in the newborn. The underlying mechanism(s) behind the central nervous system pathology is poorly defined. METHODS: It is hypothesized that
Dangui Zhang, Gang Xin, Gefei Wang, Jun Zeng, Kangsheng Li, Weizhong Li, Xiaoxuan Chen, Zhiwu Jiang   +7 more
core   +1 more source

Amiloride Derivatives Inhibit Coxsackievirus B3 RNA Replication [PDF]

Journal of Virology, 2008
ABSTRACT Amiloride derivatives are known blockers of the cellular Na + /H + exchanger and the epithelial Na + channel. More recent studies demonstrate that they also inhibit ion channels formed by a number of viral proteins. We previously reported that 5-(
David N, Harrison, Elena V, Gazina, Damian F, Purcell, David A, Anderson, Steven, Petrou   +4 more
openaire   +2 more sources

Coxsackievirus B3 infection induces glycolysis to facilitate viral replication

Frontiers in Microbiology, 2022
Coxsackievirus B3 (CVB3) is a leading cause of viral myocarditis, but no effective treatment strategy against CVB3 is available. Viruses lack an inherent metabolic system and thus depend on host cellular metabolism for their benefit.
Yujie Qian, Yeyi Yang, Wenxiang Qing, Chunyun Li, Min Kong, Zhijuan Kang, Yuanbojiao Zuo, Jiping Wu, Meng Yu, Zuocheng Yang   +9 more
doaj   +1 more source

Proteasomal protein degradation: adaptation of cellular proteolysis with impact on virus-and cytokine-mediated damage of heart tissue during myocarditis [PDF]

, 2018
Viral myocarditis is an inflammation of the heart muscle triggered by direct virus-induced cytolysis and immune response mechanisms with most severe consequences during early childhood.
Agarwal, Ajibade, Aki, Akira, Althof, Althof, Arthur, Banks, Barber, Basler, Basler, Basler, Basler, Bitzer, Blasius, Brehm, Caforio, Cascio, Chen, Chow, Chow, Cooper, Corbin-Lickfett, Cornell, Cornell, Corsten, Dantuma, Davidson, De Bruin, De Verteuil, Delboy, Deng, Deol, Deonarain, Dikic, Dimopoulos, Ebstein, Epelman, Ersching, Esfandiarei, Fehling, Feldman, Flynn, Gaczynska, Gaczynska, Gangaplara, Gao, Gebhard, Ginhoux, Godeny, Godeny, Goldberg, Gomes, Goser, Gray, Groll, Groll, Guillaume, Hallermalm, Hallett, Hayashi, Hayashi, Heaton, Henke, Hensley, Hiraoka, Horwitz, Huber, Ichikawa, Jakel, Jakubzick, Jang, Jaquenod De Giusti, Jenne, Jurk, Kalejta, Kalim, Kaspari, Kawai, Kaya, Kemball, Kemball, Kemball, Kessler, Kincaid, Kindermann, Kirschner, Kisselev, Kitamura, Klingel, Klingel, Klingel, Kloetzel, Koerner, Kuhl, Kuhl, La Frazia, Lam, Leipner, Leuschner, Li, Luo, Luo, Macagno, Magrini, Maier, Matsuzaki, Mccarthy, Mccarthy, Mcnab, Mena, Mena, Mercer, Miller, Mishto, Moebius, Muchamuel, Mundt, Mundt, Murata, Murata, Murata, Nebuloni, Nencioni, Neumann, Neznanov, Nussbaum, Opavsky, Opitz, Paeschke, Parlati, Pickart, Pickering, Prösch, Rahnefeld, Rahnefeld, Respondek, Richardson, Richardson, Ronkina, Ros, Rose, Rovere, Runnels, Sagar, Satheshkumar, Scheffner, Schmidt, Schubert, Schwarz, Seifert, Sijts, Spur, Stetson, Stewart, Strehl, Sula Karreci, Szalay, Szalay, Takeda, Takemoto, Tewari, Tian, Triantafilou, Tu, Turnell, Vachharajani, Vankaer, Visekruna, Voigt, Weinzierl, Wessely, Widjaja, Xu, Yun, Zimmermann   +175 more
core   +1 more source

Bilateral idiopathic retinal vasculitis following coxsackievirus A4 infection: a case report

BMC Ophthalmology, 2017
Background Coxsackieviruses are members of a group of viruses called the enteroviruses, which may cause respiratory and gastrointestinal symptoms, erythema, meningoencephalitis, myocarditis, pericarditis, and myositis.
Izumi Mine, Manzo Taguchi, Yutaka Sakurai, Masaru Takeuchi   +3 more
doaj   +1 more source

Dynamic remodelling of the human host cell proteome and phosphoproteome upon enterovirus infection

Nature Communications, 2020
Here, Giansanti et al. perform a system-wide and time-resolved characterization of the changes in the host cell proteome and phosphoproteome of cells infected with the enterovirus coxsackievirus B3 during a full round of replication and identify mTORC1 ...
Piero Giansanti, Jeroen R. P. M. Strating, Kyra A. Y. Defourny, Ieva Cesonyte, Alexia M. S. Bottino, Harm Post, Ekaterina G. Viktorova, Vien Quang Tri Ho, Martijn A. Langereis, George A. Belov, Esther N. M. Nolte-‘t Hoen, Albert J. R. Heck, Frank J. M. van Kuppeveld   +12 more
doaj   +1 more source

Ubiquitination is required for effective replication of coxsackievirus B3. [PDF]

PLoS ONE, 2008
BACKGROUND: Protein ubiquitination and/or degradation by the ubiquitin/proteasome system (UPS) have been recognized as critical mechanisms in the regulation of numerous essential cellular functions.
Xiaoning Si, Guang Gao, Jerry Wong, Yahong Wang, Jingchun Zhang, Honglin Luo   +5 more
doaj   +1 more source

Levamisole exacerbates coxsackievirus B3-induced murine myocarditis [PDF]

Infection and Immunity, 1983
Levamisole administration to several strains of adolescent mice at the time of or up to 4 days post-inoculation (p.i.) with a myocarditic variant of coxsackievirus B3 (CVB3m) increased the number of myocarditic lesions above that found in CVB3m-inoculated mice.
Gudvangen, R J, Duffey, P S, Paque, R E, Gauntt, C J   +3 more
openaire   +2 more sources

VP1 of Enterovirus 71 Protects Mice Against Enterovirus 71 and Coxsackievirus B3 in Lethal Challenge Experiment

Frontiers in Immunology, 2019
Enterovirus and Coxsackievirus are the major viruses that cause hand, foot, and mouth disease (HFMD) outbreaks worldwide. Several studies have shown the potential of viral envelope protein 1 (VP1) on providing protective effects from viral strains of ...
Fang-Hong Chen, Fang-Hong Chen, Xiong Liu, Xiong Liu, Hua-Li Fang, Hua-Li Fang, Nan Nan, Zhan Li, Nian-Zhi Ning, De-Yan Luo, Tao Li, Hui Wang, Hui Wang   +12 more
doaj   +1 more source

Treatment Trends of Myocarditis with Coxsackievirus B3 infection

Al-Mustansiriyah Journal of Pharmaceutical Sciences, 2020
Viral myocarditis occurred after viral invasion of the cardiocytes and followed by the releasing of viral particles and inflammatory cells. Acute viral myocarditis is relatively common phase of the disease cured spontaneously in some cases or leading to
Dalya Basil Hanna, Ghaith Ali Jasim, Arwa Mujahid Abdullah Al-Shuwaikh   +2 more
doaj   +1 more source