Results 31 to 40 of about 69,182 (204)

Short hairpin RNA targeting 2B gene of coxsackievirus B3 exhibits potential antiviral effects both in vitro and in vivo

open access: yesBMC Infectious Diseases, 2012
Background Coxsackievirus B3 is an important infectious agent of viral myocarditis, pancreatitis and aseptic meningitis, but there are no specific antiviral therapeutic reagents in clinical use.
Yao Hailan   +7 more
doaj   +1 more source

The Evolution of Pleconaril: Modified O-Alkyl Linker Analogs Have Biological Activity towards Coxsackievirus B3 Nancy

open access: yesMolecules, 2020
Coxsackieviruses type B are one of the most common causes of mild upper respiratory and gastrointestinal illnesses. At the time of writing, there are no approved drugs for effective antiviral treatment for Coxsackieviruses type B.
Alexandrina Volobueva   +5 more
doaj   +1 more source

Coxsackievirus B3 Exploits the Ubiquitin-Proteasome System to Facilitate Viral Replication

open access: yesViruses, 2021
Infection by RNA viruses causes extensive cellular reorganization, including hijacking of membranes to create membranous structures termed replication organelles, which support viral RNA synthesis and virion assembly.
Martin Voss   +4 more
doaj   +1 more source

Coxsackievirus B3 Responds to Polyamine Depletion via Enhancement of 2A and 3C Protease Activity

open access: yesViruses, 2019
Polyamines are small positively-charged molecules abundant in eukaryotic cells that are crucial to RNA virus replication. In eukaryotic cells, polyamines facilitate processes such as transcription, translation, and DNA replication, and viruses similarly ...
Courtney N. Dial   +3 more
doaj   +1 more source

Coxsackievirus B3-associated panuveitis. [PDF]

open access: yesBritish Journal of Ophthalmology, 1993
A 29-year-old woman suffered from headaches, diarrhoea, and high grade fever followed by a unilateral retinal vasculitis, papillitis, and chorioretinitis. Abnormal electrocardiographic findings and antibody titre dynamics strongly suggested a coxsackievirus B3 infection.
W, Förster, A A, Bialasiewicz, H, Busse
openaire   +2 more sources

Infectious Entry Pathway of Enterovirus B Species

open access: yesViruses, 2015
Enterovirus B species (EV-B) are responsible for a vast number of mild and serious acute infections. They are also suspected of remaining in the body, where they cause persistent infections contributing to chronic diseases such as type I diabetes. Recent
Varpu Marjomäki   +2 more
doaj   +1 more source

Molecular epidemiology of Coxsackievirus B3

open access: yesInfection, Genetics and Evolution, 2010
Molecular epidemiological characteristics are needed to understand the impact of Coxsackievirus B3 (CV-B3) infection, since no CV-B3 genotyping literature is available. Twenty-nine CV-B3 Taiwan strains obtained from 1992 to 2005 were analyzed. A phylogenetic tree was constructed based on the 290 nucleotide sequence of the VP1 gene of Taiwan isolates ...
Pei-Yu, Chu   +11 more
openaire   +2 more sources

Early Treatment of Coxsackievirus B3–Infected Animals With Soluble Coxsackievirus-Adenovirus Receptor Inhibits Development of Chronic Coxsackievirus B3 Cardiomyopathy [PDF]

open access: yesCirculation: Heart Failure, 2019
Background: Coxsackie-B-viruses (CVB) are frequent causes of acute myocarditis and dilated cardiomyopathy, but an effective antiviral therapy is still not available. Previously, we and others have demonstrated that treatment with an engineered sCAR-Fc (soluble coxsackievirus-adenovirus receptor fused to the carboxyl-terminus of
Sandra, Pinkert   +10 more
openaire   +2 more sources

Seroprevalence of Coxsackievirus B3 in Yantai, China

open access: yesJapanese Journal of Infectious Diseases, 2013
Coxsackievirus B3 (CVB3) is an important human pathogen, which is frequently associated with aseptic meningitis and encephalitis in many parts of the world. However, the seroprevalence of this viral infection in China is not well understood; therefore, in the present study, we conducted a serological survey in which 373 serum samples obtained from ...
Tao, Zexin   +8 more
openaire   +3 more sources

Syntheses, Characterizations, and Inhibition Activities Against Coxsackievirus B3 of Iodobenzoic Hydrazide Functionalized Hexamolybdates

open access: yesFrontiers in Chemistry, 2022
A class of iodobenzoyldiazenido-functionalized POMs (TBA)3 [Mo6O18(=N=NCOAr)] (Ar = Ph-o-I (1); Ph-m-I (2); Ph-p-I (3); Ph-3,4-I2(4); Ph-2,3,5-I3(5) (TBA = tetrabutylammonium) were prepared via the refluxing reaction of α-octamolybdates, DCC, and ...
Long-Sheng Wang   +10 more
doaj   +1 more source

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