Results 31 to 40 of about 12,093 (219)

Short hairpin RNA targeting 2B gene of coxsackievirus B3 exhibits potential antiviral effects both in vitro and in vivo

open access: yesBMC Infectious Diseases, 2012
Background Coxsackievirus B3 is an important infectious agent of viral myocarditis, pancreatitis and aseptic meningitis, but there are no specific antiviral therapeutic reagents in clinical use.
Yao Hailan   +7 more
doaj   +1 more source

Coxsackievirus B3 Exploits the Ubiquitin-Proteasome System to Facilitate Viral Replication

open access: yesViruses, 2021
Infection by RNA viruses causes extensive cellular reorganization, including hijacking of membranes to create membranous structures termed replication organelles, which support viral RNA synthesis and virion assembly.
Martin Voss   +4 more
doaj   +1 more source

Coxsackievirus B3 Responds to Polyamine Depletion via Enhancement of 2A and 3C Protease Activity

open access: yesViruses, 2019
Polyamines are small positively-charged molecules abundant in eukaryotic cells that are crucial to RNA virus replication. In eukaryotic cells, polyamines facilitate processes such as transcription, translation, and DNA replication, and viruses similarly ...
Courtney N. Dial   +3 more
doaj   +1 more source

Inhibition of cellular protein secretion by norwalk virus nonstructural protein p22 requires a mimic of an endoplasmic reticulum export signal. [PDF]

open access: yes, 2013
Protein trafficking between the endoplasmic reticulum (ER) and Golgi apparatus is central to cellular homeostasis. ER export signals are utilized by a subset of proteins to rapidly exit the ER by direct uptake into COPII vesicles for transport to the ...
Crawford, Sue E.   +4 more
core   +2 more sources

Infectious Entry Pathway of Enterovirus B Species

open access: yesViruses, 2015
Enterovirus B species (EV-B) are responsible for a vast number of mild and serious acute infections. They are also suspected of remaining in the body, where they cause persistent infections contributing to chronic diseases such as type I diabetes. Recent
Varpu Marjomäki   +2 more
doaj   +1 more source

Central nervous system infection following vertical transmission of Coxsackievirus B4 in mice [PDF]

open access: yes, 2016
This is the author accepted manuscript. The final version is available from the publisher via the DOI in this record.Coxsackie B viruses (CV-B) are important pathogens associated with several central nervous system (CNS) disorders.
Aouni, M   +9 more
core   +1 more source

Molecular epidemiology of Coxsackievirus B3

open access: yesInfection, Genetics and Evolution, 2010
Molecular epidemiological characteristics are needed to understand the impact of Coxsackievirus B3 (CV-B3) infection, since no CV-B3 genotyping literature is available. Twenty-nine CV-B3 Taiwan strains obtained from 1992 to 2005 were analyzed. A phylogenetic tree was constructed based on the 290 nucleotide sequence of the VP1 gene of Taiwan isolates ...
Pei-Yu, Chu   +11 more
openaire   +2 more sources

Mesenchymal stromal cells inhibit NLRP3 inflammasome activation in a model of Coxsackievirus B3-induced inflammatory cardiomyopathy [PDF]

open access: yes, 2018
Inflammation in myocarditis induces cardiac injury and triggers disease progression to heart failure. NLRP3 inflammasome activation is a newly identified amplifying step in the pathogenesis of myocarditis.
A Abbate   +43 more
core   +1 more source

Coxsackievirus B3-induced apoptosis and Caspase-3 [PDF]

open access: yesCell Research, 2003
Cell death can be classified into two categories: apoptosis and necrosis. Apoptotic pathway can be either caspase-dependent or caspase-independent. Caspase-independent cytopathic effect (CPE) has been described. In order to evaluate the pattern of HeLa cell death induced by Coxsackievirus B3 (CVB3) and whether apoptosis involves caspase activation, we ...
Jian Ping, Yuan   +6 more
openaire   +2 more sources

Syntheses, Characterizations, and Inhibition Activities Against Coxsackievirus B3 of Iodobenzoic Hydrazide Functionalized Hexamolybdates

open access: yesFrontiers in Chemistry, 2022
A class of iodobenzoyldiazenido-functionalized POMs (TBA)3 [Mo6O18(=N=NCOAr)] (Ar = Ph-o-I (1); Ph-m-I (2); Ph-p-I (3); Ph-3,4-I2(4); Ph-2,3,5-I3(5) (TBA = tetrabutylammonium) were prepared via the refluxing reaction of α-octamolybdates, DCC, and ...
Long-Sheng Wang   +10 more
doaj   +1 more source

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