Results 31 to 40 of about 8,213 (208)
Role of CD1d in Coxsackievirus B3-Induced Myocarditis [PDF]
The Journal of Immunology, 2003 Abstract The myocarditic (H3) variant of Coxsackievirus B3 (CVB3) causes severe myocarditis in BALB/c mice and BALB/c mice lacking the invariant Jα281 gene, but minimal disease in BALB/c CD1d−/− animals. This indicates that CD1d expression is important in this disease but does not involve the invariant NKT cell often associated with ...
Huber, Sally +2 more
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The structure of coxsackievirus B3 at 3.5 å resolution [PDF]
Structure, 1995 Group B coxsackieviruses (CVBs) are etiologic agents of a number of human diseases that range in severity from asymptomatic to lethal infections. They are small, single-stranded RNA icosahedral viruses that belong to the enterovirus genus of the picornavirus family. Structural studies were initiated in light of the information available on the cellular
Muckelbauer, Jodi K +7 more
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Molecular epidemiology of Coxsackievirus B3
Infection, Genetics and Evolution, 2010 Molecular epidemiological characteristics are needed to understand the impact of Coxsackievirus B3 (CV-B3) infection, since no CV-B3 genotyping literature is available. Twenty-nine CV-B3 Taiwan strains obtained from 1992 to 2005 were analyzed. A phylogenetic tree was constructed based on the 290 nucleotide sequence of the VP1 gene of Taiwan isolates ...
Pei-Yu, Chu +11 more
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Magnetic Resonance Imaging Features of Pediatric Coxsackievirus Encephalitis
Journal of the Belgian Society of Radiology, 2019 Coxsackievirus, a common pathogen causing pediatric infection, typically causes a mild, nonspecific illness with low-grade fever, but can cause severe illness on rare occasions.
Yang-Kai Fan, Yu-Peng Liu
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Molecules, 2020 Coxsackieviruses type B are one of the most common causes of mild upper respiratory and gastrointestinal illnesses. At the time of writing, there are no approved drugs for effective antiviral treatment for Coxsackieviruses type B.
Alexandrina Volobueva +5 more
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Coxsackievirus B3 Replication and Pathogenesis
Future Microbiology, 2015 Viruses such as coxsackievirus B3 (CVB3) are entirely host cell-dependent parasites. Indeed, they must cleverly exploit various compartments of host cells to complete their life cycle, and consequently launch disease. Evolution has equipped this pico-rna-virus, CVB3, to use different strategies, including CVB3-induced direct damage to host cells ...
Farshid S, Garmaroudi +7 more
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BMC Infectious Diseases, 2012 Background Coxsackievirus B3 is an important infectious agent of viral myocarditis, pancreatitis and aseptic meningitis, but there are no specific antiviral therapeutic reagents in clinical use.
Yao Hailan +7 more
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MOPS and coxsackievirus B3 stability
Virology, 2017 Study of coxsackievirus B3 strain 28 (CVB3/28) stability using MOPS to improve buffering in the experimental medium revealed that MOPS (3-morpholinopropane-1-sulfonic acid) increased CVB3 stability and the effect was concentration dependent. Over the pH range 7.0-7.5, virus stability was affected by both pH and MOPS concentration.
Steven D, Carson +2 more
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Coxsackievirus B3 Responds to Polyamine Depletion via Enhancement of 2A and 3C Protease Activity
Viruses, 2019 Polyamines are small positively-charged molecules abundant in eukaryotic cells that are crucial to RNA virus replication. In eukaryotic cells, polyamines facilitate processes such as transcription, translation, and DNA replication, and viruses similarly ...
Courtney N. Dial +3 more
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