Results 11 to 20 of about 69,182 (204)
Replicase gene of coxsackievirus B3
Journal of Virology, 1984 A cDNA copy covering two-thirds of the coxsackievirus B3 genome was cloned in the PstI site of the pBR322 vector. A nucleotide sequence containing the gene for the viral replicase and the 3' noncoding region of the coxsackievirus B3 genome was determined.
P O, Stålhandske +2 more
core +12 more sources
Coxsackievirus B3—Its Potential as an Oncolytic Virus [PDF]
Viruses, 2021 Oncolytic virotherapy represents one of the most advanced strategies to treat otherwise untreatable types of cancer. Despite encouraging developments in recent years, the limited fraction of patients responding to therapy has demonstrated the need to ...
Anja Geisler +4 more
doaj +7 more sources
Virology, 1987 The entire nucleotide sequence of the coxsackievirus B3 strain Nancy (CB3) genome has been determined from cDNA. The genome is 7396 nucleotides long, and encodes a 2185 amino acid long polyprotein. It exhibits the same gene organization as other enterovirus genomes.
A M, Lindberg +2 more
openaire +3 more sources
Interaction of Decay-Accelerating Factor with Coxsackievirus B3 [PDF]
Journal of Virology, 2007 ABSTRACTMany entero-, parecho-, and rhinoviruses use immunoglobulin (Ig)-like receptors that bind into the viral canyon and are required to initiate viral uncoating during infection. However, some of these viruses use an alternative or additional receptor that binds outside the canyon.
Susan, Hafenstein +6 more
openaire +3 more sources
Development of antiviral therapeutics combating coxsackievirus type B3 infection [PDF]
Инфекция и иммунитет, 2021 Enteroviruses comprise highly diverse group of single-stranded positive RNA viruses belonging to Enterovirus genus, Picornaviridae family. They are the most prevalent viruses worldwide highlighted by high resistance to environmental cues.
A. S. Volobueva +2 more
doaj +2 more sources
Major Persistent 5′ Terminally Deleted Coxsackievirus B3 Populations in Human Endomyocardial Tissues
Emerging Infectious Diseases, 2016 We performed deep sequencing analysis of the enterovirus 5′ noncoding region in cardiac biopsies from a patient with dilated cardiomyopathy. Results displayed a mix of deleted and full-length coxsackievirus B3, characterized by a low viral RNA load (8 ...
Alexis Bouin +7 more
doaj +2 more sources
Ubiquitination is required for effective replication of coxsackievirus B3. [PDF]
PLoS ONE, 2008 BACKGROUND: Protein ubiquitination and/or degradation by the ubiquitin/proteasome system (UPS) have been recognized as critical mechanisms in the regulation of numerous essential cellular functions.
Xiaoning Si +5 more
doaj +4 more sources
Treatment Trends of Myocarditis with Coxsackievirus B3 infection [PDF]
Al-Mustansiriyah Journal of Pharmaceutical Sciences, 2020 Viral myocarditis occurred after viral invasion of the cardiocytes and followed by the releasing of viral particles and inflammatory cells. Acute viral myocarditis is relatively common phase of the disease cured spontaneously in some cases or leading to
Dalya Basil Hanna +2 more
doaj +2 more sources
Design of 4-Substituted Sulfonamidobenzoic Acid Derivatives Targeting Coxsackievirus B3
Life, 2022 A series of novel 4-substituted sulfonamidobenzoic acid derivatives was synthesized as the structural evolution of 4-(4-(1,3-dioxoisoindolin-2-yl)phenylsulfonamido)benzoic acid, which is the known inhibitor of the enterovirus life cycle.
Anton A. Shetnev +4 more
doaj +2 more sources
Suppression of Calcium Influx Reduces Coxsackievirus B3 Lethality With Elevated Interferon Beta Responses in Mice. [PDF]
J Med VirolABSTRACT The disease course of severe enterovirus (EV) infection with hepatic necrosis is usually fulminant and fatal. Coxsackievirus (CVB3) is the emerging and important serotype of newborn EV inducing hepatic necrosis. Calcium (Ca2+) regulates host immunity, type I interferon (IFN‐I), and viral infections.
Hsiao YL, Hung CH, Yeh MT, Chen SH.
europepmc +2 more sources