Appendectomy Mitigates Coxsackievirus B3−Induced Viral Myocarditis [PDF]
Viruses, 2023 Appendix has a distinct abundance of lymphatic cells and serves as a reservoir of microbiota which helps to replenish the large intestine with healthy flora.
Chengrui Niu, Wei Xu, Sidong Xiong
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N6-Methyladenosine Positively Regulates Coxsackievirus B3 Replication [PDF]
VirusesEnteroviruses such as coxsackievirus B3 are identified as a common cause of viral myocarditis, but the potential mechanism of its replication and pathogenesis are largely unknown.
Hainian Zhao +9 more
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Coxsackievirus B3—Its Potential as an Oncolytic Virus [PDF]
Viruses, 2021 Oncolytic virotherapy represents one of the most advanced strategies to treat otherwise untreatable types of cancer. Despite encouraging developments in recent years, the limited fraction of patients responding to therapy has demonstrated the need to ...
Anja Geisler +4 more
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CX3CR1 knockout aggravates Coxsackievirus B3-induced myocarditis. [PDF]
PLoS ONE, 2017 Studies on inflammatory disorders elucidated the pivotal role of the CX3CL1/CX3CR1 axis with respect to the pathophysiology and diseases progression. Coxsackievirus B3 (CVB3)-induced myocarditis is associated with severe cardiac inflammation, which may ...
Irene Müller +12 more
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Coxsackievirus B3, Shandong Province, China, 1990–2010
Emerging Infectious Diseases, 2012 To determine the cause of a 2008 outbreak of aseptic meningitis in Shandong Province, China, we analyzed samples from outbreak patients and coxsackievirus B3 samples collected during 1990–2010 surveillance. The cause of the outbreak was coxsackievirus B3,
Zexin Tao +9 more
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ROS-Mediated Necroptosis Promotes Coxsackievirus B3 Replication and Myocardial Injury [PDF]
MicroorganismsCoxsackievirus B3 (CVB3) is a primary causative agent of viral myocarditis (VMC), which can lead to both acute and chronic cardiac inflammation accompanied by progressive heart failure and arrhythmias.
Junbo Huang +9 more
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The protective effects of ivabradine in preventing progression from viral myocarditis to dilated cardiomyopathy [PDF]
Frontiers in Pharmacology, 2016 To study the beneficial effects of ivabradine in dilated cardiomyopathy mice, which evolved from coxsackievirus B3-induced chronic viral myocarditis. Four-to-five-week-old male balb/c mice were inoculated intraperitoneally with coxsackievirus B3 (Strain ...
Li Yue-Chun +8 more
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Comprehensive profiling of neutralizing polyclonal sera targeting coxsackievirus B3 [PDF]
Nature Communications, 2023 Despite their fundamental role in resolving viral infections, our understanding of how polyclonal neutralizing antibody responses target non-enveloped viruses remains limited.
Beatriz Álvarez-Rodríguez +2 more
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IL-9 inhibits viral replication in Coxsackievirus B3-induced myocarditis [PDF]
Frontiers in Immunology, 2016 Myocardial injuries in viral myocarditis (VMC) are caused by viral infection and related autoimmune disorders. Recent studies suggest that IL-9 mediated both antimicrobial immune and autoimmune responses in addition to allergic diseases.
Miao Yu +6 more
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Targeting Viperin prevents coxsackievirus B3-induced acute heart failure [PDF]
Cell DiscoveryCoxsackievirus B3 (CVB3)-induced acute heart failure (AHF) is a common cause of cardiogenic death in young- and middle-aged people. However, the key molecular events linking CVB3 to AHF remain largely unknown, resulting in a lack of targeted therapy ...
Yukang Yuan +21 more
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