Results 21 to 30 of about 69,182 (204)

The neddylation of the RNA-dependent RNA polymerase 3D of Coxsackievirus B3 promotes viral replication. [PDF]

J Virol
The dataset is included all Western blot images, RT-qPCR, TCID50 data for "The neddylation of the RNA-dependent RNA polymerase 3D of Coxsackievirus B3 promotes viral replication"
Li S, Dong Y, Wang X, Feng D, Luan T, Wang Z, Lin L, Chen Y, Wang Y, Fei Y, Wang Y, Zhong Z, Zhao W.   +12 more
europepmc   +2 more sources

Identification of Drug Repurposing Candidates for Coxsackievirus B3 Infection in iPSC-Derived Brain-like Endothelial Cells. [PDF]

Int J Mol Sci
The enterovirus Coxsackievirus B3 causes a range of serious health problems, including aseptic meningitis, myocarditis, and pancreatitis. Currently, Coxsackievirus B3 has no targeted antiviral treatments or vaccines, leaving supportive care as the ...
Wood JF, Vergis JM, Imami AS, Ryan WG, Sin JJ, Kim BJ, Schiefer IT, McCullumsmith RE.   +7 more
europepmc   +2 more sources

Update on coxsackievirus B3 myocarditis [PDF]

Current Opinion in Rheumatology, 2012
To present recent findings on the pathogenesis of coxsackievirus B3 (CVB3) myocarditis based on animal models, with a focus on the role of T helper (Th) immune responses in disease progression.Acute CVB3 myocarditis is known to be increased by Th1 immune responses, but recent findings indicate that Th1-type immunity protects against acute myocarditis ...
DeLisa, Fairweather, Katelyn A, Stafford, Yoon K, Sung   +2 more
openaire   +2 more sources

Comparison of effects of ivabradine versus carvedilol in murine model with the Coxsackievirus B3-induced viral myocarditis. [PDF]

PLoS ONE, 2012
BACKGROUND: Elevated heart rate is associated with increased cardiovascular morbidity. The selective I(f) current inhibitor ivabradine reduces heart rate without affecting cardiac contractility, and has been shown to be cardioprotective in the failing ...
Li Yue-Chun, Zhang Teng, Zhou Na-Dan, Ge Li-Sha, Luo Qin, Guan Xue-Qiang, Lin Jia-Feng   +6 more
doaj   +1 more source

CVB3 Inhibits NLRP3 Inflammasome Activation by Suppressing NF-κB Pathway and ROS Production in LPS-Induced Macrophages

Viruses, 2023
Inflammasomes are cytosolic sensors of pathogens. Their activation can lead to the induction of caspase-1-mediated inflammatory responses and the release of several proinflammatory cytokines, including IL-1β. There is a complex relationship between viral
Yanqi Wang, Zhirong Sun, Hongkai Zhang, Yahui Song, Yi Wang, Wei Xu, Min Li   +6 more
doaj   +1 more source

Coxsackievirus B3, Shandong Province, China, 1990–2010

Emerging Infectious Diseases, 2012
To determine the cause of a 2008 outbreak of aseptic meningitis in Shandong Province, China, we analyzed samples from outbreak patients and coxsackievirus B3 samples collected during 1990–2010 surveillance. The cause of the outbreak was coxsackievirus B3,
Zexin Tao, Yanyan Song, Yan Li, Yao Liu, Ping Jiang, Xiaojuan Lin, Guifang Liu, Lizhi Song, Haiyan Wang, Aiqiang Xu   +9 more
doaj   +1 more source

Enhancement of coxsackievirus B3 infection by antibody to a different coxsackievirus strain [PDF]

Journal of General Virology, 2002
Group B coxsackieviruses (CVBs) are a major cause of viral myocarditis and pancreatitis in humans and produce a similar pattern of disease in inbred strains of mice. As there are six strains of CVBs, individuals can be infected with multiple serotypes.
Jaskamal, Girn, Mojgan, Kavoosi, Janet, Chantler   +2 more
openaire   +2 more sources

Role of CD1d in Coxsackievirus B3-Induced Myocarditis [PDF]

The Journal of Immunology, 2003
Abstract The myocarditic (H3) variant of Coxsackievirus B3 (CVB3) causes severe myocarditis in BALB/c mice and BALB/c mice lacking the invariant Jα281 gene, but minimal disease in BALB/c CD1d−/− animals. This indicates that CD1d expression is important in this disease but does not involve the invariant NKT cell often associated with ...
Huber, Sally, Sartini, Danielle, Exley, Mark   +2 more
openaire   +3 more sources

Coxsackievirus B3 Replication and Pathogenesis

Future Microbiology, 2015
Viruses such as coxsackievirus B3 (CVB3) are entirely host cell-dependent parasites. Indeed, they must cleverly exploit various compartments of host cells to complete their life cycle, and consequently launch disease. Evolution has equipped this pico-rna-virus, CVB3, to use different strategies, including CVB3-induced direct damage to host cells ...
Farshid S, Garmaroudi, David, Marchant, Reid, Hendry, Honglin, Luo, Decheng, Yang, Xin, Ye, Junyan, Shi, Bruce M, McManus   +7 more
openaire   +2 more sources

MOPS and coxsackievirus B3 stability

Virology, 2017
Study of coxsackievirus B3 strain 28 (CVB3/28) stability using MOPS to improve buffering in the experimental medium revealed that MOPS (3-morpholinopropane-1-sulfonic acid) increased CVB3 stability and the effect was concentration dependent. Over the pH range 7.0-7.5, virus stability was affected by both pH and MOPS concentration.
Steven D, Carson, Susan, Hafenstein, Hyunwook, Lee   +2 more
openaire   +2 more sources