Fulminant Type 1 Diabetes Mellitus With Concomitant Coxsackievirus B6 Antibody Elevation and RNA-Based COVID-19 Vaccination: A Case Report and Review of the Literature. [PDF]
ABSTRACT Fulminant type 1 diabetes is a rare but severe condition that can develop rapidly, often in association with viral infections. In this case, coxsackievirus B6 antibody levels were elevated after disease onset, though its significance remains unclear.
Minami H+10 more
europepmc +2 more sources
Outbreak of Enterovirus D68 in Young Children, Brescia, Italy, August to November 2024. [PDF]
ABSTRACT Enterovirus D68 (EV‐D68) is responsible for a plethora of clinical manifestations ranging from asymptomatic infections to severe respiratory symptoms and neurological disorders. EV‐D68 was first detected in children with pneumonia in 1962 and, from then, only sporadic cases were reported until 2014, when outbreaks were notified across the ...
Messali S+9 more
europepmc +2 more sources
Pharmacological and biological antiviral therapeutics for cardiac coxsackievirus infections. [PDF]
Subtype B coxsackieviruses (CVB) represent the most commonly identified infectious agents associated with acute and chronic myocarditis, with CVB3 being the most common variant. Damage to the heart is induced both directly by virally mediated cell destruction and indirectly due to the immune and autoimmune processes reacting to virus infection.
Fechner H+4 more
europepmc +5 more sources
Coxsackievirus Infection and Associated Diseases
Coxsackieviruses (CV) are ubiquitous and widespread single-stranded RNA viruses belonging to the Picornaviridae family and the genus Enterovirus, which also includes poliovirus (PV), the best known of the enteroviruses (EV) [...]
Magloire Pandoua Nekoua, Didier Hober
openaire +5 more sources
Autophagy in coxsackievirus-infected neurons [PDF]
Autophagy is a process to engulf aberrant organelles or protein aggregates into double-membrane vesicles for lysosomal breakdown. Autophagy is a protective process against some intracellular bacteria and viruses; however, it is also used for replication by some viruses, such as poliovirus.
Jung Eun Choi+5 more
openaire +3 more sources
Myocarditis, disseminated infection, and early viral persistence following experimental coxsackievirus B infection of cynomolgus monkeys. [PDF]
Coxsackievirus B (CVB) infection is a common cause of acute viral myocarditis. The clinical presentation of myocarditis caused by this enterovirus is highly variable, ranging from mildly symptoms to complete hemodynamic collapse.
Blanchard, James+7 more
core +5 more sources
Enhancement of coxsackievirus B3 infection by antibody to a different coxsackievirus strain [PDF]
Group B coxsackieviruses (CVBs) are a major cause of viral myocarditis and pancreatitis in humans and produce a similar pattern of disease in inbred strains of mice. As there are six strains of CVBs, individuals can be infected with multiple serotypes.
J. K. Chantler+2 more
openaire +3 more sources
A battle between host and pathogen : the innate immune response and enterovirus evasion strategies [PDF]
Infections with Coxsackieviruses are common and in most cases the infection is asymptomatic and efficiently cleared. On rare occasions, however, an infection can lead to severe diseases including myocarditis, hepatitis and ...
Lind, Katharina
core +3 more sources
Coxsackie B2 Virus Infection Causing Multiorgan Failure and Cardiogenic Shock in a 42-Year-Old Man [PDF]
Infections from coxsackie B2 viruses often cause viral myocarditis and, only rarely, multisystem organ impairment. We present the unusual case of a 42-year-old man in whom coxsackie B2 virus infection caused multiorgan infection, necessitating distal ...
Abdou, Mahmoud H.+2 more
core +1 more source
Modeling viral infectious diseases and development of antiviral therapies using human induced pluripotent stem cell-derived systems [PDF]
The recent biotechnology breakthrough of cell reprogramming and generation of induced pluripotent stem cells (iPSCs), which has revolutionized the approaches to study the mechanisms of human diseases and to test new drugs, can be exploited to generate ...
Barzon, Luisa+6 more
core +2 more sources