Results 21 to 30 of about 195 (85)

Aktivierung von Metallkomplexen durch Ultraschallwellen für eine gezielte Krebstherapie

Angewandte Chemie, EarlyView.
Ultrasound enables non‐invasive activation of metal‐based therapeutics deep within tumors. Acoustic cavitation can drive sonodynamic reactive oxygen species generation or mechanochemical metal–ligand bond dissociation, enabling controlled release of bioactive payloads.
Félix Grosjean, Nicolás Montesdeoca, Gilles Berger, Johannes Karges   +3 more
wiley   +1 more source

Activation of Metal Complexes With Ultrasound Waves for Targeted Anticancer Therapy

Angewandte Chemie International Edition, EarlyView.
Ultrasound enables non‐invasive activation of metal‐based therapeutics deep within tumors. Acoustic cavitation can drive sonodynamic reactive oxygen species generation or mechanochemical metal–ligand bond dissociation, enabling controlled release of bioactive payloads.
Félix Grosjean, Nicolás Montesdeoca, Gilles Berger, Johannes Karges   +3 more
wiley   +1 more source

Serum Krebs von den Lungen-6 as a potential biomarker for distinguishing combined pulmonary fibrosis and emphysema from chronic obstructive pulmonary disease: A retrospective study

Heliyon
Background: The presence of fibrotic interstitial lung disease (ILD) is relatively common in patients with emphysema. This has been designated combined pulmonary fibrosis and emphysema (CPFE). CPFE had worse prognosis than emphysema alone.
Aiyuan Zhou, Xiyan Zhang, Rongli Lu, Wenzhong Peng, Yanan Wang, Haiyun Tang, Pinhua Pan   +6 more
doaj   +1 more source

Improvement of pulmonary arterial compliance by pulmonary vasodilator in pulmonary hypertension from combined pulmonary fibrosis and emphysema

Respiratory Medicine Case Reports, 2019
Combined pulmonary fibrosis and emphysema (CPFE) is a common but under-recognized syndrome characterized with distinct profiles of both pulmonary fibrosis and emphysema.
Kei Kusaka, Yoshiteru Morio, Yuya Kimura, Keita Takeda, Masahiro Kawashima, Kimihiko Masuda, Hirotoshi Matsui   +6 more
doaj   +1 more source

Serum Levels of Surfactant Proteins in Patients with Combined Pulmonary Fibrosis and Emphysema (CPFE). [PDF]

PLoS ONE, 2016
Emphysema and idiopathic pulmonary fibrosis (IPF) present either per se or coexist in combined pulmonary fibrosis and emphysema (CPFE). Serum surfactant proteins (SPs) A, B, C and D levels may reflect lung damage.
Andriana I Papaioannou, Konstantinos Kostikas, Effrosyni D Manali, Georgia Papadaki, Aneza Roussou, Aris Spathis, Argyro Mazioti, Ioannis Tomos, Ilias Papanikolaou, Stelios Loukides, Kyriakos Chainis, Petros Karakitsos, Matthias Griese, Spyros Papiris   +13 more
doaj   +1 more source

Clinical Outcomes and Acute Exacerbation Incidence in Combined Pulmonary Fibrosis and Emphysema

Respirology, EarlyView.
This multicentre prospective study of 1016 patients demonstrated that CPFE, defined as ≥ 5% emphysema on visual CT assessment, identified a high‐risk phenotype with significantly worse 5‐year survival compared to non‐CPFE IIP patients (51.4% vs. 63.1%) and COPD patients (51.4% vs. 84.0%) and higher acute exacerbation incidence, validating international
Kazuya Tsubouchi, Yasuaki Kotetsu, Tomotsugu Takano, Hiroaki Ogata, Fumiaki Kiyomi, Katsuyuki Ichiki, Shohei Takata, Yasuhiko Kitasato, Hiroshi Ishii, Kazuhiro Yatera, Kei Yamasaki, Masaki Okamoto, Makoto Yoshida, Masayuki Kawasaki, Masaki Fujita, Tomohiro Ogawa, Kazunori Tobino, Eiji Harada, Noriaki Nakagaki, Masashi Komori, Taishi Harada, Hiroshi Wataya, Yoichi Nakanishi, Isamu Okamoto   +23 more
wiley   +1 more source

Use of machine learning models to predict prognosis of combined pulmonary fibrosis and emphysema in a Chinese population

BMC Pulmonary Medicine, 2022
Background Combined pulmonary fibrosis and emphysema (CPFE) is a novel clinical entity with a poor prognosis. This study aimed to develop a clinical nomogram model to predict the 1-, 2- and 3-year mortality of patients with CPFE by using the machine ...
Qing Liu, Di Sun, Yu Wang, Pengfei Li, Tianci Jiang, Lingling Dai, Mengjie Duo, Ruhao Wu, Zhe Cheng   +8 more
doaj   +1 more source

Combined Pulmonary Fibrosis and Emphysema: Comparative Evidence on a Complex Condition

Biomedicines, 2023
Combined pulmonary fibrosis and emphysema (CPFE) is a clinical syndrome characterized by upper lobe emphysema and lower lobe fibrosis manifested by exercise hypoxemia, normal lung volumes, and severe reduction of diffusion capacity of carbon monoxide. It
Diana Calaras, Alexander G. Mathioudakis, Zsofia Lazar, Alexandru Corlateanu   +3 more
doaj   +1 more source

High‐Temperature Alloys in Aeroengines: Damage and Fracture Insights From Micromechanical Modeling

cMat, Volume 3, Issue 3, September 2026.
ABSTRACT High‐temperature alloys are the cornerstone of aeroengine hot‐section components, where extreme thermomechanical conditions give rise to intricate damage and fracture behaviors that critically limit the structural integrity of whole aeroengines.
Zixu Guo, Xiaochong Lu, Yuwei Cao, Xuanpeng Lu, Dawei Huang, Xiaojun Yan, Wanlin Guo, Yong‐Wei Zhang, Yilun Xu   +8 more
wiley   +1 more source

Attenuation Levels of Lung Fields in Quantitative Computed Tomography Evaluation Are Associated With Overall Survival and the Incidence of Acute Exacerbation in Combined Pulmonary Fibrosis and Emphysema: A Single‐Center Retrospective Observational Study

Health Science Reports, Volume 9, Issue 9, September 2026.
ABSTRACT Background and Aims Combined pulmonary fibrosis and emphysema (CPFE) is characterized by the coexistence of emphysematous lesions and fibrotic interstitial lung disease. We assessed the relationships of quantitative computed tomography (CT)‐derived measures with clinical characteristics and outcomes in CPFE.
Yusuke Suzuki, Yoshiaki Kitaguchi, Takumi Kinjo, Norihiko Goto, Masamichi Komatsu, Fumika Ueno, Yosuke Wada, Atsuhito Ushiki, Masanori Yasuo, Kiyoyasu Fukushima, Masayuki Hanaoka   +10 more
wiley   +1 more source