Results 51 to 60 of about 318,338 (358)

Maternal BMI as a predictor of methylation of obesity-related genes in saliva samples from preschool-age Hispanic children at-risk for obesity. [PDF]

open access: yes, 2017
BackgroundThe study of epigenetic processes and mechanisms present a dynamic approach to assess complex individual variation in obesity susceptibility. However, few studies have examined epigenetic patterns in preschool-age children at-risk for obesity ...
Barkin, Shari L   +4 more
core   +2 more sources

Two Faces of NOTCH1 in Childhood Lymphoblastic T‐Cell Neoplasia: Prognostic Divergence of Mutational and Structural Aberrations

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT In pediatric patients, T‐cell lymphoblastic lymphoma (T‐LBL) survival exceeds 80%. Relapse remains associated with limited curative options. Frontline treatment is largely extrapolated from T‐cell acute lymphoblastic leukemia (T‐ALL) treatment, reflecting the ongoing debate, whether both entities represent distinct diseases or variants within ...
Marie C. Heider   +4 more
wiley   +1 more source

Workflow for Probabilistic Resource Estimation: Jafurah Basin Case Study (Saudi Arabia)

open access: yesEnergies, 2021
This study provides a workflow and preliminary estimations of the estimated ultimate recovery (EUR) volumes for natural gas and condensate liquids in the Tuwaiq Mountain Formation, the principal target in the Jafurah Field development project in Saudi ...
Ruud Weijermars   +2 more
doaj   +1 more source

Co-delivery of human cancer-testis antigens with adjuvant in protein nanoparticles induces higher cell-mediated immune responses. [PDF]

open access: yes, 2018
Nanoparticles have attracted considerable interest as cancer vaccine delivery vehicles for inducing sufficient CD8+ T cell-mediated immune responses to overcome the low immunogenicity of the tumor microenvironment.
Kim, Tae Il   +5 more
core   +2 more sources

Planar CPG graphs

open access: yesCoRR, 2018
We show that for any $k \geq 0$, there exists a planar graph which is $B_{k+1}$-CPG but not $B_k$-CPG. As a consequence, we obtain that $B_k$-CPG is a strict subclass of $B_{k+1}$-CPG.
Nicolas Champseix   +2 more
openaire   +2 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

A core-based XRF scanning workflow for continuous measurement of mineralogical variations in clastic reservoirs

open access: yesMethodsX, 2022
Clastic reservoir core is routinely characterized using conventional, destructive spot sampling techniques. Whilst spot sampling provides useful textural and compositional information, the samples are typically widely spaced (∼ 25 cm), and hence ...
Arif Hussain, Khalid Al-Ramadan
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

The influence of CpG and UpA dinucleotide frequencies on RNA virus replication and characterization of the innate cellular pathways underlying virus attenuation and enhanced replication [PDF]

open access: yes, 2014
Most RNA viruses infecting mammals and other vertebrates show profound suppression of CpG and UpA dinucleotide frequencies. To investigate this functionally, mutants of the picornavirus, echovirus 7 (E7), were constructed with altered CpG and UpA ...
Atkinson, Nicky J.   +3 more
core   +2 more sources

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Home - About - Disclaimer - Privacy