Results 221 to 230 of about 898,079 (297)

Aberrant CpG Island Methylation of Multiple Genes in Intrahepatic Cholangiocarcinoma [PDF]

open access: green, 2002
Sun Lee   +4 more
openalex   +1 more source

Swatting Flies: Biting Insects as Non‐Invasive Samplers for Mammalian Population Genomics

open access: yesMolecular Ecology, EarlyView.
ABSTRACT Advances in next‐generation sequencing have allowed the use of DNA obtained from unusual sources for wildlife studies. However, these samples have been used predominantly to sequence mitochondrial DNA for species identification while population genetics analyses have been rare.
Anubhab Khan   +10 more
wiley   +1 more source

Genome‐wide DNA methylation profiles in the raphe nuclei of patients with autism spectrum disorder

open access: yesPsychiatry and Clinical Neurosciences, EarlyView.
Aim Autism spectrum disorder (ASD) has a strong genetic basis, yet its genetic complexities remain elusive. Current research highlights environmental factors and epigenetic processes, such as DNA methylation, as crucial in ASD development. This exploratory study addresses a gap in understanding epigenetic regulation in the dorsal raphe (DR)—a region ...
Keiko Iwata   +6 more
wiley   +1 more source

Management of T‐cell malignancies: Bench‐to‐bedside targeting of epigenetic biology

open access: yesCA: A Cancer Journal for Clinicians, EarlyView.
Abstract The peripheral T‐cell lymphomas (PTCL) are the only disease for which four histone deacetylase (HDAC) inhibitors have been approved globally as single agents. Although it is not clear why the PTCL exhibit such a vulnerability to these drugs, understanding the biological basis for this activity is essential.
Ariana Sabzevari   +7 more
wiley   +1 more source

Methyl-CpG-binding protein MBD2 plays a key role in maintenance and spread of DNA methylation at CpG islands and shores in cancer

open access: yesOncogene, 2016
C. Stirzaker   +11 more
semanticscholar   +1 more source

Revolutionizing multi‐omics analysis with artificial intelligence and data processing

open access: yesQuantitative Biology, Volume 13, Issue 3, September 2025.
Abstract Our understanding of intricate biological systems has been completely transformed by the development of multi‐omics approaches, which entail the simultaneous study of several different molecular data types. However, there are many obstacles to overcome when analyzing multi‐omics data, including the requirement for sophisticated data processing
Ali Yetgin
wiley   +1 more source

The SAM domain-containing protein 1 (SAMD1) acts as a repressive chromatin regulator at unmethylated CpG islands. [PDF]

open access: yesSci Adv, 2021
Stielow B   +15 more
europepmc   +1 more source

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