Aberrant CpG Island Methylation of Multiple Genes in Intrahepatic Cholangiocarcinoma [PDF]
Sun Lee+4 more
openalex +1 more source
Swatting Flies: Biting Insects as Non‐Invasive Samplers for Mammalian Population Genomics
ABSTRACT Advances in next‐generation sequencing have allowed the use of DNA obtained from unusual sources for wildlife studies. However, these samples have been used predominantly to sequence mitochondrial DNA for species identification while population genetics analyses have been rare.
Anubhab Khan+10 more
wiley +1 more source
Species-Specific Relationships between DNA and Chromatin Properties of CpG Islands in Embryonic Stem Cells and Differentiated Cells. [PDF]
Langerman J+3 more
europepmc +1 more source
CpG island methylator phenotype is an independent predictor of survival benefit from 5-fluorouracil in stage III colorectal cancer: a new trick for an old dog [PDF]
Marius van Rijnsoever+3 more
openalex +1 more source
Genome‐wide DNA methylation profiles in the raphe nuclei of patients with autism spectrum disorder
Aim Autism spectrum disorder (ASD) has a strong genetic basis, yet its genetic complexities remain elusive. Current research highlights environmental factors and epigenetic processes, such as DNA methylation, as crucial in ASD development. This exploratory study addresses a gap in understanding epigenetic regulation in the dorsal raphe (DR)—a region ...
Keiko Iwata+6 more
wiley +1 more source
Management of T‐cell malignancies: Bench‐to‐bedside targeting of epigenetic biology
Abstract The peripheral T‐cell lymphomas (PTCL) are the only disease for which four histone deacetylase (HDAC) inhibitors have been approved globally as single agents. Although it is not clear why the PTCL exhibit such a vulnerability to these drugs, understanding the biological basis for this activity is essential.
Ariana Sabzevari+7 more
wiley +1 more source
CpG-Islands as Markers for Liquid Biopsies of Cancer Patients. [PDF]
Sprang M, Paret C, Faber J.
europepmc +1 more source
Revolutionizing multi‐omics analysis with artificial intelligence and data processing
Abstract Our understanding of intricate biological systems has been completely transformed by the development of multi‐omics approaches, which entail the simultaneous study of several different molecular data types. However, there are many obstacles to overcome when analyzing multi‐omics data, including the requirement for sophisticated data processing
Ali Yetgin
wiley +1 more source
The SAM domain-containing protein 1 (SAMD1) acts as a repressive chromatin regulator at unmethylated CpG islands. [PDF]
Stielow B+15 more
europepmc +1 more source