Results 111 to 120 of about 783,269 (286)

Post crack flexural toughness in steel fabric and fibre reinforced concrete beams [PDF]

open access: yes, 2008
The purpose of the paper is to provide independent research and evaluate manufacturers’ claims that structural polypropylene fibres provide satisfactory crack control reinforcement and compare the test results from macro synthetic polypropylene fibres ...
Richardson, Alan
core  

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Cracks Cleave Crystals

open access: yes, 2003
The problem of finding what direction cracks should move is not completely solved. A commonly accepted way to predict crack directions is by computing the density of elastic potential energy stored well away from the crack tip, and finding a direction of
Broberg K. B.   +6 more
core   +2 more sources

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

The importance of geomechanics in oil and gas geology and in the processes of opening producing horizons

open access: yesМінеральні ресурси України, 2017
The role of geomechanical factors is shown by the specific examples, particularly the type of stress-strain state (SSS) of rocks on the formation of geological structures with the characteristics of reservoirs or lids, and also technogenic cracks around ...
Yu. I. Voitenko
doaj  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Frecuencia y características de las embarazadas y los recién nacidos expuestos a marihuana y cocaína en la Maternidad del Hospital de Maldonado

open access: yesAnales de la Facultad de Medicina, 2016
El consumo de pasta base de cocaína y marihuana durante el embarazo es un problema creciente. El objetivo de este estudio fue estimar la frecuencia del consumo de estas sustancias durante el embarazo en mujeres hospitalizados en el Hospital de Maldonado ...
María Claudia Cabrera   +5 more
doaj  

La construction du crack comme « problème public ». Socio-histoire des imaginaires sur des publics considérés comme « indésirables » (1986-2023)

open access: yesHistoire, Médecine et Santé
This article aims to trace how crack has been constructed as a “public issue” in France, particularly in the working-class neighborhoods in the North-East of Paris, by adopting a socio-historical perspective from 1986 to 2023.
Marie Jauffret-Roustide
doaj   +1 more source

Home - About - Disclaimer - Privacy