Results 121 to 130 of about 781,009 (287)

Fenòmen. Cracking the crack

, 2010
Peer ...
openaire   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Frecuencia y características de las embarazadas y los recién nacidos expuestos a marihuana y cocaína en la Maternidad del Hospital de Maldonado

Anales de la Facultad de Medicina, 2016
El consumo de pasta base de cocaína y marihuana durante el embarazo es un problema creciente. El objetivo de este estudio fue estimar la frecuencia del consumo de estas sustancias durante el embarazo en mujeres hospitalizados en el Hospital de Maldonado ...
María Claudia Cabrera, María José Pérez, Carlos Zunino, Yohany Cabana, Loreley García, Gustavo Giachetto   +5 more
doaj  

La construction du crack comme « problème public ». Socio-histoire des imaginaires sur des publics considérés comme « indésirables » (1986-2023)

Histoire, Médecine et Santé
This article aims to trace how crack has been constructed as a “public issue” in France, particularly in the working-class neighborhoods in the North-East of Paris, by adopting a socio-historical perspective from 1986 to 2023.
Marie Jauffret-Roustide
doaj   +1 more source

Reversing the telescope:evaluating NGO peer regulation initiatives [PDF]

, 2016
Crack, Angela
core   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Self-healing of Micro-cracks in Engineered Cementitious Composites

Civil Engineering Dimension, 2015
The performance of an Engineered Cementitious Composite (ECC) to self-heal micro-cracks under a controlled laboratory environment is presented. Ten dog-bone shaped samples were prepared; five of them were preloaded to known strains and then left to heal
Suryanto B., Wilson S.A., McCarter W.J.
doaj  

The regulation of international NGOs:assessing the effectiveness of INGO Accountability Charter [PDF]

, 2018
Crack, Angela
core   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

A nonlocal elasticity theory to model the static behaviour of edge-cracked nanobeams

Fracture and Structural Integrity
In the present paper, the mechanical behaviour of edge-cracked nanobeams under Mixed-Mode loading is analytically investigated by means of the Stress-Driven nonlocal model. Firstly, the proposed formulation is outlined, and then applied to the case of a
Daniela Scorza, Andrea Carpinteri, Camilla Ronchei, Andrea Zanichelli, Sabrina Vantadori, Raimondo Luciano   +5 more
doaj   +1 more source