Results 41 to 50 of about 1,306,615 (288)

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Automatic and time-resolved determination of fracture characteristics from in situ experiments

open access: yesMaterials & Design
The characterization of materials in ever smaller dimensions is crucial for the growing demand for miniaturized devices. Hence, in situ fracture experiments are frequently performed at the micron to sub-micron scale. To evaluate fracture process of these
K. Schmuck   +3 more
doaj   +1 more source

Determining mode I cohesive law of Pinus pinaster by coupling double cantilever beam test with digital image correlation [PDF]

open access: yesFracture and Structural Integrity, 2015
The direct identification of the cohesive law in pure mode I of Pinus pinaster is addressed. The approach couples the double cantilever beam (DCB) test with digital image correlation (DIC).
J. Xavier   +3 more
doaj   +1 more source

Calculation of the opening displacement of surface-breaking plane cracks

open access: yesComputer Methods in Applied Mechanics and Engineering, 1992
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Dewynne, J, Hills, D, Nowell, D
openaire   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Test for Crack Opening Displacement of Steel Fiber Reinforced Concrete under Three-Point Bending

open access: yes, 2010
Based on the principle of electrical measurement method, the clip gauge was made to measure the crack opening displacement (COD).Through the three-point bending test on the specimens of steel fiber reinforced high strength concrete (SFHSC), the effect of
Yuan Bao Leng   +2 more
core   +1 more source

Cyclic J-integral using the linear matching method [PDF]

open access: yes, 2013
The extended version of the latest Linear Matching Method (LMM) has the capability to evaluate the stable cyclic response, which produces cyclic stresses, residual stresses and plastic strain ranges for the low cycle fatigue assessment with cyclic load ...
Chen, Haofeng, Chen, Weihang
core   +3 more sources

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

Evolution of residual stress at a fatigue crack tip and its influence on crack tip shielding and plasticity

open access: yesJournal of Materials Research and Technology
The evolution of residual stresses (RS) at a crack tip and associated changes in crack shielding effects during fatigue crack growth (FCG) has a first order effect on the fatigue life of welded joints.
Zhe Zhang   +3 more
doaj   +1 more source

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