Results 61 to 70 of about 66,884 (287)

A new test methodology based on structural resonance for mode I fatigue delamination growth in an unidirectional composite [PDF]

open access: yes, 2013
A specific device has been set up to test by vibration resonance the mode I fatigue delamination growth onset of composite laminates. This test system, based on the DCB test specimen, is a mass-spring-specimen dynamic system designed to resonate.
Fressinet, Mathieu   +4 more
core   +4 more sources

Performance of perforated FRP stub beams subject to static transverse actions [PDF]

open access: yes, 2020
This paper presents an experimental programme designed to investigate the failure mode and ultimate capacity of pultruded glass fibre reinforced polymer (GFRP) cellular profiles subject to transverse loading.
Gand, Alfred   +2 more
core   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

open access: yesMolecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece   +18 more
wiley   +1 more source

Stress-wave analysis technique study on thick-walled type A302B steel pressure vessels, July 1968 - July 1969 [PDF]

open access: yes
Stress wave analysis and crack opening displacement to monitor subcritical crack growth for grade B alloy steel pressure ...
Climent, F. J.   +3 more
core   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

Through-the-thickness fatigue crack closure behavior in an aluminum alloy [PDF]

open access: yes
The variation in fatigue crack closure behavior across the thickness of aluminum alloy specimens was investigated. The specimen geometries examined were the middle crack tension M(T) and compact tension C(T).
Dawicke, D. S.   +2 more
core   +1 more source

Determination of Mode I Fracture Toughness of Cortical Human Bone using the DCB Test [PDF]

open access: yes, 2015
The fracture behaviour of human cortical bone was analysed considering a miniaturized version of theDouble Cantilever Beam (DCB) test. A specific data reduction scheme based on crack equivalentconcept was used to obtain the resistance curves.
F. A. M. Pereira   +8 more
core  

On the numerical modelling of bond for the failure analysis of reinforced concrete [PDF]

open access: yes, 2017
The structural performance of reinforced concrete relies heavily on the bond between reinforcement and concrete. In nonlinear finite element analyses, bond is either modelled by merged, also called perfect bond, or coincident with slip, also called bond ...
Grassl, Peter   +2 more
core   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

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