Results 121 to 130 of about 15,296 (267)

Macronutrient and micronutrient profiles of meat types: insights into human health and diet

Journal of the Science of Food and Agriculture, EarlyView.
Abstract Despite considerable advances in global health and nutrition, emerging challenges such as population growth, climate change, and limited natural resources continue to threaten food security. Meat remains an essential component of the human diet, supplying high‐quality proteins, essential amino acids, lipids, vitamins, and minerals necessary ...
Özgül Anitaş, Serap Göncü, Fatma Hepsağ, Nazan Koluman, Yesim Ozogul   +4 more
wiley   +1 more source

Proteomics of Nitrotyrosine: Integrating Mass Spectrometry and Immunodetection in Redox‐Driven Pathology

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Nitrooxidative stress, driven by excess reactive nitrogen species like peroxynitrite, contributes to the pathogenesis of many chronic diseases. Among its molecular footprints, 3‐nitrotyrosine (3NT) has emerged as a biologically relevant marker of protein nitration.
Brîndușa Alina Petre
wiley   +1 more source

Movement Disorders in Developmental and Epileptic Encephalopathies

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Monogenic developmental and epileptic encephalopathies (DEE) frequently feature co‐occurring movement disorders. Gene discovery has expanded epilepsy‐dyskinesia syndromes (EDS) from classic associations such as stereotypies in Rett syndrome to PRRT2‐related infantile seizures with paroxysmal dyskinesia and crouched gait in SCN1A ...
Shekeeb Mohammad, Darius Ebrahimi‐Fakhari, Hugo Morales‐Briceno   +2 more
wiley   +1 more source

Deciphering the soybean root rot pathogen Phytophthora sojae: Signaling pathways, transcriptional regulation, and effector biology

New Plant Protection, EarlyView.
This review highlights how Phytophthora sojae utilizes unconventional lineage‐specific signaling networks, including unique G protein‐coupled receptor fusions, expanded kinases, and rapidly evolving effectors, to infect soybeans. Understanding these divergent molecular paradigms reveals critical vulnerabilities in this destructive pathogen, offering ...
Min Qiu, Xiaoyi Zhang, Bo Yang, Wenwu Ye, Yuanchao Wang   +4 more
wiley   +1 more source

The skeletal muscle–adipose creatine metabolic axis: A novel paradigm for lipid metabolism reprogramming and obesity management

Experimental Physiology
The global prevalence of obesity and related metabolic disorders has spurred interdisciplinary research to develop new intervention strategies. Current research is increasingly focusing on the exercise‐induced browning of white adipose tissue and the ...
Yuhui Su, Na Liu, Yang Liu, Yiqun Sun, Yike Jiao   +4 more
doaj   +1 more source

Evaluation of SLC6A8 species conservation and the effect of pathogenic variants on creatine transport

HGG Advances
Summary: Creatine phosphate is a high-energy molecule essential for the normal functioning of highly metabolically active organs and tissues. SLC6A8 encodes the only known creatine transporter in humans (CRT1); pathogenic variants result in a ...
Taryn Diep, Gerald S. Lipshutz
doaj   +1 more source

Treatment outcome of creatine transporter deficiency: international retrospective cohort study.

, 2018
peer reviewedTo evaluate the outcome of current treatment for creatine transporter (CRTR) deficiency, we developed a clinical severity score and initiated an international treatment registry.
Lionel van Maldergem, Koeberl, Dwight D, Joost, Kairit, Mercimek-Andrews, Saadet, Salomons, Gajja S., Ounap, Katrin, Koeberl, Dwight D., Bandeira, Anabela O, Sarah Sidky, Dwight D. Koeberl, Gajja S. Salomons, DEBRAY, François-Guillaume, Sidky, Sarah, Bandeira, Anabela O., Anabela O. Bandeira, Bruun, Theodora U. J., Jennifer Goldstein, Theodora U. J. Bruun, van Maldergem, Lionel, Diogo Luísa, Katrin Õunap, Bruun, Theodora U J, O’Sullivan, Siobhan, Marie-Cecile Nassogne, Kairit Joost, Nassogne, Marie-Cecile, O'Sullivan, Siobhan, Saadet Mercimek-Andrews, Debray, Francoise-Guillaume, Can Ficicioglu, Andreas Schulze, Ficicioglu, Can, Goldstein, Jennifer, Salomons, Gajja S, Francoise-Guillaume Debray, Siobhan O’Sullivan, Schulze, Andreas, Luisa, Diogo   +37 more
core   +1 more source

Proteomic Profiling of Myofiber Repair Annexins and Their Role in Duchenne Muscular Dystrophy

PROTEOMICS, EarlyView.
ABSTRACT Myofiber regeneration and membrane repair play crucial roles in maintaining the continuous physiological functioning of the neuromuscular system. A swift and efficient repair mechanism enables the rapid restoration of sarcolemmal integrity following cellular impairment in damaged skeletal muscles.
Paul Dowling, Dounia Bouragba, Elisa Negroni, Capucine Trollet, Margit Zweyer, Dieter Swandulla, Kay Ohlendieck   +6 more
wiley   +1 more source

Treatment of Creatine Transporter (SLC6A8) Deficiency With Oral S-Adenosyl Methionine as Adjunct to L-arginine, Glycine, and Creatine Supplements

, 2015
BACKGROUND: Creatine transporter (SLC6A8) deficiency is an X-linked inborn error of metabolism characterized by cerebral creatine deficiency, behavioral problems, seizures, hypotonia, and intellectual developmental disability.
Mignone, Cristina, Newlove, Theresa, Elango, Rajavel, van Karnebeek, Clara D. M., Jaggumantri, Sravan, Edgar, Vanessa, Collet, Jean Paul, Dunbar, Mary, Sargent, Michael, Stockler-Ipsiroglu, Sylvia   +9 more
core   +1 more source

Cell‐Free Protein Synthesis in Porous Parylene Scaffolds

Small Methods, EarlyView.
The CinPP system, embedding CFPS machineries within porous parylene, is proposed as a novel platform for in vitro protein synthesis, overcoming previous limitations related to processability, structuring integration, and storage stability. By introducing porous parylene as a replacement for aqueous medium via CVD, CinPP paves the way for expanded bio ...
Gunoh Lee, So Jeong Lee, Min‐Jung Park, Hsien‐Yeh Chen, Joerg Lahann, Dong‐Myung Kim, Kyung Jin Lee   +6 more
wiley   +1 more source