Results 181 to 190 of about 26,802 (257)

Epigenetic Modulation of the ACE System Underlies the Slow Aerobic Muscle Phenotype and Metabolic Exercise Response

The FASEB Journal, Volume 40, Issue 6, 31 March 2026.
Weekly moderate‐to‐vigorous activity (≈6 h) induced a marked increase in ACE promoter methylation in exercised knee‐extensor muscle. In combination with the ACE I/D genotype, ACE methylation contributed to ACE gene activity regulation in ways aligning with the slow‐twitch, aerobic muscle phenotype and its metabolic response to endurance exercise ...
Flück Martin, Benedikt Gasser, Giraud Marie‐Noëlle   +2 more
wiley   +1 more source

How a patient-led advocacy organization supports the road to diagnosis and treatment of creatine transporter deficiency. [PDF]

Front Neurosci
Wallis H, Iyer S, Reinhardt EK.
europepmc   +1 more source

Creatine transporter deficiency, an underdiagnosed cause of male intellectual disability. [PDF]

BMJ Case Rep, 2020
Jangid N, Surana P, Salmonos G, Jain V.
europepmc   +1 more source

Navigating the Ethereal Tightrope: The Nanogenerator Manipulates Neurons for Immune Equilibrium

Advanced Science, Volume 13, Issue 14, 9 March 2026.
This review explores how nanogenerators modulate neuroimmune responses, offering innovative strategies for treating neurological disorders. By interfacing with neural pathways, they enable precise control of immune activity, especially via vagus nerve stimulation.
Jia Du, Rui Deng, Ya Wu, Hong‐Xia Ren, Zong‐Hong Lin, Yang‐Bao Miao   +5 more
wiley   +1 more source

Novel Corrector for Variants of SLC6A8: A Therapeutic Opportunity for Creatine Transporter Deficiency. [PDF]

ACS Chem Biol
Gechijian LN, Muncipinto G, Rettenmaier TJ, Labenski MT, Rusu V, Rosskamp L, Conway L, van Kalken D, Gross L, Iantosca G, Crotty W, Mathis R, Park H, Rabin B, Westgate C, Lyons M, Deshusses C, Brandon N, Brown DG, Blanchette HS, Pullen N, Jones LH, Barrish JC.   +22 more
europepmc   +1 more source

X-linked creatine transporter deficiency

, 2014
promotiedatum: 7-3-2014 prom-id ...
openaire   +2 more sources

Iron/Cobalt Dual‐Atom Catalyst Orchestrate Photothermal‐Chemodynamic Immunotherapy Against MRSA: Multi‐Omics Dissection in Murine and Porcine Models

Advanced Science, Volume 13, Issue 14, 9 March 2026.
FeCo dual‐atom catalyst (FeCo‐N‐DAC) with ultrahigh metal loading (Fe > 5.4%, Co > 4.8%) is developed for synergistic photothermal‐chemodynamic immunotherapy. FeCo‐N‐DAC penetrates deep‐seated tissues, eradicates MRSA biofilms, and reprograms immune‐inflammatory pathways via multi‐omics‐validated mechanisms.
Shihao Xu, Binge Huang, Hao Lin, Jinming Li, Zhaoxiang Lu, Qi Zhang, Jia Li, Shiping Yang, Songsong Lan, Yan Yang, Yun Feng, Xiaojun He   +11 more
wiley   +1 more source

Novel translational phenotypes and biomarkers for creatine transporter deficiency. [PDF]

Brain Commun, 2020
Mazziotti R, Cacciante F, Sagona G, Lupori L, Gennaro M, Putignano E, Alessandrì MG, Ferrari A, Battini R, Cioni G, Pizzorusso T, Baroncelli L.   +11 more
europepmc   +1 more source

OCTN2 Activates a Non‐Canonical Carnitine Metabolic Pathway to Promote MASH‐HCC Progression and Immunotherapy Resistance

Advanced Science, Volume 13, Issue 16, 18 March 2026.
In non‐MASH‐HCC, L‐carnitine promotes tumor progression primarily through its classical role in enhancing fatty acid oxidation (FAO). However, in MASH‐HCC, where FAO is markedly suppressed, L‐carnitine shifts from this canonical function to serve instead as an intracellular acetyl group buffer.
Chuqi Xia, Xiao Zhang, Jinze Li, Ning Xu, Sheng Hu, Qiyu Lu, Yuxuan Li, Taifu Xiao, Xu Li, Xue Wang, Kequan Xu, Daoming Liang   +11 more
wiley   +1 more source

Mechanically Active Adhesive and NIR‐II‐Activated Zwitterionic Hydrogel for Infected Maxillofacial Wound Repair and Abscess Elimination

Aggregate, Volume 7, Issue 3, March 2026.
This study developed a novel zwitterionic hydrogel by incorporating cationic polymer nanoparticles (PNPs) and type III collagen (COL) into a hydrogel matrix. The material exhibits robust mechanical strength and injectability, enabling seamless adaptation to irregular wound contours.
Xiaolong Zhu, Jianxiang Ma, Duo Zhang, Zhurun Fang, Jiarong Zhang, Mingqian Wang, Ming Zhang, Ben Zhong Tang, Yuanyuan Li   +8 more
wiley   +1 more source