Results 91 to 100 of about 643,233 (285)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Creative industries international

, 2018
The integration of cultural and creative industries and international cultural policy can renew current internationalisation processes: It can serve as a source of inspiration and a driving force. It can be incorporated into foreign communication and the work of intermediary organisations, and it can also be integrated into the promotion of foreign ...
openaire   +2 more sources

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Understanding how education reform influences pre-service teachers’ teacher self-efficacy

International Journal of Educational Research Open
Internationally, governments and education authorities initiate reforms to improve schooling. However, little is known about how these reforms influence pre-service teachers’ (PST) teacher self-efficacy (TSE).
Danielle Gordon, Terri Bourke, Reece Mills, Christopher N. Blundell   +3 more
doaj   +1 more source

The economic impact of COVID-19 on the creative industries: a sub-regional input-output approach. [PDF]

Lett Spat Resour Sci, 2023
Lyons MS.
europepmc   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

The development of global creative centers from a regional perspective: A case study of Milan's creative industries. [PDF]

PLoS One, 2023
Shen C, Zhang X, Li X.
europepmc   +1 more source

The Importance of Creative Industry Agglomerations in Explaining the Wealth of European Regions [PDF]

This paper examines the existence of regional agglomerations of manufacturing, service and creative industries, the relationship between these industries and the wealth of regions and their industrial structure.
Blanca De Miguel Molina, José Luis Hervás Oliver, María De Miguel Molina, Rafael Boix Domenech   +3 more
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The role of public sector agencies and the effectiveness of the support they provide’: Examples of successful policies and strategies for growing the screen industries in Scandinavia [PDF]

, 2016
Response to the call for evidence from the Economy, Energy and Tourism Committee on the economic impact of the creative ...
Sorensen, Inge
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