Results 11 to 20 of about 73,335 (261)

CREB and Leukemogenesis [PDF]

open access: yesCritical Reviews™ in Oncogenesis, 2011
Acute myeloid leukemia (AML) is one of the most common leukemias with a 20% 5-year event-free survival in adults and 50% overall survival in children, despite aggressive chemotherapy treatment and bone marrow transplantation. The incidence and mortality rates for acute leukemia have only slightly decreased over the last 20 years, and therefore greater ...
Er-Chieh, Cho   +2 more
openaire   +2 more sources

A Novel Spatial Feature for the Identification of Motor Tasks Using High-Density Electromyography

open access: yesSensors, 2017
Estimation of neuromuscular intention using electromyography (EMG) and pattern recognition is still an open problem. One of the reasons is that the pattern-recognition approach is greatly influenced by temporal changes in electromyograms caused by the ...
Mislav Jordanić   +4 more
doaj   +1 more source

Acetylation of cAMP-responsive Element-binding Protein (CREB) by CREB-binding Protein Enhances CREB-dependent Transcription [PDF]

open access: yesJournal of Biological Chemistry, 2003
The coactivator function of cAMP-responsive element-binding protein (CREB)-binding protein (CBP) is partly caused by its histone acetyltransferase activity. However, it has become increasingly clear that CBP acetylates both histones and non-histone proteins, many of which are transcription factors. Here we investigate the role of CBP acetylase activity
Qing, Lu   +4 more
openaire   +2 more sources

Calcium carbonate supplementation causes memory impairment in mice

open access: yesAsian Pacific Journal of Tropical Medicine, 2018
Objective: To investigate the influence of calcium carbonate supplementation on cognitive function in mice. Methods: Mice were fed diets containing 1.0% calcium carbonate for 8 weeks, following which they were evaluated for memory function using object ...
Yasushi Hasegawa   +2 more
doaj   +1 more source

Hemisynthesis and Biological Evaluation of Cinnamylated, Benzylated, and Prenylated Dihydrochalcones from a Common Bio-Sourced Precursor

open access: yesAntibiotics, 2021
Several families of naturally occurring C-alkylated dihydrochalcones display a broad range of biological activities, including antimicrobial and cytotoxic properties, depending on their alkylation sidechain. The catalytic Friedel–Crafts alkylation of the
Anne Ardaillou   +4 more
doaj   +1 more source

Effect of crocin carotenoid on BDNF and CREB gene expression in brain ventral tegmental area of morphine treated rats

open access: yesAsian Pacific Journal of Tropical Biomedicine, 2018
Objective: To investigate the effect of crocin carotenoid on BNDF and CREB gene expression in the brain ventral tegmental area (VTA) and the serum level of BDNF in morphine-treated rats compared to control.
Marzieh Rezai   +5 more
doaj   +1 more source

Antidepressant effects of aqueous extract of saffron and its effects on CREB, P-CREB, BDNF, and VGF proteins in rat cerebellum

open access: yesJournal of Pharmacopuncture, 2018
Objective:The role of BDNF (brain-derived neurotrophic factor), CREB (cAMP response element binding) and VGF neuropeptide has been proved in antidepressant activity of long term saffron administration in the rat hippocampus.
Najmeh Asrari   +6 more
doaj   +1 more source

Selectivity of direct plasma treatment and plasma-conditioned media in bone cancer cell lines

open access: yesScientific Reports, 2021
Atmospheric pressure plasma jets have been shown to impact several cancer cell lines, both in vitro and in vivo. These effects are based on the biochemistry of the reactive oxygen and nitrogen species generated by plasmas in physiological liquids ...
Inès Hamouda   +4 more
doaj   +1 more source

Studying the Effect of Lactobacillus fermentum on Arc and CREB Genes Expression of Involved in The Memory of Alzheimer\'s Rats [PDF]

open access: yesMajallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Īlām, 2023
Introduction: Alzheimer's disease is a common progressive neurogenerative disease that leads to dementia and destruction of brain cells, especially in areas related to learning and memory such as the hippocampus.
Elnaz Mogaddam   +3 more
doaj  

Ending Restenosis: Inhibition of Vascular Smooth Muscle Cell Proliferation by cAMP

open access: yesCells, 2019
Increased vascular smooth muscle cell (VSMC) proliferation contributes towards restenosis after angioplasty, vein graft intimal thickening and atherogenesis.
Sarah A. Smith   +2 more
doaj   +1 more source

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