Results 201 to 210 of about 146,934 (341)

Effect of Ang II Receptor Inhibition on GSK-3β/CREB/BDNF Signalling in REM Sleep Deprivation-Induced Memory Impairment. [PDF]

Neurochem Res
Elma N, Sayan Özaçmak H, Turan İ.
europepmc   +1 more source

Glucocorticoid Receptor Activation Reprograms NK Cells to Drive AREG‐Mediated Immunosuppression: A Pan‐Cancer Role for AREG

Advanced Science, Volume 13, Issue 2, 9 January 2026.
Natural killer cells, central to anti‐tumor defense, undergo unexpected reprogramming within the tumor microenvironment. Instead of producing IFN‐γ and TNF‐α, they elevate amphiregulin, a tumor‐promoting factor. This shift is linked to glucocorticoid receptor activity and prostaglandin signaling.
Qin Wei, Guirong Liang, Rui zeng, Yuancheng Li, Anlan Hong, Hongsheng Wang, Suying Feng, Yan Wang, Yetao Wang   +8 more
wiley   +1 more source

Neuroprotective effects of Cratoxylum formosum (L.) leaf extract on β-amyloid-induced injury in human neuroblastoma SH-SY5Y cells. [PDF]

Sci Rep
Palachai N, Buranrat B, Pariwatthanakun C, Noisa P, Mairuae N.   +4 more
europepmc   +1 more source

3',5'-cyclic adenosine monophosphate-regulated enhancer binding (CREB) activity is required for normal growth and differentiated phenotype in the FRTL5 thyroid follicular cell line

, 1992
P. I. Woloshin
openalex   +1 more source

Targeting the Dynamics Between TAMs and CAR‐T Cells in Solid Tumor Therapies

Advanced Science, Volume 13, Issue 1, 5 January 2026.
This review highlights the critical role of tumor‐associated macrophages (TAMs) in affecting CAR‐T cell therapy effectiveness in solid tumors. TAMs contribute to immune suppression through cytokine secretion, immune checkpoint activation, and metabolic reprogramming, leading to CAR‐T cell exhaustion and reduced efficacy. The article explores strategies
Xiang Zhang, Hao Zheng, Zi‐Chang Liu, Ling‐Jie Luo, Xiao Dong, Xin‐Gang Cui, Yan‐Wei Wu, Liang Chen   +7 more
wiley   +1 more source

Cytoplasmic Translocation of the Transcription Factor pCREB and Altered Proteostasis in Human Islet Cells During Type 1 Diabetes Development. [PDF]

J Histochem Cytochem
Teitelman G.
europepmc   +1 more source

CSF proteomic profiling with amyloid and tau pathology identifies distinctive sex‐specific alteration of multiple proteins involved in Alzheimer's disease

Alzheimer's &Dementia, Volume 22, Issue 1, January 2026.
Abstract INTRODUCTION In Alzheimer's disease (AD), females have higher prevalence and faster progression, but sex‐specific molecular findings in AD are limited. METHODS We comprehensively examined 6162 proteins in cerebrospinal fluid (CSF) from 2496 participants to identify sex‐specific proteomic alteration by CSF amyloid beta (Aβ)42 and phosphorylated
Anh N. Do, Soomin Song, Muhammad Ali, Jigyasha Timsina, Lihua Wang, Daniel Western, Menghan Liu, Jessie Sanford, Matitee Rosende‐Roca, Merce Boada, Raquel Puerta, Edward N. Wilson, Agustin Ruiz, Pau Pastor, the Alzheimer's Disease Neuroimaging Initiative (ADNI), Tony Wyss‐Coray, Carlos Cruchaga, Yun Ju Sung   +17 more
wiley   +1 more source

GLP-1RA in JBMMSCs promoted osteogenic differentiation via modulating CREB and BRD4 signaling mediated proliferation and stemness. [PDF]

Sci Rep
Liu H, Tian Y, Bao X, Li Y.
europepmc   +1 more source

The Potential of Phytochemicals to Overcome Multidrug Resistance in Metastatic Melanoma

Chemistry &Biodiversity, Volume 23, Issue 1, January 2026.
ABSTRACT Metastatic melanoma is the most lethal form of skin cancer, accounting for most skin cancer‐related deaths. Immunotherapies and targeted therapies have improved overall and progression‐free survival rates in metastatic melanoma patients. The effectiveness of these therapies decreases due to multidrug resistance (MDR).
Jacqueline Maphutha, Danielle Twilley, Mona Dawood, Thomas Efferth, Namrita Lall   +4 more
wiley   +1 more source

Senescent Fibroblasts Drive Melanoma Progression Through GCP-2 Induced CREB Phosphorylation Enhancing Glycolysis. [PDF]

Aging Cell
Basu A, Farsam V, Singh K, Crisan D, Treiber N, Schneider LA, Huber M, Engelmeyer JI, Schumacher B, Maity P, Brandt D, Jastroch M, Mauch C, Geiger H, Kletsas D, Scharffetter-Kochanek K.   +15 more
europepmc   +1 more source