Results 211 to 220 of about 146,934 (341)

A Case of Intracranial Mesenchymal Tumor, FET::CREB Fusion-positive, Diagnosed by Genomic Profiling with FoundationOne CDx

open access: diamond
K. Sono   +7 more
openalex   +2 more sources

CREB Binding Protein Functions During Successive Stages of Eye Development in Drosophila [PDF]

open access: bronze, 2004
Justin P. Kumar   +4 more
openalex   +1 more source

Pitolisant Inhibits Alcohol Drinking and Improves Withdrawal Negative Affect Through Lateral Habenula Histaminergic Signaling in Mice

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 1, January 2026.
Pitolisant, an FDA‐approved H3R antagonist, counteracts the rewarding and sedative effects of ethanol, reduces alcohol intake, and alleviates the negative affect during withdrawal. This might occur via the antagonism of presynaptic autoreceptors and heteroreceptors H3Rs in the lateral habenula, thereby activating the H2R/p‐CREB/BDNF signaling and ...
Yan Zhao   +13 more
wiley   +1 more source

BETMB: A Dual‐Target Compound for Synergistic Suppression of Neuronal Hyperexcitability in Refractory Epilepsy via Concurrent Modulation of Nav Channels and GABAA Receptors

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 1, January 2026.
BETMB exerts multi‐target effects by positively modulating GABAARs and blocking NaV channels in a state‐dependent manner. This suppresses neuronal hyperexcitability, leading to seizure control and restoration of cognitive function. ABSTRACT Aims This study aims to evaluate 5‐(but‐1‐en‐1‐yl)‐1,2,3‐trimethoxybenzene (BETMB) as a novel dual‐target anti ...
Di Zhang   +7 more
wiley   +1 more source

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