Results 11 to 20 of about 29,744 (185)

Interventions to reduce the risk of surgically transmitted Creutzfeldt–Jakob disease: a cost-effective modelling review

Health Technology Assessment, 2020
Background: Creutzfeldt–Jakob disease is a fatal neurological disease caused by abnormal infectious proteins called prions. Prions that are present on surgical instruments cannot be completely deactivated; therefore, patients who are subsequently ...
Matt Stevenson, Lesley Uttley, Jeremy E Oakley, Christopher Carroll, Stephen E Chick, Ruth Wong   +5 more
doaj   +1 more source

CSF lactate dehydrogenase activity in patients with Creutzfeldt-Jakob disease exceeds that in other dementias [PDF]

, 2004
The diagnosis of Creutzfeldt- Jakob disease (CJD) is still made by exclusion of other dementias. We now evaluated lactate dehydrogenase (LDH) in the cerebrospinal fluid (CSF) as a possible additional diagnostic tool. CSF LDH levels of patients with CJD (
Cepek, L., Kretzschmar, H. A., Niedmann, P., Otto, M., Poser, S., Schmidt, H., Schroter, A.   +6 more
core   +1 more source

Interlaboratory validation of cerebrospinal fluid α‐synuclein quantification in the diagnosis of sporadic Creutzfeldt‐Jakob disease

Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, 2018
Introduction Cerebrospinal fluid α‐synuclein level is increased in sporadic Creutzfeldt‐Jakob disease cases. However, the clinical value of this biomarker remains to be established.
Niels Kruse, Amanda Heslegrave, Vandana Gupta, Martha Foiani, Anna Villar‐Piqué, Matthias Schmitz, Sylvain Lehmann, Charlotte Teunissen, Kaj Blennow, Henrik Zetterberg, Brit Mollenhauer, Inga Zerr, Franc Llorens   +12 more
doaj   +1 more source

Sporadic MM-1 Type Creutzfeldt-Jakob Disease With Hemiballic Presentation and No Cognitive Impairment Until Death: How New NCJDRSU Diagnostic Criteria May Allow Early Diagnosis

Frontiers in Neurology, 2018
Sporadic Creutzfeldt-Jakob disease is the most common human prion disorder. Although associated with heterogeneous clinical phenotypes, its distinctive feature is the presence of a rapidly progressive multidomain cognitive impairment.
Lorenzo Saraceno, Vito A. G. Ricigliano, Michele Cavalli, Alessandro Cagol, Giovanna Bosco, Fabio Moda, Paola Caroppo, Giovanni Meola, Giovanni Meola   +8 more
doaj   +1 more source

Cerebrospinal fluid biomarker supported diagnosis of Creutzfeldt-Jakob disease and rapid dementias:a longitudinal multicentre study over 10 years [PDF]

, 2012
To date, cerebrospinal fluid analysis, particularly protein 14-3-3 testing, presents an important approach in the identification of Creutzfeldt–Jakob disease cases.
Aguzzi, Adriano, Calero, Miguel, Gawinecka, Joanna, Green, Alison, Karch, Andre, Knight, Richard, Kulczycki, Jerzy, Ladogana, Anna, Laplanche, Jean-Louis, Mitrova, Eva, Peoc'h, Katell, Pocchiari, Maurizio, Saiz, Albert, Sanchez-Juan, Pascual, Sanchez-Valle, Raquel, Schelzke, Gabi, Sklaviadis, Theodor, Slivarichova, Dana, Stoeck, Katharina, van Duijn, Cornelia M., Zerr, Inga   +20 more
core   +1 more source

Related or not? Development of spontaneous Creutzfeldt–Jakob disease in a patient with chronic, well-controlled HIV: A case report and review of the literature

SAGE Open Medical Case Reports, 2016
Background: We report a novel case of a rare disease: spontaneous Creutzfeldt–Jakob disease in a patient with well-controlled HIV. We explore the relationship between spontaneous Creutzfeldt–Jakob disease and HIV. Case report: A 66-year-old man with long-
M-Alain Babi, Bryan D Kraft, Sweta Sengupta, Haley Peterson, Ryan Orgel, Zachary Wegermann, Njira L Lugogo, Matthew W Luedke   +7 more
doaj   +1 more source

Iatrogenic CJD due to pituitary-derived growth hormone with genetically determined incubation times of up to 40 years [PDF]

, 2015
Patients with iatrogenic Creutzfeldt-Jakob disease due to administration of cadaver-sourced growth hormone during childhood are still being seen in the UK 30 years after cessation of this treatment.
Adlard, P, Bjurstrom, N, Brandner, S, Caine, D, Collinge, J, Druyeh, R, Hummerich, H, Hyare, H, Jaunmuktane, Z, Lowe, J, Mead, S, Norsworthy, P, Rudge, P, Wadsworth, JD   +13 more
core   +1 more source

Cross infection control measures and the treatment of patients at risk of Creutzfeldt Jakob disease in UK general dental practice [PDF]

, 2001
AIMS: To determine the suitability of key infection control measures currently employed in UK dental practice for delivery of dental care to patients at risk of prion diseases.
A Smith, AF Hill, AF Hill, C P Sweeney, CM Van Duijn, DH Adams, DM Taylor, F Blanquet-Gossard, H Ashraf, IF Laurenson, J Bagg, K Arakawa, K M Roy, L Ingrosso, ME Bruce, R Dobson, RG Will, RG Will, RI Carp, RT Johnson, S Collins, T Sharp, Z Davanipour   +22 more
core   +1 more source

No Adaptation of the Prion Strain in a Heterozygous Case of Variant Creutzfeldt-Jakob Disease

Emerging Infectious Diseases, 2020
We investigated a clinical case of variant Creutzfeldt-Jakob Disease in a person heterozygous for methionine/valine at codon 129 of the prion protein gene and identified the same strain properties in variant Creutzfeldt-Jakob disease in methionine ...
Aileen Boyle, Chris Plinston, Fraser Laing, Graeme Mackenzie, Robert G. Will, Jean C. Manson, Abigail B. Diack   +6 more
doaj   +1 more source

Creutzfeldt-Jakob disease and homocysteine levels in plasma and cerebrospinal fluid [PDF]

, 2005
Background: There is evidence that homocysteine contributes to various neurodegenerative disorders. Objective: To assess the values of homocysteine in patients with Creutzfeldt-Jakob disease (CJD) in both cerebrospinal fluid (CSF) and plasma.
Bottiglieri T, Halliwell B, Hans A. Kretzschmar, Inga Zerr, Jens Wiltfang, Markus Otto, Otto M, Stefan Bleich, Stefan Kropp, Ubbink JB, Zerr I, Zerr I   +11 more
core   +1 more source