Results 31 to 40 of about 29,744 (185)

Public health concerns regarding sporadic Creutzfeldt–Jakob disease in China: a case series

Journal of International Medical Research, 2019
In this study, we report three cases of sporadic Creutzfeldt–Jakob disease in China, two confirmed cases and one probable case. The aim of this study was to enrich the data regarding clinical and epidemiological features of this disease and to provide ...
Ru-Yi Zhou, Yinzhu Zhou, Heng Zhang, Qingqing Hu, Jinjie Zhu, Jin Zhao, Shuilian Chen, Ruchun Liu, Weihong Hu, Xixing Zhang, Xianfa Xuan, Yuxue Liao, Tianmu Chen   +12 more
doaj   +1 more source

Tau protein, A beta 42 and S-100B protein in cerebrospinal fluid of patients with dementia with Lewy bodies [PDF]

, 2005
The intra vitam diagnosis of dementia with Lewy bodies (DLB) is still based on clinical grounds. So far no technical investigations have been available to support this diagnosis.
Arai H, Barbara Ciesielczyk, Brit Mollenhauer, Claudia Trenkwalder, Galasko D, Hans A. Kretzschmar, Hansen LA, Hulstaert F, Jens Wiltfang, Kanemaru K, Lukas Cepek, Manuela Neumann, Markus Otto, McKeith I, McKeith IG, McKhann G, Merdes AR, Mirko Bibl, Molina L, Otto M, Parnetti L, Petra Steinacker, Sigrid Poser, Tschampa HJ, Walter J. Schulz-Schaeffer, Watson GS   +25 more
core   +1 more source

Tissue classification for the epidemiological assessment of surgical transmission of sporadic Creutzfeldt-Jakob disease. A proposal on hypothetical risk levels

BMC Public Health, 2005
Background Epidemiological studies on the potential role of surgery in Creutzfeldt-Jakob Disease transmission have disclosed associations with history of specific surgical interventions or reported negative results.
Calero Miguel, Siden Åke, Mølbak Kåre, de Pedro-Cuesta Jesús, Rábano Alberto, Laursen Henning   +5 more
doaj   +1 more source

Genome-wide association study of behavioural and psychiatric features in human prion disease. [PDF]

, 2015
Prion diseases are rare neurodegenerative conditions causing highly variable clinical syndromes, which often include prominent neuropsychiatric symptoms.
Carswell, C, Collinge, J, Lowe, J, Lukic, A, MacKay, A, Mead, S, Porter, MC, Rudge, P, Thompson, AG, Uphill, J   +9 more
core   +1 more source

ENFERMEDAD DE JAKOB-CREUTZFELDT. A PROPÓSITO DE UN CASO

Revistas Argentina de Medicina, 2017
La enfermedad de Jakob-Creutzfeuldt esporádica es la más común de las patologías priónicas humanas. Se presenta el caso de una paciente de 59 años de edad internada por trastornos conductuales cognitivos, acompañados de mioclonías y mutismo acinético.
Lucía González, José Fernández, Vanesa Aguilar, Silvana Tobares, Melisa Contreras, Livio Lanciani, Jimena Boccardo, Juan Carlos Giugni   +7 more
doaj   +2 more sources

The most problematic symptoms of prion disease - an analysis of carer experiences [PDF]

, 2019
Objectives: Prion diseases are rare dementias that most commonly occur sporadically, but can be inherited or acquired, and for which there is no cure.
Collinge, John, Ford, Liz, Gorham, Michele, Mead, Simon, Robinson, Kathy, Rudge, Peter   +5 more
core   +2 more sources

Alzheimer's disease biomarker utilization at first referral enhances differential diagnostic precision with simultaneous exclusion of Creutzfeldt‐Jakob disease

Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring
Most suspected Creutzfeldt‐Jakob disease (CJD) cases are eventually diagnosed with other disorders. We assessed the utility of investigating Alzheimer's disease (AD) biomarkers and neurofilament light (NfL) in patients when CJD is suspected.
Zitianyu Wang, Victoria Lewis, Christiane Stehmann, Shiji Varghese, Matteo Senesi, Amelia McGlade, Laura J. Ellett, James D. Doecke, Dhamidhu Eratne, Dennis Velakoulis, Colin L. Masters, Steven J. Collins, Qiao‐Xin Li   +12 more
doaj   +1 more source

Updated clinical diagnostic criteria for sporadic Creutzfeldt-Jakob disease [PDF]

, 2017
Several molecular subtypes of sporadic Creutzfeldt-Jakob disease have been identified and electroencephalogram and cerebrospinal fluid biomarkers have been reported to support clinical diagnosis but with variable utility according to subtype.
Begue, C., Brandel, J. P., Breithaupt, M., Collie, D., Collins, S. J., Cras, P., Haik, S., Heinemann, U., Hewer, E., Jansen, Gerard H., Kallenberg, K., Ladogana, A., Meissner, B., Pimentel, J., Pocchiari, M., Roberts, H., Romero, C., Sanchez-Juan, P., Schuur, M., Smith, P., Stokin, G. B., Summers, D. M., Taratuto, A., van Duijn, C., Varges, D., Will, R. G., Zerr, I.   +26 more
core  

A Systematic Comparison of Alpha‐Synuclein Seed Amplification Assays for Increasing Reproducibility

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Seed amplification assays (SAAs) enable ultrasensitive detection of misfolded α‐synuclein across biofluids and tissues. Yet, heterogeneity in protocols limits cross‐study comparability and clinical translation. Here, we review α‐synuclein SAA methods and their performance across various biological matrices.
Manuela Amaral‐do‐Nascimento, Daniela F. Santos, Tuane C. R. G. Vieira, Tiago F. Outeiro   +3 more
wiley   +1 more source

Specific early electroencephalogram for the diagnosis of sporadic Creutzfeldt-Jakob disease

Prion
An early diagnosis is required for intervention in prion disease cases. To elucidate the specificity of early electroencephalography discharges in cases of sporadic Creutzfeldt-Jakob disease, we analysed epileptiform discharges through ...
Taiki Matsubayashi, Hirokazu Natsui, Katsuya Satoh, Tetsuyuki Kitamoto, Takanori Yokota, Nobuo Sanjo   +5 more
doaj   +1 more source