Results 31 to 40 of about 5,030,707 (174)

Clinical Features of Rapidly Progressive Alzheimer's Disease [PDF]

, 2010
Objective: To characterize clinical features, CSF biomarkers and genetic polymorphisms of patients suffering from a rapidly progressing subtype of Alzheimer's dementia (rpAD).
Meissner, Bettina, Bettina Meissner, Zerr, Inga, Redyk, Katharina, Christian Schmidt, Nico von Ahsen, Kretzschmar, Hans A., Lennart Krack, Schmidt, Christian, Roeber, Sigrun, von Ahsen, Nico, Katharina Redyk, Sigrun Roeber, Hans Kretzschmar, Inga Zerr, Krack, Lennart, Kretzschmar, Hans, Schmidt, Christian D., Krack, Lennart A., Ahsen, Nico von   +19 more
core   +1 more source

A Case of Sporadic Creutzfeldt-Jakob Disease Presenting as Conversion Disorder

Case Reports in Psychiatry, 2017
Background. Creutzfeldt-Jakob disease is a rare disorder of the central nervous system. Its initial diagnosis may be obscured by its variable presentation.
Nikhil Yegya-Raman, Rehan Aziz, Daniel Schneider, Anthony Tobia, Megan Leitch, Onyi Nwobi   +5 more
doaj   +1 more source

PrPCWD lymphoid cell targets in early and advanced chronic wasting disease of mule deer [PDF]

, 2002
Up to 15% of free-ranging mule deer in northeastern Colorado and southeastern Wyoming, USA, are afflicted with a prion disease, or transmissible spongiform encephalopathy (TSE), known as chronic wasting disease (CWD).
Keulen, L.J.M., van, van Keulen, L.J.M., Miller, M.W., Oesch, B., Hoover, E.A., Langeveld, J.P.M., Sigurdson, C.J., Barillas-Mury, C.   +7 more
core   +1 more source

Public health concerns regarding sporadic Creutzfeldt–Jakob disease in China: a case series

Journal of International Medical Research, 2019
In this study, we report three cases of sporadic Creutzfeldt–Jakob disease in China, two confirmed cases and one probable case. The aim of this study was to enrich the data regarding clinical and epidemiological features of this disease and to provide ...
Ru-Yi Zhou, Yinzhu Zhou, Heng Zhang, Qingqing Hu, Jinjie Zhu, Jin Zhao, Shuilian Chen, Ruchun Liu, Weihong Hu, Xixing Zhang, Xianfa Xuan, Yuxue Liao, Tianmu Chen   +12 more
doaj   +1 more source

Prion diseases are efficiently transmitted by blood transfusion in sheep [PDF]

, 2008
The emergence of variant Creutzfeld-Jakob disease, following on from the bovine spongiform encephalopathy (BSE) epidemic, led to concerns about the potential risk of iatrogenic transmission of disease by blood transfusion and the introduction of costly ...
Foster, J., Hunter, N., Goldmann, W., Chong, A., Gonzalez, L., Siso, S., Houston, F., McCutcheon, S., Jeffrey, M.   +8 more
core   +1 more source

ENFERMEDAD DE JAKOB-CREUTZFELDT. A PROPÓSITO DE UN CASO

Revistas Argentina de Medicina, 2017
La enfermedad de Jakob-Creutzfeuldt esporádica es la más común de las patologías priónicas humanas. Se presenta el caso de una paciente de 59 años de edad internada por trastornos conductuales cognitivos, acompañados de mioclonías y mutismo acinético.
Lucía González, José Fernández, Vanesa Aguilar, Silvana Tobares, Melisa Contreras, Livio Lanciani, Jimena Boccardo, Juan Carlos Giugni   +7 more
doaj   +2 more sources

Alzheimer's disease biomarker utilization at first referral enhances differential diagnostic precision with simultaneous exclusion of Creutzfeldt‐Jakob disease

Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring
Most suspected Creutzfeldt‐Jakob disease (CJD) cases are eventually diagnosed with other disorders. We assessed the utility of investigating Alzheimer's disease (AD) biomarkers and neurofilament light (NfL) in patients when CJD is suspected.
Zitianyu Wang, Victoria Lewis, Christiane Stehmann, Shiji Varghese, Matteo Senesi, Amelia McGlade, Laura J. Ellett, James D. Doecke, Dhamidhu Eratne, Dennis Velakoulis, Colin L. Masters, Steven J. Collins, Qiao‐Xin Li   +12 more
doaj   +1 more source

Tissue classification for the epidemiological assessment of surgical transmission of sporadic Creutzfeldt-Jakob disease. A proposal on hypothetical risk levels

BMC Public Health, 2005
Background Epidemiological studies on the potential role of surgery in Creutzfeldt-Jakob Disease transmission have disclosed associations with history of specific surgical interventions or reported negative results.
Calero Miguel, Siden Åke, Mølbak Kåre, de Pedro-Cuesta Jesús, Rábano Alberto, Laursen Henning   +5 more
doaj   +1 more source

Stage‐Dependent β‐Synuclein Links MRI and Cognitive Decline in Alzheimer's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Synaptic degeneration drives cognitive decline in Alzheimer's disease (AD), but synaptic biomarkers are scarce. Brain‐enriched β‐synuclein emerged as a synaptic damage marker. We investigated its diagnostic, prognostic, and structural correlates across the AD continuum.
Ulaş Ay, Merve Alaylioglu, Erdi Sahin, Sanem Sultan Yoruk Oner, Gulce Iskan, Gulce Cosku Yilmaz Cakan, Gozde Kizilates‐Evin, Emre Hari, Elif Kurt, Erdinc Dursun, Basar Bilgic, Hasmet Hanagasi, Hakan Gurvit, Tamer Demiralp, Duygu Gezen‐Ak, Bedia Samanci   +15 more
wiley   +1 more source

Specific early electroencephalogram for the diagnosis of sporadic Creutzfeldt-Jakob disease

Prion
An early diagnosis is required for intervention in prion disease cases. To elucidate the specificity of early electroencephalography discharges in cases of sporadic Creutzfeldt-Jakob disease, we analysed epileptiform discharges through ...
Taiki Matsubayashi, Hirokazu Natsui, Katsuya Satoh, Tetsuyuki Kitamoto, Takanori Yokota, Nobuo Sanjo   +5 more
doaj   +1 more source