Results 21 to 30 of about 5,030,707 (174)

Validation of the 2017 International Creutzfeldt-Jakob Disease Surveillance Network diagnostic criteria for sporadic Creutzfeldt-Jakob disease [PDF]

open access: yes, 2023
Sporadic Creutzfeldt-Jakob disease (sCJD) is the commonest human prion disease. sCJD is rapidly-progressive, universally fatal and transmissible.
Watson, Neil Robert John
core   +1 more source

Bioassay studies support the potential for iatrogenic transmission of variant Creutzfeldt Jakob Disease through dental procedures [PDF]

open access: yes, 2012
<p>Background: Evidence is required to quantify the potential risks of transmission of variant Creutzfeldt Jakob (vCJD) through dental procedures. Studies, using animal models relevant to vCJD, were performed to address two questions.
Elizabeth Kirby (115076)   +54 more
core   +1 more source

The controversial Third Reich history of Hans Creutzfeldt: was he a supporter or just another adept of the “hand washing policy”? [PDF]

open access: yesArquivos de Neuro-Psiquiatria, 2021
Creutzfeldt-Jakob disease (CJD) is a transmissible spongiform encephalopathy whose initial description is associated with two German authors, Alfons Maria Jakob and Hans Gerhard Creutzfeldt.
Paulo Eduardo Mestrinelli CARRILHO   +1 more
doaj   +2 more sources

CSF concentrations of cAMP and cGMP are lower in patients with Creutzfeldt-Jakob disease but not Parkinson's disease and amyotrophic lateral sclerosis. [PDF]

open access: yes, 2012
The cyclic nucleotides cyclic adenosine-3',5'-monophosphate (cAMP) and cyclic guanosine-3',5'-monophosphate (cGMP) are important second messengers and are potential biomarkers for Parkinson's disease (PD), amyotrophic lateral sclerosis (ALS) and ...
Oeckl, Patrick   +23 more
core   +1 more source

Evidence for a pathogenic role of different mutations at codon 188 of PRNP [PDF]

open access: yes, 2008
Clinical and pathological changes in familial Creutzfeldt-Jakob disease (CJD) cases may be similar or indistinguishable from sporadic CJD. Therefore determination of novel mutations in PRNP remains of major importance.
Eva-Maria Grasbon-Frodl   +49 more
core   +2 more sources

Diagnostic performance of CSF biomarkers in a well-characterized Australian cohort of sporadic Creutzfeldt-Jakob disease

open access: yesFrontiers in Neurology, 2023
The most frequently utilized biomarkers to support a pre-mortem clinical diagnosis of sporadic Creutzfeldt–Jakob disease (sCJD) include concentrations of the 14-3-3 and total tau (T-tau) proteins, as well as the application of protein amplification ...
Matteo Senesi   +18 more
doaj   +1 more source

Synthetic prions generated in vitro are similar to a newly identified subpopulation of PrPSc from sporadic Creutzfeldt-Jakob disease [PDF]

open access: yes, 2005
In recent studies, the amyloid form of recombinant prion protein (PrP) encompassing residues 89-230 (rPrP 89-230) produced in vitro induced transmissible prion disease in mice.
Bocharova, O V   +9 more
core   +1 more source

Creutzfeldt-Jakob disease: literature review based on three case reports

open access: yes, 2022
. Creutzfeldt-Jakob disease (CJD) is one of the transmissible spongiform encephalopathies that lead to rapidly progressive dementia. CJD has a low prevalence, and the average survival is only 1 year after the onset of symptoms.
Mateus Aragão Esmeraldo (10351394)   +3 more
core   +3 more sources

Detection of Infectivity in Blood of Persons with Variant and Sporadic Creutzfeldt-Jakob Disease

open access: yesEmerging Infectious Diseases, 2014
We report the presence of infectivity in erythrocytes, leukocytes, and plasma of 1 person with variant Creutzfeldt-Jakob disease and in the plasma of 2 in 4 persons whose tests were positive for sporadic Creutzfeldt-Jakob disease.
Jean Yves Douet   +11 more
doaj   +1 more source

Creutzfeldt-Jakob Disease Presenting as Nonconvulsive Status Epilepticus

open access: yesCase Reports in Neurological Medicine, 2018
Creutzfeldt-Jakob disease is a rare, rapidly progressive spongiform encephalopathy in humans. EEG plays an important role in diagnosing this disease. In some patients, epileptic activity and encephalopathy from various aetiologies may share morphological
Aleksei Rakitin   +5 more
doaj   +1 more source

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