Results 201 to 210 of about 83,953 (231)

Expression of CRH, CRH-related peptide and CRH receptor in the ovary and potential CRH signalling pathways

Journal of Reproductive Immunology, 2011
Capacity to cope with stress is crucial for survival and also reproduction. The stress response differs in the various parts of an organism. Central corticotropin-releasing hormone (CRH) has been identified to be the main stress regulator. In the reproductive system, stress has a deleterious effect on reproduction and CRH is associated with dysfunction
Gabriela, Wypior, Udo, Jeschke, Maciej, Kurpisz, Julia, Szekeres-Bartho   +3 more
openaire   +2 more sources

Corticotrophin-releasing hormone (CRH)-binding protein interference with CRH antibody binding: implications for direct CRH immunoassay

Journal of Endocrinology, 1995
Abstract Direct immunoassay of plasma corticotrophin-releasing hormone (CRH) is potentially subject to interference from high levels of CRH-binding protein (CRH-BP) that exist in the human circulation. In this study, we tested the effect of CRH-free, native CRH-BP (6·4 nmol/l) purified from human plasma, CRH-BP diluent alone, normal human ...
E A, Linton, A V, Perkins, P, Hagan, S, Poole, A F, Bristow, F, Tilders, R, Corder, C D, Wolfe   +7 more
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Expression Patterns of CRH, CRH Receptors, and CRH Binding Protein in Human Gestational Tissue at Term

Experimental and Clinical Endocrinology & Diabetes, 2003
Recent research suggests a significant role for placental corticotropin-releasing hormone (CRH) in controlling human parturition. This paper describes the expression of CRH, CRH receptors 1 and 2, and CRH binding protein (CRH-BP) in gestational tissue in late pregnancy.
Wetzka, Birgit, Sehringer, Bernd, Schäfer, Wolfgang, Biller, Silke, Hör, C., Benedek, Eszter, Deppert, Wolfgang R., Zahradnik, Hans Peter   +7 more
openaire   +3 more sources

Cutaneous expression of corticotropin‐releasing hormone (CRH), urocortin, and CRH receptors

The FASEB Journal, 2001
ABSTRACT Studies in mammalian skin have shown expression of the genes for corticotropin‐releasing hormone (CRH) and the related urocortin peptide, with subsequent production of the respective peptides. Recent molecular and biochemical analyses have further revealed the presence of CRH receptors (CRH‐Rs). These CRH‐
A, Slominski, J, Wortsman, A, Pisarchik, B, Zbytek, E A, Linton, J E, Mazurkiewicz, E T, Wei   +6 more
openaire   +2 more sources

Animal Models of CRH Deficiency

Frontiers in Neuroendocrinology, 1999
Corticotropin-releasing hormone (CRH), the major regulator of hypothalamic-pituitary-adrenal (HPA) axis, was first isolated due to its ability to stimulate the release of adrenocorticotropic hormone from the anterior pituitary. Later, it was also found to have also a wide spectrum of actions within the central nervous system and the periphery.
M, Venihaki, J A, Majzoub
openaire   +2 more sources

CRH-R1 and CRH-R2 differentially modulate dendritic outgrowth of hippocampal neurons

Endocrine, 2012
Corticotropin-releasing hormone (CRH) has been implicated to be involved in the development of dendrites in brain. In the present study, we examined the effect of CRH on dendrite outgrowth in primary cultured hippocampal neurons and defined the specific CRH receptor subtype involved. Treatment of neurons with increasing concentration of CRH resulted in
Hui, Sheng, Yongjun, Xu, Yanming, Chen, Yanmin, Zhang, Xiaohui, Xu, Cheng, He, Xin, Ni   +6 more
openaire   +2 more sources

CRH and α-helical-CRH modulate behavioral measures of arousal in monkeys

Pharmacology Biochemistry and Behavior, 1989
Several neuropeptides involved in the control of pituitary-adrenal activation have also been shown to have behavioral effects which may be mediated by actions on brain mechanisms independent of pituitary release. The behavioral effects of intraventricular administration of CRH and the synthetic peptide antagonist alpha-helical-CRH were assessed in ...
J T, Winslow, J D, Newman, T R, Insel
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Lessons from CRH knockout mice

Neuropeptides, 2002
Corticotropin-releasing hormone (CRH), the major regulator of hypothalamic-pituitary-adrenal (HPA) axis, has a wide spectrum of actions within the central nervous system and the periphery. The development and use of Crh knockout mice (Crh-/-) has been an important tool for addressing the physiologic and pathologic roles of CRH.
M, Venihaki, J, Majzoub
openaire   +2 more sources

Corticotropin-releasing hormone (CRH) and CRH receptor 1 gene expression in vitiligo

Clinical and Experimental Dermatology, 2016
Vitiligo is a disorder characterized by depigmented patches in the skin. Psychological stress can activate the hypothalamic-pituitary-adrenal axis in the brain as well as on the peripheral level and aggravate autoimmune skin diseases. Skin appendages have dual functions dually as prominent targets and sources of the peripheral corticotropin-releasing ...
O G, Shaker, S M R, Eltahlawi, S O, Tawfic, A M, Eltawdy, N I E, Bedair   +4 more
openaire   +2 more sources

Brake Distance Calculation of CRH

Applied Mechanics and Materials, 2012
With the development of high-speed railway in China, CRH is widely used in railway transportation. Traditional method of braking distance calculation is not suitable for CRH. In this paper, a more accurate brake distance of CRH locomotive has been calculated by using the calculus form of the kinematics formulas and verified by real data.
null Xu Peng, null Yingying Zhou, null Qianyong Li, null Xiaoqiong He   +3 more
openaire   +1 more source