Results 211 to 220 of about 83,953 (231)
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The Peripheral CRH/Urocortin System
Annals of the New York Academy of Sciences, 2000Abstract:The hypothalmus‐pituitary‐adrenal (HPA) axis and the immune system communicate at multiple levels: On the one hand, immune system‐derived substances, such as interleukin‐1, interleukin‐6, tumor necrosis factor alpha, and leukemia inhibitory factor can stimulate the HPA axis.
C M, Bamberger, A M, Bamberger
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Endocrine, 2005
Corticotropin-releasing hormone (CRH) is one of the major proteins responsible for brain stress regulation. Two well-known receptors have been described: type 1 and type 2alpha, both members of the receptor superfamily of G protein-coupled receptors (GPCR).
G, Maya-Núñez +2 more
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Corticotropin-releasing hormone (CRH) is one of the major proteins responsible for brain stress regulation. Two well-known receptors have been described: type 1 and type 2alpha, both members of the receptor superfamily of G protein-coupled receptors (GPCR).
G, Maya-Núñez +2 more
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CRH in chronic inflammatory stress
Peptides, 2001Corticotropin-releasing hormone (CRH) is an important regulator of inflammation at the central level through hypothalamo-pituitary-adrenal (HPA) axis control of glucocorticoid secretion. Integrity of the HPA axis during autoimmune disease is critical in controlling the severity of inflammation, but the evidence for an HPA axis defect in the etiology of
Jessop, DS, Harbuz, MS, Lightman, SL
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Journal of Neuroimmunology, 1997
Inflammatory cytokines released during immune system activation can stimulate the hypothalamic-pituitary-adrenal axis and cause increased secretion of corticotropin-releasing hormone (CRH), adrenocorticotropin and glucocorticoids. Identification of CRH peptide and mRNA, as well as its receptors in immune tissues, suggested a role for this peptide as a ...
K, Karalis +4 more
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Inflammatory cytokines released during immune system activation can stimulate the hypothalamic-pituitary-adrenal axis and cause increased secretion of corticotropin-releasing hormone (CRH), adrenocorticotropin and glucocorticoids. Identification of CRH peptide and mRNA, as well as its receptors in immune tissues, suggested a role for this peptide as a ...
K, Karalis +4 more
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Alpha-Helical CRH Exerts CRH Agonistic Effects on Sleep-Endocrine Activity in Humans
Neuropsychobiology, 2005CRH is known to enhance wakefulness and to reduce SWS. In addition, some but not all, studies suggest that CRH promotes REM sleep. Alpha-helical CRH exerts CRH-antagonistic effects in various studies. We studied its effect on sleep EEG and nocturnal secretion of ACTH, cortisol, GH (n = 7) in young normal male subjects. After administering the substance
Katja, Held +4 more
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Does the CRH Binding Protein Shield the Anterior Pituitary from Placental CRH?
Endocrine, 1998Corticotropin releasing factor (CRH) is released from the hypothalamus and travels to the anterior pituitary where it stimulates the release of adrenocorticotropin (ACTH). In turn, ACTH travels through the blood and stimulates the release of cortisol from the adrenal. The placenta is also a source of CRH and is responsible for the dramatic rises in CRH
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