Results 211 to 220 of about 50,942 (257)
Nanocarrier-mediated CRISPR-Cas delivery: a novel approach against antibiotic-resistant superbugs. [PDF]
Saudi Pharm JAlmufarriji FM.
europepmc +1 more source
CRISPR-Cas based plasmid design for multidrug-resistant Klebsiella pneumoniae isolates. [PDF]
FEMS Microbiol LettBaba S, Oncul O, Aktas Z.
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Chronic In Vivo CRISPR-Cas Genome Editing: Challenges, Long-Term Safety, and Outlook. [PDF]
CellsBao C +6 more
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Unlocking genome engineering in <i>Alcaligenes faecalis</i> by exploiting its native type I-F CRISPR-Cas. [PDF]
Microbiol SpectrCheng W +9 more
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Methods, 2020
Clustered regularly interspaced short palindromic repeats (CRISPR) and their associated proteins (Cas) are essential genetic elements in many archaeal and bacterial genomes, playing a key role in a prokaryote adaptive immune system against invasive foreign elements.
Alkhnbashi, Omer S. +4 more
openaire +3 more sources
Clustered regularly interspaced short palindromic repeats (CRISPR) and their associated proteins (Cas) are essential genetic elements in many archaeal and bacterial genomes, playing a key role in a prokaryote adaptive immune system against invasive foreign elements.
Alkhnbashi, Omer S. +4 more
openaire +3 more sources
CRISPR-Cas-mediated diagnostics
Trends in Biotechnology, 2022An ideal molecular diagnostic method should be sensitive, specific, low cost, rapid, portable, and easy to operate. Traditional nucleic acid detection methods based mainly on PCR technology have not only high sensitivity and specificity, but also some limitations, such as the need for expensive equipment and skilled technicians, being both time and ...
Luoxi, Li +5 more
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Chemie in unserer Zeit, 2017
ZusammenfassungCRISPR‐Cas ist ein adaptives und vererbbares Immunsystem, mit dem sich Prokaryoten gegen invasive genetische Elemente wie Viren wehren. Es eignet sich aber auch hervorragend zur Manipulation von Genomen. Die Nuklease Cas9 wird durch eine Leit‐RNA zu einem bestimmten DNA‐Abschnitt geführt und fügt dort einen Doppelstrangbruch ein.
Larissa Tetsch +2 more
openaire +2 more sources
ZusammenfassungCRISPR‐Cas ist ein adaptives und vererbbares Immunsystem, mit dem sich Prokaryoten gegen invasive genetische Elemente wie Viren wehren. Es eignet sich aber auch hervorragend zur Manipulation von Genomen. Die Nuklease Cas9 wird durch eine Leit‐RNA zu einem bestimmten DNA‐Abschnitt geführt und fügt dort einen Doppelstrangbruch ein.
Larissa Tetsch +2 more
openaire +2 more sources