Results 241 to 250 of about 1,254,871 (374)

Expanding the CRISPR/Cas toolkit: applications in proteomics and theranostics. [PDF]

Front Bioeng Biotechnol
Punde A, Dey S, Pandire R, Bhattacharjee A, Patra C.   +4 more
europepmc   +1 more source

Application and Prospective of CRISPR-Cas in Cancer Diagnosis and Therapy

Xiaoshu Li
openalex   +2 more sources

Additional file 3 of Exploring the success of Brazilian endemic clone Pseudomonas aeruginosa ST277 and its association with the CRISPR-Cas system type I-C

, 2020
Melise Chaves Silveira, Cláudio Marcos Rocha-de-Souza, Rodolpho Mattos Albano, Ivson Cassiano de Oliveira Santos, Ana Paula D’Alincourt Carvalho-Assef   +4 more
openalex   +1 more source

Endocytic Control of Cell‐Autonomous and Non‐Cell‐Autonomous Functions of p53

Advanced Science, EarlyView.
NUMB Ex3‐containing isoforms localize to the plasma membrane, where they recruit p53 through SNX9 and direct it to multivesicular bodies and exosomes. Exported p53 is taken up by neighboring cells and activates nuclear programs, revealing an intercellular, exosome‐based pathway that might help establish a tumor‐suppressive microenvironment.
Roberta Cacciatore, Andrea Basile, Stefano Freddi, Irene Schiano Lomoriello, Carlo Ribelle Zucca, Giuseppe Ciossani, Luigi Scietti, Alessandro Cuomo, Simona Ronzoni, Simone Pelicci, Mario Faretta, Elena Zaccheroni, Giuliana Pelicci, Vittoria Matafora, Angela Bachi, Rosalind Helen Gunby, Salvatore Pece, Sara Sigismund, Letizia Lanzetti, Ivan Nicola Colaluca, Pier Paolo Di Fiore   +20 more
wiley   +1 more source

Efficient CRISPR-Cas genome editing in brown algae. [PDF]

Cell Rep Methods
Martinho C, Hoshino M, Raphalen M, Bukhanets V, Kerur A, Bogaert KA, Luthringer R, Coelho SM.   +7 more
europepmc   +1 more source

PolydopaminePowered Droplet Electricity Generatorfor Protein Assay with CRISPR/Cas Enabled Amplification

Xiaolin Qu (10145987), Yuyan Yue (21009143), Yuguo Tang (1630528), Jin Jiao (9333607), Peng Miao (462722)   +4 more
openalex   +1 more source

Palmitoylation‐Mediated Ubiquitination of SRPK1 Regulates Ferroptosis in High‐Fat‐Induced Erectile Dysfunction

Advanced Science, EarlyView.
Elevated exogenous palmitic acid promotes the S‐palmitoylation of SRPK1 in endothelial cells, a dynamic process governed by ZDHHC24 and APT1. This post‐translational modification strengthens the interaction between SRPK1 and the E3 ubiquitin ligase MIB1, thereby facilitating the proteasomal degradation of SRPK1.
Xiao‐Hui Tan, Ke‐Fan Li, Yi‐Ming Yuan, Man‐Cheng Xia, Fang‐Zhou Zhao, Hong‐Gang Ying, Zhuo Zhou, Peng‐Chao Gao, Guo‐Qing Xie, Xue‐Song Li, Hui Jiang, Rui‐Li Guan   +11 more
wiley   +1 more source

CRISPR-Cas Technology Turns Chlamydomonas reinhardtii into a Flagship for Algal Biotechnology. [PDF]

Mar Drugs
Antonacci A, Masi A, Vedi V, Colella S, Musella F, Fiorentino G, Scognamiglio V.   +6 more
europepmc   +1 more source

Biosensing platforms for DNA diagnostics based on CRISPR/Cas nucleases: towards the detection of nucleic acids at the level of single molecules in non-laboratory settings [PDF]

Svetlana A. Khmeleva, K. G. Ptitsyn, Leonid K. Kurbatov, О.С. Тимошенко, Elena V. Suprun, Sergey P. Radko, А.В. Лисица   +6 more
openalex   +1 more source

Quantitative Proteomics and CRISPR/Cas9 Editing Reveal UPR‐Mediated Control of Immunoglobulin Homeostasis in Hybridomas

Advanced Science, EarlyView.
BCR sequencing and subclone analysis correlated immunoglobulin (Ig) chain loss in dysfunctional hybridomas with disrupted monoclonal antibody homeostasis. Proteomics‐guided CRISPR/Cas9 editing revealed that the unfolded protein response (UPR) regulates aberrant Ig synthesis.
Rubing Zou, Xinying Lu, Ying Liu, Peiyu Yang, Shuo Sun, Yihua Liu, Yinyuan Mo, Guonian Zhu, Jae Seong Lee, Yirong Guo   +9 more
wiley   +1 more source